David Brocks
David Brocks
Postdoctoral researcher, Weizmann Institute of Science
Verified email at
Cited by
Cited by
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells
D Walter, A Lier, A Geiselhart, FB Thalheimer, S Huntscha, MC Sobotta, ...
Nature 520 (7548), 549-552, 2015
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis
N Cabezas-Wallscheid, D Klimmeck, J Hansson, DB Lipka, A Reyes, ...
Cell stem cell 15 (4), 507-522, 2014
DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
CC Oakes, M Seifert, Y Assenov, L Gu, M Przekopowitz, AS Ruppert, ...
Nature genetics 48 (3), 253-264, 2016
Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer
D Brocks, Y Assenov, S Minner, O Bogatyrova, R Simon, C Koop, ...
Cell reports 8 (3), 798-806, 2014
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ...
Nature genetics 49 (7), 1052-1060, 2017
Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia
CC Oakes, R Claus, L Gu, Y Assenov, J Hüllein, M Zucknick, M Bieg, ...
Cancer discovery 4 (3), 348-361, 2014
Quiescence-induced LncRNAs trigger H4K20 trimethylation and transcriptional silencing
H Bierhoff, MA Dammert, D Brocks, S Dambacher, G Schotta, I Grummt
Molecular cell 54 (4), 675-682, 2014
RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia
DB Lipka, T Witte, R Toth, J Yang, M Wiesenfarth, P Nöllke, A Fischer, ...
Nature communications 8 (1), 2126, 2017
Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation
N Blagitko-Dorfs, P Schlosser, G Greve, D Pfeifer, R Meier, A Baude, ...
Leukemia 33 (4), 945-956, 2019
Integrative analysis defines distinct prognostic subgroups of intrahepatic cholangiocarcinoma
B Goeppert, R Toth, S Singer, T Albrecht, DB Lipka, P Lutsik, D Brocks, ...
Hepatology 69 (5), 2091-2106, 2019
Intratumor heterogeneity in epigenetic patterns
Y Assenov, D Brocks, C Gerhäuser
Seminars in cancer biology 51, 12-21, 2018
Reactivation of endogenous retroviral elements via treatment with DNMT-and HDAC-inhibitors
M Daskalakis, D Brocks, YH Sheng, MS Islam, A Ressnerova, Y Assenov, ...
Cell Cycle 17 (7), 811-822, 2018
Mobile genomics: tools and techniques for tackling transposons
K O'Neill, D Brocks, MG Hammell
Philosophical Transactions of the Royal Society B 375 (1795), 20190345, 2020
Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite …
DB Lipka, Q Wang, N Cabezas-Wallscheid, D Klimmeck, D Weichenhan, ...
Cell Cycle 13 (22), 3476-3487, 2014
ICGC Early Onset Prostate Cancer Project: Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer
D Brocks, Y Assenov, S Minner, O Bogatyrova, R Simon, C Koop, ...
Cell Rep 8 (3), 798-806, 2014
Musical patterns for comparative epigenomics
D Brocks
Clinical Epigenetics 7, 1-5, 2015
Single cell analysis reveals dynamics of transposable element transcription following epigenetic de-repression
D Brocks, E Chomsky, Z Mukamel, A Lifshitz, A Tanay
BioRxiv, 462853, 2018
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