Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design J Koehbach, M O’Brien, M Muttenthaler, M Miazzo, M Akcan, AG Elliott, ... Proceedings of the National Academy of Sciences 110 (52), 21183-21188, 2013 | 158 | 2013 |
Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy M Akcan, MR Stroud, SJ Hansen, RJ Clark, NL Daly, DJ Craik, JM Olson Journal of Medicinal chemistry 54 (3), 782-787, 2011 | 119 | 2011 |
Cyclization of conotoxins to improve their biopharmaceutical properties RJ Clark, M Akcan, Q Kaas, NL Daly, DJ Craik Toxicon 59 (4), 446-455, 2012 | 95 | 2012 |
Characterization of a Novel Alpha-Conotoxin TxID from Conus textile that Potently Blocks rat Alpha3beta4 Nicotinic Acetylcholine Receptors S Luo, D Zhangsun, X Zhu, Y Wu, Y Hu, S Christensen, PJ Harvey, ... Journal of Medicinal Chemistry, 2013 | 81 | 2013 |
Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro CI Schroeder, JE Swedberg, JM Withka, KJ Rosengren, M Akcan, ... Chemistry & biology 21 (2), 284-294, 2014 | 80 | 2014 |
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition SJ de Veer, JE Swedberg, M Akcan, KJ Rosengren, M Brattsand, DJ Craik, ... Biochemical Journal 469 (2), 243-253, 2015 | 68 | 2015 |
Characterization of a novel α-conotoxin from conus textile that selectively targets α6/α3β2β3 nicotinic acetylcholine receptors S Luo, D Zhangsun, Y Wu, X Zhu, Y Hu, M McIntyre, S Christensen, ... Journal of Biological Chemistry 288 (2), 894-902, 2013 | 62 | 2013 |
Less is more: design of a highly stable disulfide-deleted mutant of analgesic cyclic α-conotoxin Vc1. 1 R Yu, VAL Seymour, G Berecki, X Jia, M Akcan, DJ Adams, Q Kaas, ... Scientific reports 5 (13264), 2015 | 55 | 2015 |
Synthesis of new thiophene, furan and pyridine substituted 1, 2, 4, 5-oxadiazaboroles Y Dürüst, M Akcan, O Martiskainen, E Siirola, K Pihlaja Polyhedron 27 (3), 999-1007, 2008 | 23 | 2008 |
Transforming conotoxins into cyclotides: backbone cyclization of P‐superfamily conotoxins M Akcan, RJ Clark, NL Daly, AC Conibear, A de Faoite, MD Heghinian, ... Peptide Science 104 (6), 682-692, 2015 | 17 | 2015 |
Synthesis of cyclic disulfide-rich peptides M Akcan, DJ Craik Peptide Synthesis and Applications, 89-101, 2013 | 14 | 2013 |
Potentiometric Study of Acid− Base Equilibria of 3, 5-Disubstituted 1, 2, 4, 5-Oxadiazaboroles in Nonaqueous Media Y Dürüst, N Dürüst, M Akcan Journal of Chemical & Engineering Data 52 (3), 718-720, 2007 | 13 | 2007 |
Characterization of a novel a-conotoxin from conus textile that selectively targets a6/a3b2b3 nicotinic acetylcholine receptors S Luo, D Zhangsun, Y Wu, X Zhu, Y Hu, M McIntyre, S Christensen, ... J. Biol. Chem 288, 894-902, 2013 | 11 | 2013 |
The three-dimensional solution structure of mini-M conotoxin BtIIIA reveals a disconnection between disulfide connectivity and peptide fold M Akcan, Y Cao, F Chongxu, DJ Craik Bioorganic & Medicinal Chemistry, 2013 | 8 | 2013 |
Preparation, Characterization and Antibacterial Activity of Malva Sylvestris L. Seed Extract Containing Novel Electrospun PVA Nanofibers K Turan, M Akcan, OM Kalfa Gazi University Journal of Science 34 (4), 987-998, 2021 | 5 | 2021 |
Engineering venom peptides to improve their stability and bioavailability M Akcan, DJ Craik Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics …, 2015 | 5 | 2015 |
Cyclotide-rich fractions containing nanofibers by electrospinning: preparation, characterization and examination of antimicrobial activity EB BAŞ, C KÜREKCİ, OM Kalfa, M Akcan Turkish Journal of Chemistry 46 (5), 1651-1660, 2022 | 3 | 2022 |
Discovery and applications of naturally occurring cyclic peptides D Craik, A Poth, M Colgrave, M Akcan, B Oku, A Chan, N Daly Planta Medica 77 (12), L8, 2011 | 3 | 2011 |
The ring closure reactions of amidoximes with phenylboronic acid M Akcan Fen Bilimleri Enstitüsü, 2007 | 3 | 2007 |
Enhancing the Stability of Tumor Homing LyP-1 Peptide Using Cyclization and Retro Grafting Strategies Ş Kara, E Ayazoglu Demir, S Celik Uzuner, M Akcan International Journal of Peptide Research and Therapeutics 29 (2), 30, 2023 | 1 | 2023 |