| Gene therapy for Wiskott-Aldrich syndrome—long-term efficacy and genotoxicity CJ Braun, K Boztug, A Paruzynski, M Witzel, A Schwarzer, M Rothe, ... Science translational medicine 6 (227), 227ra33-227ra33, 2014 | 645 | 2014 |
| p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest CJ Braun, X Zhang, I Savelyeva, S Wolff, UM Moll, T Schepeler, TF Ørntoft, ... Cancer research 68 (24), 10094-10104, 2008 | 566 | 2008 |
| Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome D Kotlarz, N Ziętara, G Uzel, T Weidemann, CJ Braun, J Diestelhorst, ... Journal of Experimental Medicine 210 (3), 433-443, 2013 | 237 | 2013 |
| Coordinated splicing of regulatory detained introns within oncogenic transcripts creates an exploitable vulnerability in malignant glioma CJ Braun, M Stanciu, PL Boutz, JC Patterson, D Calligaris, F Higuchi, ... Cancer cell 32 (4), 411-426. e11, 2017 | 211 | 2017 |
| Sensitizing protective tumor microenvironments to antibody-mediated therapy CP Pallasch, I Leskov, CJ Braun, D Vorholt, A Drake, YM Soto-Feliciano, ... Cell 156 (3), 590-602, 2014 | 200 | 2014 |
| Minor changes in expression of the mismatch repair protein MSH2 exert a major impact on glioblastoma response to temozolomide JL McFaline-Figueroa, CJ Braun, M Stanciu, ZD Nagel, P Mazzucato, ... Cancer research 75 (15), 3127-3138, 2015 | 136 | 2015 |
| A role for PVRL4-driven cell–cell interactions in tumorigenesis NN Pavlova, C Pallasch, AEH Elia, CJ Braun, TF Westbrook, M Hemann, ... Elife 2, e00358, 2013 | 125 | 2013 |
| Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation CJ Braun, PM Bruno, MA Horlbeck, LA Gilbert, JS Weissman, MT Hemann Proceedings of the National Academy of Sciences 113 (27), E3892-E3900, 2016 | 114 | 2016 |
| A pleiotropic RNA-binding protein controls distinct cell cycle checkpoints to drive resistance of p53-defective tumors to chemotherapy IG Cannell, KA Merrick, S Morandell, CQ Zhu, CJ Braun, RA Grant, ... Cancer cell 28 (5), 623-637, 2015 | 92 | 2015 |
| In vivo functional screening for systems-level integrative cancer genomics J Weber, CJ Braun, D Saur, R Rad Nature reviews Cancer 20 (10), 573-593, 2020 | 56 | 2020 |
| Gene therapy for Wiskott-Aldrich syndrome—long-term reconstitution and clinical benefits, but increased risk for leukemogenesis CJ Braun, M Witzel, A Paruzynski, K Boztug, C Kalle, M Schmidt, C Klein Rare diseases 2 (1), e947749, 2014 | 39 | 2014 |
| Cell cycle arrest or apoptosis by p53: are microRNAs-192/215 and-34 making the decision? SA Georges, BN Chau, CJ Braun, X Zhang, M Dobbelstein Cell Cycle 8 (5), 677-682, 2009 | 21 | 2009 |
| CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver T Kaltenbacher, J Löprich, R Maresch, J Weber, S Müller, R Oellinger, ... Nature Protocols 17 (4), 1142-1188, 2022 | 19 | 2022 |
| Tutorial: design and execution of CRISPR in vivo screens CJ Braun, AC Adames, D Saur, R Rad Nature Protocols 17 (9), 1903-1925, 2022 | 16 | 2022 |
| Epigenetic drug screening defines a PRMT5 inhibitor–sensitive pancreatic cancer subtype F Orben, K Lankes, C Schneeweis, Z Hassan, H Jakubowsky, L Krauß, ... JCI insight 7 (10), 2022 | 16 | 2022 |
| A Raf-competitive K-Ras binder can fail to functionally antagonize signaling MJ Kauke, AW Tisdale, RL Kelly, CJ Braun, MT Hemann, KD Wittrup Molecular Cancer Therapeutics 17 (8), 1773-1780, 2018 | 10 | 2018 |
| CLUE: a bioinformatic and wet-lab pipeline for multiplexed cloning of custom sgRNA libraries M Becker, H Noll-Puchta, D Amend, F Nolte, C Fuchs, I Jeremias, ... Nucleic acids research 48 (13), e78-e78, 2020 | 9 | 2020 |
| Efficacy of gene therapy for Wiskott-Aldrich-syndrome CJ Braun, K Boztug, M Schmidt, MH Albert, A Schwarzer, A Paruzynski, ... Blood, The Journal of the American Society of Hematology 118 (21), 165-165, 2011 | 7 | 2011 |
| High-level clustering of vector integrations in the German WAS clinical gene therapy trial A Paruzynski, K Boztug, C Ball, A Nowrouzi, A Arens, C Lulay, M Dorda, ... MOLECULAR THERAPY 20, S212-S212, 2012 | 6 | 2012 |
| Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia P Horak, S Uhrig, M Witzel, I Gil-Farina, B Hutter, T Rath, L Gieldon, ... Leukemia 34 (10), 2785-2789, 2020 | 5 | 2020 |
Christian PallaschProfessor at University Hospital of CologneVerified email at uk-koeln.de
