| Crosslinking and composition influence the surface properties, mechanical stiffness and cell reactivity of collagen-based films CN Grover, JH Gwynne, N Pugh, S Hamaia, RW Farndale, SM Best, ... Acta biomaterialia 8 (8), 3080-3090, 2012 | 248 | 2012 |
| OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice AD Barrow, N Raynal, TL Andersen, DA Slatter, D Bihan, N Pugh, M Cella, ... The Journal of clinical investigation 121 (9), 2011 | 247 | 2011 |
| Identification of platelet function defects by multi-parameter assessment of thrombus formation SM De Witt, F Swieringa, R Cavill, MME Lamers, R Van Kruchten, ... Nature communications 5 (1), 4257, 2014 | 246 | 2014 |
| Cell–collagen interactions: the use of peptide Toolkits to investigate collagen–receptor interactions RW Farndale, T Lisman, D Bihan, S Hamaia, CS Smerling, N Pugh, ... Biochemical Society Transactions 36 (2), 241-250, 2008 | 215 | 2008 |
| Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood N Pugh, AMC Simpson, PA Smethurst, PG de Groot, N Raynal, ... Blood, The Journal of the American Society of Hematology 115 (24), 5069-5079, 2010 | 141 | 2010 |
| Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood SM Jung, M Moroi, K Soejima, T Nakagaki, Y Miura, MC Berndt, ... Journal of Biological Chemistry 287 (35), 30000-30013, 2012 | 128 | 2012 |
| Thrombospondin-1 promotes matrix homeostasis by interacting with collagen and lysyl oxidase precursors and collagen cross-linking sites S Rosini, N Pugh, AM Bonna, DJS Hulmes, RW Farndale, JC Adams Science signaling 11 (532), eaar2566, 2018 | 94 | 2018 |
| Mapping of potent and specific binding motifs, GLOGEN and GVOGEA, for integrin α1β1 using collagen toolkits II and III SW Hamaia, N Pugh, N Raynal, B Némoz, R Stone, D Gullberg, D Bihan, ... Journal of Biological Chemistry 287 (31), 26019-26028, 2012 | 73 | 2012 |
| Putative GTPase GIMAP1 is critical for the development of mature B and T lymphocytes A Saunders, LMC Webb, ML Janas, A Hutchings, J Pascall, C Carter, ... Blood, The Journal of the American Society of Hematology 115 (16), 3249-3257, 2010 | 67 | 2010 |
| The contribution of zinc to platelet behaviour during haemostasis and thrombosis KA Taylor, N Pugh Metallomics 8 (2), 144-155, 2016 | 58 | 2016 |
| Expression of the Ian family of putative GTPases during T cell development and description of an Ian with three sets of GTP/GDP-binding motifs C Dion, C Carter, L Hepburn, WJ Coadwell, G Morgan, M Graham, ... International immunology 17 (9), 1257-1268, 2005 | 47 | 2005 |
| First analysis of a bacterial collagen-binding protein with collagen Toolkits: promiscuous binding of YadA to collagens may explain how YadA interferes with host processes JC Leo, H Elovaara, D Bihan, N Pugh, SK Kilpinen, N Raynal, M Skurnik, ... Infection and immunity 78 (7), 3226-3236, 2010 | 45 | 2010 |
| Zinc is a transmembrane agonist that induces platelet activation in a tyrosine phosphorylation-dependent manner BR Watson, NA White, KA Taylor, JM Howes, JDM Malcor, D Bihan, ... Metallomics 8 (1), 91-100, 2016 | 44 | 2016 |
| Stapled peptides as a new technology to investigate protein–protein interactions in human platelets J Iegre, NS Ahmed, JS Gaynord, Y Wu, KM Herlihy, YS Tan, ... Chemical Science 9 (20), 4638-4643, 2018 | 43 | 2018 |
| A role for adhesion and degranulation‐promoting adapter protein in collagen‐induced platelet activation mediated via integrin α2β1 GE Jarvis, D Bihan, S Hamaia, N Pugh, CJG Ghevaert, AC Pearce, ... Journal of Thrombosis and Haemostasis 10 (2), 268-277, 2012 | 39 | 2012 |
| Monitoring the intracellular store Ca2+ concentration in agonist‐stimulated, intact human platelets by using Fluo‐5N SO Sage, N Pugh, MJ Mason, AGS Harper Journal of Thrombosis and Haemostasis 9 (3), 540-551, 2011 | 31 | 2011 |
| Zinc regulates reactive oxygen species generation in platelets ME Lopes-Pires, NS Ahmed, D Vara, JM Gibbins, G Pula, N Pugh Platelets 32 (3), 368-377, 2021 | 27 | 2021 |
| Differential integrin activity mediated by platelet collagen receptor engagement under flow conditions N Pugh, BD Maddox, D Bihan, KA Taylor, MP Mahaut-Smith, ... Thrombosis and haemostasis 117 (08), 1588-1600, 2017 | 26 | 2017 |
| Pericellular Ca2+ recycling potentiates thrombin‐evoked Ca2+ signals in human platelets SO Sage, N Pugh, RW Farndale, AGS Harper Physiological reports 1 (5), 2013 | 23 | 2013 |
| Dynamic analysis of platelet deposition to resolve platelet adhesion receptor activity in whole blood at arterial shear rate N Pugh, D Bihan, DJ Perry, RW Farndale Platelets 26 (3), 216-219, 2015 | 20 | 2015 |
