Professor Anna L Gloyn
Professor Anna L Gloyn
Verified email at drl.ox.ac.uk
TitleCited byYear
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ...
Nature genetics 42 (2), 105, 2010
18722010
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
BF Voight, LJ Scott, V Steinthorsdottir, AP Morris, C Dina, RP Welch, ...
Nature genetics 42 (7), 579, 2010
17222010
Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6. 2 and permanent neonatal diabetes
AL Gloyn, ER Pearson, JF Antcliff, P Proks, GJ Bruining, AS Slingerland, ...
New England Journal of Medicine 350 (18), 1838-1849, 2004
11632004
Large-scale association studies of variants in genes encoding the pancreatic β-cell KATP channel subunits Kir6. 2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant …
AL Gloyn, MN Weedon, KR Owen, MJ Turner, BA Knight, G Hitman, ...
Diabetes 52 (2), 568-572, 2003
8752003
The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ...
Nature 536 (7614), 41-47, 2016
6412016
Parental origin of sequence variants associated with complex diseases
A Kong, V Steinthorsdottir, G Masson, G Thorleifsson, P Sulem, ...
Nature 462 (7275), 868-874, 2009
5122009
Mutations in PTF1A cause pancreatic and cerebellar agenesis
GS Sellick, KT Barker, I Stolte-Dijkstra, C Fleischmann, RJ Coleman, ...
Nature genetics 36 (12), 1301-1305, 2004
3982004
Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6. 2: patient characteristics and initial response to sulfonylurea therapy
JV Sagen, H Ræder, E Hathout, N Shehadeh, K Gudmundsson, H Bævre, ...
Diabetes 53 (10), 2713-2718, 2004
3922004
Update on mutations in glucokinase (GCK), which cause maturity‐onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia
KK Osbak, K Colclough, C Saint‐Martin, NL Beer, C Bellanné‐Chantelot, ...
Human mutation 30 (11), 1512-1526, 2009
3522009
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
L Pasquali, KJ Gaulton, SA Rodríguez-Seguí, L Mularoni, ...
Nature genetics 46 (2), 136-143, 2014
3372014
Mutations in ATP-sensitive K+ channel genes cause transient neonatal diabetes and permanent diabetes in childhood or adulthood
SE Flanagan, AM Patch, DJG Mackay, EL Edghill, AL Gloyn, D Robinson, ...
Diabetes 56 (7), 1930-1937, 2007
3332007
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
RJ Strawbridge, J Dupuis, I Prokopenko, A Barker, E Ahlqvist, D Rybin, ...
Diabetes 60 (10), 2624-2634, 2011
3102011
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes
I Morán, İ Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ...
Cell metabolism 16 (4), 435-448, 2012
3012012
Glucokinase (GCK) mutations in hyper‐ and hypoglycemia: Maturity‐onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy
AL Gloyn
Human mutation 22 (5), 353-362, 2003
2942003
The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in …
NL Beer, ND Tribble, LJ McCulloch, C Roos, PRV Johnson, ...
Human molecular genetics 18 (21), 4081-4088, 2009
2732009
Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes
BM Herrera, HE Lockstone, JM Taylor, M Ria, A Barrett, S Collins, ...
Diabetologia 53 (6), 1099-1109, 2010
2672010
Molecular basis of Kir6. 2 mutations associated with neonatal diabetes or neonatal diabetes plus neurological features
P Proks, JF Antcliff, J Lippiat, AL Gloyn, AT Hattersley, FM Ashcroft
Proceedings of the National Academy of Sciences 101 (50), 17539-17544, 2004
2452004
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, ...
Nature genetics 47 (12), 1415-1425, 2015
2392015
Update of mutations in the genes encoding the pancreatic beta‐cell KATP channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes …
SE Flanagan, S Clauin, C Bellanné‐Chantelot, P de Lonlay, LW Harries, ...
Human mutation 30 (2), 170-180, 2009
2292009
Mutations in KCNJ11, which encodes Kir6. 2, are a common cause of diabetes diagnosed in the first 6 months of life, with the phenotype determined by genotype
SE Flanagan, EL Edghill, AL Gloyn, S Ellard, AT Hattersley
Diabetologia 49 (6), 1190-1197, 2006
2212006
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