| Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice Nature neuroscience 20 (5), 648-660, 2017 | 185 | 2017 |
| Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTR up-regulation and astrocyte-mediated … A Miguez, G Garcia-Diaz Barriga, V Brito, M Straccia, A Giralt, S Ginés, ... Human molecular genetics 24 (17), 4958-4970, 2015 | 132 | 2015 |
| 7, 8-dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington’s disease mouse model through specific activation of the PLCγ1 pathway G García-Díaz Barriga, A Giralt, M Anglada-Huguet, N Gaja-Capdevila, ... Human molecular genetics 26 (16), 3144-3160, 2017 | 62 | 2017 |
| Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis JC Fraire, G Houthaeve, J Liu, L Raes, L Vermeulen, S Stremersch, ... Journal of controlled release 319, 262-275, 2020 | 55 | 2020 |
| RNA-Seq transcriptomic profiling of primary murine microglia treated with LPS or LPS+ IFNγ M Pulido-Salgado, JM Vidal-Taboada, GGD Barriga, C Solà, J Saura Scientific Reports 8 (1), 16096, 2018 | 51 | 2018 |
| Increased translation as a novel pathogenic mechanism in Huntington’s disease J Creus-Muncunill, R Badillos-Rodríguez, M Garcia-Forn, M Masana, ... Brain 142 (10), 3158-3175, 2019 | 47 | 2019 |
| Prostaglandin E2 EP2 activation reduces memory decline in R6/1 mouse model of Huntington's disease by the induction of BDNF-dependent synaptic plasticity M Anglada-Huguet, L Vidal-Sancho, A Giralt, GGD Barriga, X Xifro, ... Neurobiology of Disease 95, 22-34, 2016 | 36 | 2016 |
| M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington’s disease S Fernández-García, S Conde-Berriozabal, E García-García, ... Elife 9, e57017, 2020 | 35 | 2020 |
| NETCAL: an interactive platform for large-scale, NETwork and population dynamics analysis of CALcium imaging recordings JG Orlandi, S Fernández-García, A Comella-Bolla, M Masana, ... Neuroscience, 2017 | 26 | 2017 |
| Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis M Pulido-Salgado, JM Vidal-Taboada, G Garcia Diaz-Barriga, J Serratosa, ... Journal of neuroinflammation 14, 1-20, 2017 | 21 | 2017 |
| Systematic quantification of synapses in primary neuronal culture P Verstraelen, GGD Barriga, M Verschuuren, B Asselbergh, R Nuydens, ... Iscience 23 (9), 2020 | 20 | 2020 |
| Early Downregulation of p75NTR by Genetic and Pharmacological Approaches Delays the Onset of Motor Deficits and Striatal Dysfunction in Huntington’s Disease … N Suelves, A Miguez, S López-Benito, GGD Barriga, A Giralt, ... Molecular Neurobiology 56, 935-953, 2019 | 20 | 2019 |
| Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell–derived medium spiny neurons M Straccia, GGD Barriga, P Sanders, G Bombau, J Carrere, PB Mairal, ... Molecular Therapy Methods & Clinical Development 2, 2015 | 20 | 2015 |
| Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons R Martín-Ibáñez, M Pardo, A Giralt, A Miguez, I Guardia, L Marion-Poll, ... Development 144 (8), 1566-1577, 2017 | 18 | 2017 |
| Deficits in coordinated neuronal activity and network topology are striatal hallmarks in Huntington’s disease S Fernández-García, JG Orlandi, GA García-Díaz Barriga, MJ Rodríguez, ... BMC biology 18, 1-16, 2020 | 16 | 2020 |
| A FBN1 3′ UTR mutation variant is associated with endoplasmic reticulum stress in aortic aneurysm in Marfan syndrome AM Siegert, GG Díaz-Barriga, A Esteve-Codina, M Navas-Madroñal, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (1), 107-114, 2019 | 16 | 2019 |
| High-throughput microscopy exposes a pharmacological window in which dual leucine zipper kinase inhibition preserves neuronal network connectivity M Verschuuren, P Verstraelen, G García-Díaz Barriga, I Cilissen, ... Acta neuropathologica communications 7, 1-16, 2019 | 15 | 2019 |
| Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons V Telezhkin, M Straccia, P Yarova, M Pardo, S Yung, NN Vinh, ... Pflügers Archiv-European Journal of Physiology 470, 1359-1376, 2018 | 14 | 2018 |
| Pharmacogenetic modulation of STEP improves motor and cognitive function in a mouse model of Huntington's disease M García-Forn, S Martínez-Torres, GGD Barriga, J Alberch, M Milà, ... Neurobiology of Disease 120, 88-97, 2018 | 12 | 2018 |
| Huntington’s disease: novel therapeutic perspectives hanging in the balance A Saavedra, G Garcia-Diaz Barriga, E Pérez-Navarro, J Alberch Expert opinion on therapeutic targets 22 (5), 385-399, 2018 | 11 | 2018 |
Jordi AlberchFull Professor, Medical School, Institute of Neurosciences, University of BarcelonaBestätigte E-Mail-Adresse bei ub.edu
