| Activated protein C variants with normal cytoprotective but reduced anticoagulant activity LO Mosnier, AJ Gale, S Yegneswaran, JH Griffin Blood 104 (6), 1740-1744, 2004 | 207 | 2004 |
| Endothelial protein C receptor CT Esmon, J Xu, J Gu, D Qu, Z Laszik, G Ferrell, DJ Stearns-Kurosawa, ... Thrombosis and haemostasis 82 (08), 251-258, 1999 | 183 | 1999 |
| Bisarylhydrazones as Exchangeable Biocompatible Linkers A Dirksen, S Yegneswaran, PE Dawson Angewandte Chemie (International ed. in English) 49 (11), 2023, 2010 | 147 | 2010 |
| Protein S alters the active site location of activated protein C above the membrane surface S Yegneswaran, GM Wood, CT Esmon, AE Johnson Journal of Biological Chemistry 272 (40), 25013-25021, 1997 | 133 | 1997 |
| Sphingolipids as bioactive regulators of thrombin generation H Deguchi, S Yegneswaran, JH Griffin Journal of Biological Chemistry 279 (13), 12036-12042, 2004 | 73 | 2004 |
| Relocating the active site of activated protein C eliminates the need for its protein S cofactor: a fluorescence resonance energy transfer study S Yegneswaran, MD Smirnov, O Safa, NL Esmon, CT Esmon, ... Journal of Biological Chemistry 274 (9), 5462-5468, 1999 | 61 | 1999 |
| Interaction of the A1 subunit of factor VIIIa and the serine protease domain of factor X identified by zero-length cross-linking KA Lapan, PJ Fay Thrombosis and haemostasis 80 (09), 418-422, 1998 | 52 | 1998 |
| Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data H Deguchi, Y Banerjee, S Trauger, G Siuzdak, E Kalisiak, JA Fernández, ... Blood, The Journal of the American Society of Hematology 126 (13), 1595-1600, 2015 | 49 | 2015 |
| Identification of distinct sequences in human blood coagulation factor Xa and prothrombin essential for substrate and cofactor recognition in the prothrombinase complex S Yegneswaran, RM Mesters, JH Griffin Journal of Biological Chemistry 278 (35), 33312-33318, 2003 | 46 | 2003 |
| Conformational changes in activated protein C caused by binding of the first epidermal growth factor-like module of protein S TM HACKENG, S YEGNESWARAN, AE JOHNSON, JH GRIFFIN Biochemical Journal 349 (3), 757-764, 2000 | 37 | 2000 |
| Topological studies of the amino terminal modules of vitamin K-dependent protein S using monoclonal antibody epitope mapping and molecular modeling TK Giri, BO Villoutreix, A Wallqvist, B Dahlbäck, PG de Frutos Thrombosis and haemostasis 80 (11), 798-804, 1998 | 32 | 1998 |
| Characterization of a factor Xa binding site on factor Va near the Arg-506 activated protein C cleavage site AJ Gale, S Yegneswaran, X Xu, JL Pellequer, JH Griffin Journal of Biological Chemistry 282 (30), 21848-21855, 2007 | 31 | 2007 |
| Prothrombin residues 473–487 contribute to factor Va binding in the prothrombinase complex S Yegneswaran, RM Mesters, JA Fernández, JH Griffin Journal of Biological Chemistry 279 (47), 49019-49025, 2004 | 31 | 2004 |
| C4b-binding protein inhibits the factor V-dependent but not the factor V-independent cofactor activity of protein S in the activated protein C-mediated inactivation of factor VIIIa RHL van de Poel, JCM Meijers, BN Bouma Thrombosis and haemostasis 85 (05), 761-765, 2001 | 31 | 2001 |
| Glucosylceramide, a neutral glycosphingolipid anticoagulant cofactor, enhances the interaction of human-and bovine-activated protein C with negatively charged phospholipid vesicles S Yegneswaran, H Deguchi, JH Griffin Journal of Biological Chemistry 278 (17), 14614-14621, 2003 | 29 | 2003 |
| Raising the active site of factor VIIa above the membrane surface reduces its procoagulant activity but not factor VII autoactivation EK Waters, S Yegneswaran, JH Morrissey Journal of biological chemistry 281 (36), 26062-26068, 2006 | 26 | 2006 |
| Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia XY Zhao, A Wilmen, D Wang, X Wang, M Bauzon, JY Kim, L Linden, L Li, ... Nature Communications 11 (1), 2992, 2020 | 25 | 2020 |
| Factor Va increases the affinity of factor Xa for prothrombin: a binding study using a novel photoactivable thiol-specific fluorescent probe S Yegneswaran, JA Fernández, JH Griffin, PE Dawson Chemistry & biology 9 (4), 485-494, 2002 | 21 | 2002 |
| The thrombin-sensitive region of protein S mediates phospholipid-dependent interaction with factor Xa S Yegneswaran, TM Hackeng, PE Dawson, JH Griffin Journal of biological chemistry 283 (48), 33046-33052, 2008 | 20 | 2008 |
| FRET studies with factor X mutants provide insight into the topography of the membrane-bound factor X/Xa SH Qureshi, L Yang, S Yegneswaran, AR Rezaie Biochemical Journal 407 (3), 427-433, 2007 | 20 | 2007 |
