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jaiprakash sharma
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Lysosome biogenesis in health and disease
L Bajaj, P Lotfi, R Pal, A Ronza, J Sharma, M Sardiello
Journal of neurochemistry 148 (5), 573-589, 2019
1312019
E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity
A Mishra, P Dikshit, S Purkayastha, J Sharma, N Nukina, NR Jana
Journal of biological chemistry 283 (12), 7648-7656, 2008
1012008
CLN8 is an endoplasmic reticulum cargo receptor that regulates lysosome biogenesis
A di Ronza, L Bajaj, J Sharma, D Sanagasetti, P Lotfi, CJ Adamski, ...
Nature cell biology 20 (12), 1370-1377, 2018
922018
The ubiquitin ligase E6‐AP promotes degradation of α‐synuclein
SA Mulherkar, J Sharma, NR Jana
Journal of neurochemistry 110 (6), 1955-1964, 2009
752009
Sequestration of chaperones and proteasome into Lafora bodies and proteasomal dysfunction induced by Lafora disease-associated mutations of malin
SNR Rao, R Maity, J Sharma, P Dey, SK Shankar, P Satishchandra, ...
Human molecular genetics 19 (23), 4726-4734, 2010
652010
A CLN6-CLN8 complex recruits lysosomal enzymes at the ER for Golgi transfer
L Bajaj, J Sharma, A di Ronza, P Zhang, A Eblimit, R Pal, D Roman, ...
The Journal of clinical investigation 130 (8), 4118-4132, 2020
622020
Capsaicin induces apoptosis through ubiquitin–proteasome system dysfunction
R Maity, J Sharma, NR Jana
Journal of cellular biochemistry 109 (5), 933-942, 2010
542010
NADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson’s disease
R Pal, L Bajaj, J Sharma, M Palmieri, A Di Ronza, P Lotfi, A Chaudhury, ...
Scientific reports 6 (1), 22866, 2016
502016
Malin regulates Wnt signaling pathway through degradation of dishevelled2
J Sharma, S Mulherkar, D Mukherjee, NR Jana
Journal of Biological Chemistry 287 (9), 6830-6839, 2012
492012
Neuronatin-mediated aberrant calcium signaling and endoplasmic reticulum stress underlie neuropathology in Lafora disease
J Sharma, D Mukherjee, SNR Rao, S Iyengar, SK Shankar, ...
Journal of Biological Chemistry 288 (13), 9482-9490, 2013
482013
Co-chaperone CHIP stabilizes aggregate-prone malin, a ubiquitin ligase mutated in Lafora disease
SNR Rao, J Sharma, R Maity, NR Jana
Journal of biological chemistry 285 (2), 1404-1413, 2010
442010
Lysosomes and brain health
J Sharma, A Di Ronza, P Lotfi, M Sardiello
Annual review of neuroscience 41, 255-276, 2018
432018
Lafora disease ubiquitin ligase malin promotes proteasomal degradation of neuronatin and regulates glycogen synthesis
J Sharma, SNR Rao, SK Shankar, P Satishchandra, NR Jana
Neurobiology of disease 44 (1), 133-141, 2011
432011
Identification of a peptide inhibitor of the RPM-1· FSN-1 ubiquitin ligase complex
J Sharma, ST Baker, SM Turgeon, AM Gurney, KJ Opperman, B Grill
Journal of Biological Chemistry 289 (50), 34654-34666, 2014
192014
Calpain activity is negatively regulated by a KCTD7–Cullin-3 complex via non-degradative ubiquitination
J Sharma, S Mulherkar, UI Chen, Y Xiong, L Bajaj, BK Cho, YA Goo, ...
Cell Discovery 9 (1), 32, 2023
22023
TFEB degradation is regulated by an IKK/β-TrCP2 phosphorylation-ubiquitination cascade
Y Xiong
Washington University in St. Louis, 2023
2023
Bowel dysmotility and enteric neuron degeneration in lysosomal storage disease mice is prevented by gene therapy
MJ Jansen, LL Williams, S Wang, EM Eultgen, K Takahashi, HR Nelvagal, ...
bioRxiv, 2023.05. 26.542524, 2023
2023
A Study to Assess the Existing Cultural Beliefs and Associate Practices Regarding Newborn Care Among Mothers in Chandu Village at Gurugram, Haryana
K Pooja, P Sharma, N Rohilla, D Mukherjee, J Sharma
IDENTIFICATION AND CHARACTERIZATION OF SUBSTRATES OF MALIN AN E3 LIGASE MUTATED IN LAFORA PROGRESSIVE MYOCLONUS EPILEPSY
J Sharma
Gurugram, 0
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