Christian J. Braun
Christian J. Braun
Pediatrician & Max Eder Group leader at LMU Munich
Verified email at - Homepage
Cited by
Cited by
Gene therapy for Wiskott-Aldrich syndrome—long-term efficacy and genotoxicity
CJ Braun, K Boztug, A Paruzynski, M Witzel, A Schwarzer, M Rothe, ...
Science translational medicine 6 (227), 227ra33-227ra33, 2014
p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest
CJ Braun, X Zhang, I Savelyeva, S Wolff, UM Moll, T Schepeler, TF Ørntoft, ...
Cancer research 68 (24), 10094-10104, 2008
Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome
D Kotlarz, N Ziętara, G Uzel, T Weidemann, CJ Braun, J Diestelhorst, ...
Journal of Experimental Medicine 210 (3), 433-443, 2013
Coordinated splicing of regulatory detained introns within oncogenic transcripts creates an exploitable vulnerability in malignant glioma
CJ Braun, M Stanciu, PL Boutz, JC Patterson, D Calligaris, F Higuchi, ...
Cancer cell 32 (4), 411-426. e11, 2017
Sensitizing protective tumor microenvironments to antibody-mediated therapy
CP Pallasch, I Leskov, CJ Braun, D Vorholt, A Drake, YM Soto-Feliciano, ...
Cell 156 (3), 590-602, 2014
Minor changes in expression of the mismatch repair protein MSH2 exert a major impact on glioblastoma response to temozolomide
JL McFaline-Figueroa, CJ Braun, M Stanciu, ZD Nagel, P Mazzucato, ...
Cancer research 75 (15), 3127-3138, 2015
A role for PVRL4-driven cell–cell interactions in tumorigenesis
NN Pavlova, C Pallasch, AEH Elia, CJ Braun, TF Westbrook, M Hemann, ...
Elife 2, e00358, 2013
Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation
CJ Braun, PM Bruno, MA Horlbeck, LA Gilbert, JS Weissman, MT Hemann
Proceedings of the National Academy of Sciences 113 (27), E3892-E3900, 2016
A pleiotropic RNA-binding protein controls distinct cell cycle checkpoints to drive resistance of p53-defective tumors to chemotherapy
IG Cannell, KA Merrick, S Morandell, CQ Zhu, CJ Braun, RA Grant, ...
Cancer cell 28 (5), 623-637, 2015
In vivo functional screening for systems-level integrative cancer genomics
J Weber, CJ Braun, D Saur, R Rad
Nature reviews Cancer 20 (10), 573-593, 2020
Gene therapy for Wiskott-Aldrich syndrome—long-term reconstitution and clinical benefits, but increased risk for leukemogenesis
CJ Braun, M Witzel, A Paruzynski, K Boztug, C Kalle, M Schmidt, C Klein
Rare diseases 2 (1), e947749, 2014
Cell cycle arrest or apoptosis by p53: are microRNAs-192/215 and-34 making the decision?
SA Georges, BN Chau, CJ Braun, X Zhang, M Dobbelstein
Cell Cycle 8 (5), 677-682, 2009
CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver
T Kaltenbacher, J Löprich, R Maresch, J Weber, S Müller, R Oellinger, ...
Nature Protocols 17 (4), 1142-1188, 2022
Tutorial: design and execution of CRISPR in vivo screens
CJ Braun, AC Adames, D Saur, R Rad
Nature Protocols 17 (9), 1903-1925, 2022
Epigenetic drug screening defines a PRMT5 inhibitor–sensitive pancreatic cancer subtype
F Orben, K Lankes, C Schneeweis, Z Hassan, H Jakubowsky, L Krauß, ...
JCI insight 7 (10), 2022
A Raf-competitive K-ras binder can fail to functionally antagonize signaling
MJ Kauke, AW Tisdale, RL Kelly, CJ Braun, MT Hemann, KD Wittrup
Molecular Cancer Therapeutics 17 (8), 1773-1780, 2018
CLUE: a bioinformatic and wet-lab pipeline for multiplexed cloning of custom sgRNA libraries
M Becker, H Noll-Puchta, D Amend, F Nolte, C Fuchs, I Jeremias, ...
Nucleic acids research 48 (13), e78-e78, 2020
Efficacy of gene therapy for Wiskott-Aldrich-syndrome
CJ Braun, K Boztug, M Schmidt, MH Albert, A Schwarzer, A Paruzynski, ...
Blood, The Journal of the American Society of Hematology 118 (21), 165-165, 2011
High-level clustering of vector integrations in the German WAS clinical gene therapy trial
A Paruzynski, K Boztug, C Ball, A Nowrouzi, A Arens, C Lulay, M Dorda, ...
MOLECULAR THERAPY 20, S212-S212, 2012
Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia
P Horak, S Uhrig, M Witzel, I Gil-Farina, B Hutter, T Rath, L Gieldon, ...
Leukemia 34 (10), 2785-2789, 2020
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