| An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain JP Xiong, R Li, M Essafi, T Stehle, MA Arnaout Journal of Biological Chemistry 275 (49), 38762-38767, 2000 | 187 | 2000 |
| Does the integrin αA domain act as a ligand for its βA domain? JL Alonso, M Essafi, JP Xiong, T Stehle, MA Arnaout Current Biology 12 (10), R340-R342, 2002 | 138 | 2002 |
| Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-κB, p38MAPK and Akt inhibition K Essafi-Benkhadir, A Refai, I Riahi, S Fattouch, H Karoui, M Essafi Biochemical and biophysical research communications 418 (1), 180-185, 2012 | 129 | 2012 |
| Polycystin-1 activates and stabilizes the polycystin-2 channel GM Xu, S González-Perrett, M Essafi, GA Timpanaro, N Montalbetti, ... Journal of Biological Chemistry 278 (3), 1457-1462, 2003 | 123 | 2003 |
| Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a M Ticchioni, M Essafi, PY Jeandel, F Davi, JP Cassuto, M Deckert, ... Oncogene 26 (50), 7081-7091, 2007 | 120 | 2007 |
| The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells I Riahi-Chebbi, S Souid, H Othman, M Haoues, H Karoui, A Morel, ... Scientific reports 9 (1), 195, 2019 | 113 | 2019 |
| Mycobacterium tuberculosis Virulent Factor ESAT-6 Drives Macrophage Differentiation Toward the Pro-inflammatory M1 Phenotype and Subsequently Switches It … A Refai, S Gritli, MR Barbouche, M Essafi Frontiers in cellular and infection microbiology 8, 327, 2018 | 102 | 2018 |
| Voltage dependence and pH regulation of human polycystin-2-mediated cation channel activity S González-Perrett, M Batelli, K Kim, M Essafi, G Timpanaro, N Moltabetti, ... Journal of Biological Chemistry 277 (28), 24959-24966, 2002 | 96 | 2002 |
| Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor‐induced angiogenesis through cell cycle arrest, apoptosis induction and … O Zakraoui, C Marcinkiewicz, Z Aloui, H Othman, R Grépin, M Haoues, ... Molecular carcinogenesis 56 (1), 18-35, 2017 | 74 | 2017 |
| Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness K Essafi-Benkhadir, S Grosso, A Puissant, G Robert, M Essafi, M Deckert, ... PloS one 4 (2), e4478, 2009 | 46 | 2009 |
| Two distinct conformational states of Mycobacterium tuberculosis virulent factor early secreted antigenic target 6 kDa are behind the discrepancy around its biological functions A Refai, M Haoues, H Othman, MR Barbouche, P Moua, A Bondon, ... The FEBS journal 282 (21), 4114-4129, 2015 | 45 | 2015 |
| Forkhead box O 3 (FOXO 3) transcription factor mediates apoptosis in BCG‐infected macrophages M Haoues, A Refai, A Mallavialle, MR Barbouche, N Laabidi, M Deckert, ... Cellular microbiology 16 (9), 1378-1390, 2014 | 41 | 2014 |
| Detection of ESAT-6 by a label free miniature immuno-electrochemical biosensor as a diagnostic tool for tuberculosis MF Diouani, O Ouerghi, A Refai, K Belgacem, C Tlili, D Laouini, M Essafi Materials Science and Engineering: C 74, 465-470, 2017 | 40 | 2017 |
| Cell-penetrating TAT-FOXO3 fusion proteins induce apoptotic cell death in leukemic cells M Essafi, AD Baudot, X Mouska, JP Cassuto, M Ticchioni, M Deckert Molecular cancer therapeutics 10 (1), 37-46, 2011 | 34 | 2011 |
| FOXO3 transcription factor regulates IL-10 expression in mycobacteria-infected macrophages, tuning their polarization and the subsequent adaptive immune response R Bouzeyen, M Haoues, MR Barbouche, R Singh, M Essafi Frontiers in Immunology 10, 480516, 2019 | 33 | 2019 |
| NU-6027 inhibits growth of Mycobacterium tuberculosis by targeting protein kinase D and protein kinase G S Kidwai, R Bouzeyen, S Chakraborti, N Khare, S Das, T Priya Gosain, ... Antimicrobial agents and chemotherapy 63 (9), 10.1128/aac. 00996-19, 2019 | 30 | 2019 |
| Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy I Riahi-Chebbi, M Haoues, M Essafi, O Zakraoui, S Fattouch, H Karoui, ... Cancer Cell International 16, 1-15, 2015 | 29 | 2015 |
| Ultrasensitive detection of hazardous reactive oxygen species using flexible organic transistors with polyphenol-embedded conjugated polymer sensing layers J Jeong, M Essafi, C Lee, M Haoues, MF Diouani, H Kim, Y Kim Journal of hazardous materials 355, 17-24, 2018 | 25 | 2018 |
| Role of the β-subunit arginine/lysine finger in integrin heterodimer formation and function V Gupta, JL Alonso, T Sugimori, M Issafi, JP Xiong, MA Arnaout The Journal of Immunology 180 (3), 1713-1718, 2008 | 21 | 2008 |
| Use of Taguchi's methods as a basis to optimize hybridoma cell line growth and antibody production in a spinner flask H Kallel, H Zaïri, S Rourou, M Essafi, R Barbouche, K Dellagi, ... Cytotechnology 39, 9-14, 2002 | 21 | 2002 |
