Tethering RITS to a nascent transcript initiates RNAi-and heterochromatin-dependent gene silencing M Bühler, A Verdel, D Moazed Cell 125 (5), 873-886, 2006 | 428 | 2006 |
Single cell RNA-sequencing of pluripotent states unlocks modular transcriptional variation AA Kolodziejczyk, JK Kim, JCH Tsang, T Ilicic, J Henriksson, ... Cell stem cell 17 (4), 471-485, 2015 | 347 | 2015 |
Transcription and RNAi in heterochromatic gene silencing M Bühler, D Moazed Nature structural & molecular biology 14 (11), 1041-1048, 2007 | 267 | 2007 |
RNAi-dependent and-independent RNA turnover mechanisms contribute to heterochromatic gene silencing M Bühler, W Haas, SP Gygi, D Moazed Cell 129 (4), 707-721, 2007 | 260 | 2007 |
EJC-independent degradation of nonsense immunoglobulin-μ mRNA depends on 3′ UTR length M Bühler, S Steiner, F Mohn, A Paillusson, O Mühlemann Nature structural & molecular biology 13 (5), 462-464, 2006 | 249 | 2006 |
Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer P Tropberger, S Pott, C Keller, K Kamieniarz-Gdula, M Caron, F Richter, ... Cell 152 (4), 859-872, 2013 | 192 | 2013 |
TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway M Bühler, N Spies, DP Bartel, D Moazed Nature structural & molecular biology 15 (10), 1015, 2008 | 190 | 2008 |
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl (2) d P Knuckles, T Lence, IU Haussmann, D Jacob, N Kreim, SH Carl, ... Genes & development 32 (5-6), 415-429, 2018 | 157 | 2018 |
Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast SM Buker, T Iida, M Bühler, J Villén, SP Gygi, JI Nakayama, D Moazed Nature structural & molecular biology 14 (3), 200-207, 2007 | 140 | 2007 |
HP1Swi6 mediates the recognition and destruction of heterochromatic RNA transcripts C Keller, R Adaixo, R Stunnenberg, KJ Woolcock, S Hiller, M Bühler Molecular cell 47 (2), 215-227, 2012 | 126 | 2012 |
Long intronic GAA repeats causing Friedreich ataxia impede transcription elongation T Punga, M Bühler EMBO molecular medicine 2 (4), 120-129, 2010 | 102 | 2010 |
Nuclear retention of fission yeast dicer is a prerequisite for RNAi-mediated heterochromatin assembly S Emmerth, H Schober, D Gaidatzis, T Roloff, K Jacobeit, M Bühler Developmental cell 18 (1), 102-113, 2010 | 88 | 2010 |
Noncoding RNAs prevent spreading of a repressive histone mark C Keller, R Kulasegaran-Shylini, Y Shimada, HR Hotz, M Bühler Nature structural & molecular biology 20 (8), 994, 2013 | 87 | 2013 |
Silent chromatin at the middle and ends: lessons from yeasts M Bühler, SM Gasser The EMBO journal 28 (15), 2149-2161, 2009 | 87 | 2009 |
Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombe KJ Woolcock, D Gaidatzis, T Punga, M Bühler Nature structural & molecular biology 18 (1), 94, 2011 | 86 | 2011 |
The Paf1 complex represses small-RNA-mediated epigenetic gene silencing KM Kowalik, Y Shimada, V Flury, MB Stadler, J Batki, M Bühler Nature 520 (7546), 248-252, 2015 | 74 | 2015 |
Transcriptional silencing of nonsense codon-containing immunoglobulin minigenes M Bühler, F Mohn, L Stalder, O Mühlemann Molecular cell 18 (3), 307-317, 2005 | 73 | 2005 |
Efficient downregulation of immunoglobulin μ mRNA with premature translation-termination codons requires the 5′-half of the VDJ exon M Bühler, A Paillusson, O Mühlemann Nucleic acids research 32 (11), 3304-3315, 2004 | 73 | 2004 |
RNA fate determination through cotranscriptional adenosine methylation and microprocessor binding P Knuckles, SH Carl, M Musheev, C Niehrs, A Wenger, M Bühler Nature structural & molecular biology 24 (7), 561, 2017 | 70 | 2017 |
Intranuclear degradation of nonsense codon‐containing mRNA M Bühler, MF Wilkinson, O Mühlemann EMBO reports 3 (7), 646-651, 2002 | 67 | 2002 |