Fabian Fröhlich
Fabian Fröhlich
Laboratory of Systems Pharmacology, Harvard Medical School
Bestätigte E-Mail-Adresse bei hms.harvard.edu - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Scalable parameter estimation for genome-scale biochemical reaction networks
F Fröhlich, B Kaltenbacher, FJ Theis, J Hasenauer
PLoS computational biology 13 (1), e1005331, 2017
852017
Inference for stochastic chemical kinetics using moment equations and system size expansion
F Fröhlich, P Thomas, A Kazeroonian, FJ Theis, R Grima, J Hasenauer
PLoS computational biology 12 (7), e1005030, 2016
552016
PESTO: Parameter EStimation TOolbox
P Stapor, D Weindl, B Ballnus, S Hug, C Loos, A Fiedler, S Krause, ...
Bioinformatics, 2017
522017
Efficient Parameter Estimation Enables the Prediction of Drug Response Using a Mechanistic Pan-Cancer Pathway Model
F Fröhlich, T Kessler, D Weindl, A Shadrin, L Schmiester, H Hache, ...
Cell Systems, 2018
47*2018
Benchmarking optimization methods for parameter estimation in large kinetic models
AF Villaverde, F Fröhlich, D Weindl, J Hasenauer, JR Banga
Bioinformatics 35 (5), 830-838, 2019
392019
CERENA: ChEmical REaction Network Analyzer—a toolbox for the simulation and analysis of stochastic chemical kinetics
A Kazeroonian, F Fröhlich, A Raue, FJ Theis, J Hasenauer
PloS one 11 (1), e0146732, 2016
382016
GenSSI 2.0: Multi-experiment structural identifiability analysis of SBML models
TS Ligon, F Fröhlich, OT Chi, JR Banga, E Balsa-Canto, J Hasenauer
Bioinformatics, 2017
352017
Uncertainty Analysis for Non-identifiable Dynamical Systems: Profile Likelihoods, Bootstrapping and More
F Fröhlich, FJ Theis, J Hasenauer
Computational Methods in Systems Biology 8859, 61-72, 2014
342014
Parameter estimation for dynamical systems with discrete events and logical operations
F Fröhlich, FJ Theis, JO Rädler, J Hasenauer
Bioinformatics 33 (7), 1049-1056, 2017
272017
Sparse control of force field dynamics
M Bongini, M Fornasier, F Frcöhlich, L Haghverdi
2014 7th International Conference on NETwork Games, COntrol and OPtimization …, 2014
25*2014
A Hierarchical, Data-Driven Approach to Modeling Single-Cell Populations Predicts Latent Causes of Cell-To-Cell Variability
C Loos, K Moeller, F Fröhlich, T Hucho, J Hasenauer
Cell systems 6 (5), 593-603. e13, 2018
182018
Scalable inference of ordinary differential equation models of biochemical processes
F Fröhlich, C Loos, J Hasenauer
Gene Regulatory Networks, 385-422, 2019
102019
Multi-experiment nonlinear mixed effect modeling of single-cell translation kinetics after transfection
F Fröhlich, A Reiser, L Fink, D Woschée, T Ligon, FJ Theis, JO Rädler, ...
NPJ systems biology and applications 4 (1), 1-12, 2018
92018
Optimization and profile calculation of ODE models using second order adjoint sensitivity analysis
P Stapor, F Fröhlich, J Hasenauer
Bioinformatics 34 (13), i151-i159, 2018
8*2018
Design and Characterization of a Modular Membrane Protein Anchor to Functionalize the Moss Physcomitrella patens with Extracellular Catalytic and/or Binding Activities
V Morath, DJJ Truong, F Albrecht, I Polte, RA Ciccone, LF Funke, ...
ACS Synthetic Biology 3 (12), 990–994, 2014
62014
Efficient parameterization of large-scale dynamic models based on relative measurements
L Schmiester, Y Schälte, F Fröhlich, J Hasenauer, D Weindl
Bioinformatics 36 (2), 594-602, 2020
52020
Radial Basis Function Approximations of Bayesian Parameter Posterior Densities for Uncertainty Analysis
F Fröhlich, S Hross, FJ Theis, J Hasenauer
Computational Methods in Systems Biology 8859, 73-85, 2014
52014
Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells
L Gerosa, C Chidley, F Fröhlich, G Sanchez, SK Lim, J Muhlich, JY Chen, ...
Cell Systems, 2020
3*2020
PEtab--interoperable specification of parameter estimation problems in systems biology
L Schmiester, Y Schälte, FT Bergmann, T Camba, E Dudkin, J Egert, ...
arXiv preprint arXiv:2004.01154, 2020
32020
Scalable Simulation and Optimization Methods for Differential Equation Models describing Biochemical Reaction Networks
F Fröhlich
Technische Universität München, 2018
12018
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