Reverse engineering of regulatory networks in human B cells K Basso, AA Margolin, G Stolovitzky, U Klein, R Dalla-Favera, A Califano Nature genetics 37 (4), 382-390, 2005 | 1451 | 2005 |
Human Immunoglobulin (Ig)M+IgD+ Peripheral Blood B Cells Expressing the CD27 Cell Surface Antigen Carry Somatically Mutated Variable Region Genes … U Klein, K Rajewsky, R Küppers The Journal of experimental medicine 188 (9), 1679-1689, 1998 | 1248 | 1998 |
Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells U Klein, Y Tu, GA Stolovitzky, M Mattioli, G Cattoretti, H Husson, ... The Journal of experimental medicine 194 (11), 1625-1638, 2001 | 1093 | 2001 |
Germinal centres: role in B-cell physiology and malignancy U Klein, R Dalla-Favera Nature Reviews Immunology 8 (1), 22-33, 2008 | 958 | 2008 |
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH 2 responses Y Zheng, A Chaudhry, A Kas, P Deroos, JM Kim, TT Chu, L Corcoran, ... Nature 458 (7236), 351-356, 2009 | 894 | 2009 |
Cellular origin of human B-cell lymphomas R Küppers, ULF Klein, ML Hansmann, K Rajewsky New England Journal of Medicine 341 (20), 1520-1529, 1999 | 837 | 1999 |
The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia U Klein, M Lia, M Crespo, R Siegel, Q Shen, T Mo, A Ambesi-Impiombato, ... Cancer cell 17 (1), 28-40, 2010 | 827 | 2010 |
Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination U Klein, S Casola, G Cattoretti, Q Shen, M Lia, T Mo, T Ludwig, ... Nature immunology 7 (7), 773-782, 2006 | 706 | 2006 |
Dynamics of B cells in germinal centres NS De Silva, U Klein Nature reviews immunology 15 (3), 137-148, 2015 | 682 | 2015 |
BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci L Pasqualucci, A Migliazza, N Fracchiolla, C William, A Neri, L Baldini, ... Proceedings of the National Academy of Sciences 95 (20), 11816-11821, 1998 | 551 | 1998 |
Transcriptional analysis of the B cell germinal center reaction U Klein, Y Tu, GA Stolovitzky, JL Keller, J Haddad, V Miljkovic, G Cattoretti, ... Proceedings of the National Academy of Sciences 100 (5), 2639-2644, 2003 | 467 | 2003 |
Loss of the B-lineage–specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma I Schwering, A Bräuninger, U Klein, B Jungnickel, M Tinguely, V Diehl, ... Blood, The Journal of the American Society of Hematology 101 (4), 1505-1512, 2003 | 444 | 2003 |
Transcriptional control of adipose lipid handling by IRF4 J Eguchi, X Wang, S Yu, EE Kershaw, PC Chiu, J Dushay, JL Estall, ... Cell metabolism 13 (3), 249-259, 2011 | 414 | 2011 |
Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease T Goossens, U Klein, R Küppers Proceedings of the National Academy of Sciences 95 (5), 2463-2468, 1998 | 402 | 1998 |
Somatic hypermutation in normal and transformed human B cells U Klien, T Goasens, M Fischer, H Kanzler, A Braeuninger, K Rajewsky, ... Immunological reviews 162 (1), 261-280, 1998 | 398 | 1998 |
An essential role for the IL-2 receptor in T reg cell function T Chinen, AK Kannan, AG Levine, X Fan, U Klein, Y Zheng, G Gasteiger, ... Nature immunology 17 (11), 1322-1333, 2016 | 350 | 2016 |
Evidence for a large compartment of IgM-expressing memory B cells in humans U Klein, R Küppers, K Rajewsky Blood, The Journal of the American Society of Hematology 89 (4), 1288-1298, 1997 | 337 | 1997 |
Quantitative noise analysis for gene expression microarray experiments Y Tu, G Stolovitzky, U Klein Proceedings of the National Academy of Sciences 99 (22), 14031-14036, 2002 | 328 | 2002 |
Gene expression in Wilms’ tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition CM Li, M Guo, A Borczuk, CA Powell, M Wei, HM Thaker, R Friedman, ... The American journal of pathology 160 (6), 2181-2190, 2002 | 289 | 2002 |
Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets PP Piccaluga, C Agostinelli, A Califano, M Rossi, K Basso, S Zupo, ... The Journal of clinical investigation 117 (3), 823-834, 2007 | 287 | 2007 |