| Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche F Arai, A Hirao, M Ohmura, H Sato, S Matsuoka, K Takubo, K Ito, GY Koh, ... Cell 118 (2), 149-161, 2004 | 2487 | 2004 |
| Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells K Ito, A Hirao, F Arai, K Takubo, S Matsuoka, K Miyamoto, M Ohmura, ... Nature medicine 12 (4), 446-451, 2006 | 1527 | 2006 |
| Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells K Ito, A Hirao, F Arai, S Matsuoka, K Takubo, I Hamaguchi, K Nomiyama, ... Nature 431 (7011), 997-1002, 2004 | 1359 | 2004 |
| Metabolic requirements for the maintenance of self-renewing stem cells K Ito, T Suda Nature reviews Molecular cell biology 15 (4), 243-256, 2014 | 1069 | 2014 |
| Regulation of the HIF-1α level is essential for hematopoietic stem cells K Takubo, N Goda, W Yamada, H Iriuchishima, E Ikeda, Y Kubota, ... Cell stem cell 7 (3), 391-402, 2010 | 1019 | 2010 |
| DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells M Yagi, T Miyamoto, Y Sawatani, K Iwamoto, N Hosogane, N Fujita, ... The Journal of experimental medicine 202 (3), 345-351, 2005 | 1010 | 2005 |
| Foxo3a is essential for maintenance of the hematopoietic stem cell pool K Miyamoto, KY Araki, K Naka, F Arai, K Takubo, S Yamazaki, S Matsuoka, ... Cell stem cell 1 (1), 101-112, 2007 | 983 | 2007 |
| Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche H Yoshihara, F Arai, K Hosokawa, T Hagiwara, K Takubo, Y Nakamura, ... Cell stem cell 1 (6), 685-697, 2007 | 948 | 2007 |
| Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow S Morikawa, Y Mabuchi, Y Kubota, Y Nagai, K Niibe, E Hiratsu, S Suzuki, ... Journal of Experimental Medicine 206 (11), 2483-2496, 2009 | 947 | 2009 |
| Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis C Zhao, N Irie, Y Takada, K Shimoda, T Miyamoto, T Nishiwaki, T Suda, ... Cell metabolism 4 (2), 111-121, 2006 | 941 | 2006 |
| Metabolic regulation of hematopoietic stem cells in the hypoxic niche T Suda, K Takubo, GL Semenza Cell stem cell 9 (4), 298-310, 2011 | 892 | 2011 |
| Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor κB (RANK) receptors F Arai, T Miyamoto, O Ohneda, T Inada, T Sudo, K Brasel, T Miyata, ... The Journal of experimental medicine 190 (12), 1741-1754, 1999 | 858 | 1999 |
| Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells K Takubo, G Nagamatsu, CI Kobayashi, A Nakamura-Ishizu, H Kobayashi, ... Cell stem cell 12 (1), 49-61, 2013 | 816 | 2013 |
| A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance K Ito, A Carracedo, D Weiss, F Arai, U Ala, DE Avigan, ZT Schafer, ... Nature medicine 18 (9), 1350-1358, 2012 | 715 | 2012 |
| Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. Y Yamaguchi, T Suda, J Suda, M Eguchi, Y Miura, N Harada, A Tominaga, ... The Journal of experimental medicine 167 (1), 43-56, 1988 | 700 | 1988 |
| In vivo and in vitro stem cell function of c-kit-and Sca-1-positive murine hematopoietic cells S Okada, H Nakauchi, K Nagayoshi, S Nishikawa, Y Miura, T Suda | 690 | 1992 |
| A role for hematopoietic stem cells in promoting angiogenesis N Takakura, T Watanabe, S Suenobu, Y Yamada, T Noda, Y Ito, M Satake, ... Cell 102 (2), 199-209, 2000 | 665 | 2000 |
| IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release. N Kurihara, D Bertolini, T Suda, Y Akiyama, GD Roodman Journal of Immunology (Baltimore, Md.: 1950) 144 (11), 4226-4230, 1990 | 642 | 1990 |
| v-ATPase V0 subunit d2–deficient mice exhibit impaired osteoclast fusion and increased bone formation SH Lee, J Rho, D Jeong, JY Sul, T Kim, N Kim, JS Kang, T Miyamoto, ... Nature medicine 12 (12), 1403-1409, 2006 | 592 | 2006 |
| Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon–dependent exhaustion T Sato, N Onai, H Yoshihara, F Arai, T Suda, T Ohteki Nature medicine 15 (6), 696-700, 2009 | 482 | 2009 |
Keiyo TakuboTohoku University Graduate School of Medicine/National Center for Global Health and MedicineVerified email at ri.ncgm.go.jp
