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Amit Deshmukh
Amit Deshmukh
Hospital for Sick Children
Verified email at sickkids.ca
Title
Cited by
Cited by
Year
Human DNA ligases: a comprehensive new look for cancer therapy
DK Singh, S Krishna, S Chandra, M Shameem, AL Deshmukh, ...
Medicinal Research Reviews 34 (3), 567-595, 2014
372014
FAN1, a DNA repair nuclease, as a modifier of repeat expansion disorders
AL Deshmukh, A Porro, M Mohiuddin, S Lanni, GB Panigrahi, MC Caron, ...
Journal of Huntington's disease 10 (1), 95-122, 2021
362021
Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening
AL Deshmukh, S Chandra, DK Singh, MI Siddiqi, D Banerjee
Molecular BioSystems 13 (8), 1630-1639, 2017
352017
A Novel Benzocoumarin-Stilbene Hybrid as a DNA ligase I inhibitor with in vitro and in vivo anti-tumor activity in breast cancer models
MK Hussain, DK Singh, A Singh, M Asad, MI Ansari, M Shameem, ...
Scientific reports 7 (1), 10715, 2017
182017
siRNA delivery using a cationic-lipid-based highly selective human DNA Ligase I inhibitor
SR Bathula, K Sharma, DK Singh, MP Reddy, PR Sajja, AL Deshmukh, ...
ACS applied materials & interfaces 10 (2), 1616-1622, 2018
162018
FAN1 exo-not endo-nuclease pausing on disease-associated slipped-DNA repeats: A mechanism of repeat instability
AL Deshmukh, MC Caron, M Mohiuddin, S Lanni, GB Panigrahi, M Khan, ...
Cell Reports 37 (10), 2021
152021
Dynamics of replication proteins during lagging strand synthesis: A crossroads for genomic instability and cancer
AL Deshmukh, C Kumar, DK Singh, P Maurya, D Banerjee
DNA repair 42, 72-81, 2016
112016
Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum
K Mätlik, M Baffuto, L Kus, AL Deshmukh, DA Davis, MR Paul, TS Carroll, ...
Nature Genetics, 1-12, 2024
102024
Identification of a novel human DNA ligase I inhibitor that promotes cellular apoptosis in DLD-1 cells: an in silico and in vitro mechanistic study
DK Singh, MK Hussain, S Krishna, AL Deshmukh, M Shameem, P Maurya, ...
RSC advances 6 (97), 94574-94587, 2016
62016
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability
T Gall-Duncan, J Luo, CM Jurkovic, LA Fischer, K Fujita, AL Deshmukh, ...
Cell 186 (22), 4898-4919. e25, 2023
42023
Mechanisms of somatic CAG-repeat expansions in Huntington's disease
AL Deshmukh, T Gall-Duncan, CE Pearson
Huntington's Disease, 117-133, 2024
2024
Assays and protocols for the detection of cancer metastasis
AL Deshmukh, DK Singh
Protocol Handbook for Cancer Biology, 69-86, 2021
2021
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