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jaiprakash sharma
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Lysosome biogenesis in health and disease
L Bajaj, P Lotfi, R Pal, A Ronza, J Sharma, M Sardiello
Journal of neurochemistry 148 (5), 573-589, 2019
1362019
E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity
A Mishra, P Dikshit, S Purkayastha, J Sharma, N Nukina, NR Jana
Journal of Biological Chemistry 283 (12), 7648-7656, 2008
1022008
CLN8 is an endoplasmic reticulum cargo receptor that regulates lysosome biogenesis
A di Ronza, L Bajaj, J Sharma, D Sanagasetti, P Lotfi, CJ Adamski, ...
Nature cell biology 20 (12), 1370-1377, 2018
952018
The ubiquitin ligase E6‐AP promotes degradation of α‐synuclein
SA Mulherkar, J Sharma, NR Jana
Journal of neurochemistry 110 (6), 1955-1964, 2009
782009
A CLN6-CLN8 complex recruits lysosomal enzymes at the ER for Golgi transfer
L Bajaj, J Sharma, A di Ronza, P Zhang, A Eblimit, R Pal, D Roman, ...
The Journal of clinical investigation 130 (8), 4118-4132, 2020
672020
Sequestration of chaperones and proteasome into Lafora bodies and proteasomal dysfunction induced by Lafora disease-associated mutations of malin
SNR Rao, R Maity, J Sharma, P Dey, SK Shankar, P Satishchandra, ...
Human molecular genetics 19 (23), 4726-4734, 2010
662010
Capsaicin induces apoptosis through ubiquitin–proteasome system dysfunction
R Maity, J Sharma, NR Jana
Journal of cellular biochemistry 109 (5), 933-942, 2010
532010
NADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson’s disease
R Pal, L Bajaj, J Sharma, M Palmieri, A Di Ronza, P Lotfi, A Chaudhury, ...
Scientific reports 6 (1), 22866, 2016
502016
Neuronatin-mediated aberrant calcium signaling and endoplasmic reticulum stress underlie neuropathology in Lafora disease
J Sharma, D Mukherjee, SNR Rao, S Iyengar, SK Shankar, ...
Journal of Biological Chemistry 288 (13), 9482-9490, 2013
502013
Malin regulates Wnt signaling pathway through degradation of dishevelled2
J Sharma, S Mulherkar, D Mukherjee, NR Jana
Journal of Biological Chemistry 287 (9), 6830-6839, 2012
482012
Lysosomes and brain health
J Sharma, A Di Ronza, P Lotfi, M Sardiello
Annual review of neuroscience 41 (1), 255-276, 2018
452018
Co-chaperone CHIP stabilizes aggregate-prone malin, a ubiquitin ligase mutated in Lafora disease
SNR Rao, J Sharma, R Maity, NR Jana
Journal of Biological Chemistry 285 (2), 1404-1413, 2010
452010
Lafora disease ubiquitin ligase malin promotes proteasomal degradation of neuronatin and regulates glycogen synthesis
J Sharma, SNR Rao, SK Shankar, P Satishchandra, NR Jana
Neurobiology of disease 44 (1), 133-141, 2011
432011
Identification of a peptide inhibitor of the RPM-1· FSN-1 ubiquitin ligase complex
J Sharma, ST Baker, SM Turgeon, AM Gurney, KJ Opperman, B Grill
Journal of Biological Chemistry 289 (50), 34654-34666, 2014
192014
Calpain activity is negatively regulated by a KCTD7–Cullin-3 complex via non-degradative ubiquitination
J Sharma, S Mulherkar, UI Chen, Y Xiong, L Bajaj, BK Cho, YA Goo, ...
Cell Discovery 9 (1), 32, 2023
22023
D-mannose as a new therapy for fucokinase deficiency-related congenital disorder of glycosylation (FCSK-CDG)
RT Starosta, AJ Lee, ER Toolan, M He, P Wongkittichote, EJP Daniel, ...
Molecular genetics and metabolism, 108488, 2024
2024
Bowel dysmotility and enteric neuron degeneration in lysosomal storage disease mice is prevented by gene therapy
MJ Jansen, LL Williams, SH Wang, EM Eultgen, K Takahashi, ...
bioRxiv, 2023.05. 26.542524, 2023
2023
TFEB degradation is regulated by an IKK/β-TrCP2 phosphorylation-ubiquitination cascade
Y Xiong
Washington University in St. Louis, 2023
2023
A Study to Assess the Existing Cultural Beliefs and Associate Practices Regarding Newborn Care Among Mothers in Chandu Village at Gurugram, Haryana
K Pooja, P Sharma, N Rohilla, D Mukherjee, J Sharma
IDENTIFICATION AND CHARACTERIZATION OF SUBSTRATES OF MALIN AN E3 LIGASE MUTATED IN LAFORA PROGRESSIVE MYOCLONUS EPILEPSY
J Sharma
Gurugram, 0
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