High-Affinity, Non-Nucleotide-Derived Competitive Antagonists of Platelet P2Y12 Receptors Y Baqi, K Atzler, M Köse, M Glänzel, CE Müller Journal of medicinal chemistry 52 (12), 3784-3793, 2009 | 113 | 2009 |
Annexin A6—Linking Ca2+ signaling with cholesterol transport C Enrich, C Rentero, SV de Muga, M Reverter, V Mulay, P Wood, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (5), 935-947, 2011 | 112 | 2011 |
Diindolylmethane derivatives: potent agonists of the immunostimulatory orphan G protein-coupled receptor GPR84 T Pillaiyar, M Köse, K Sylvester, H Weighardt, D Thimm, G Borges, ... Journal of medicinal chemistry 60 (9), 3636-3655, 2017 | 92 | 2017 |
Annexin A6-regulator of the EGFR/Ras signalling pathway and cholesterol homeostasis T Grewal, M Koese, C Rentero, C Enrich The international journal of biochemistry & cell biology 42 (5), 580-584, 2010 | 88 | 2010 |
Annexin A6 is a scaffold for PKCα to promote EGFR inactivation M Koese, C Rentero, BP Kota, M Hoque, R Cairns, P Wood, ... Oncogene 32 (23), 2858-2872, 2013 | 86 | 2013 |
Differential regulation of RasGAPs in cancer T Grewal, M Koese, F Tebar, C Enrich Genes & cancer 2 (3), 288-297, 2011 | 71 | 2011 |
GPCRs and EGFR–Cross-talk of membrane receptors in cancer M Köse Bioorganic & Medicinal Chemistry Letters 27 (16), 3611-3620, 2017 | 66 | 2017 |
Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies A Abdelrahman, V Namasivayam, S Hinz, AC Schiedel, M Köse, M Burton, ... Biochemical pharmacology 125, 41-54, 2017 | 61 | 2017 |
Annexin A6 and late endosomal cholesterol modulate integrin recycling and cell migration A García-Melero, M Reverter, M Hoque, E Meneses-Salas, M Koese, ... Journal of Biological Chemistry 291 (3), 1320-1335, 2016 | 58 | 2016 |
Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling M Poeter, S Radke, M Koese, F Hessner, A Hegemann, A Musiol, V Gerke, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (7), 1700-1711, 2013 | 48 | 2013 |
Synthesis and biological activity of tricyclic cycloalkylimidazo-, pyrimido-and diazepinopurinediones A Drabczyńska, O Yuzlenko, M Köse, M Paskaleva, AC Schiedel, ... European journal of medicinal chemistry 46 (9), 3590-3607, 2011 | 43 | 2011 |
6-(Ar) Alkylamino-substituted uracil derivatives: lipid mimetics with potent activity at the orphan G Protein-Coupled Receptor 84 (GPR84) T Pillaiyar, M Köse, V Namasivayam, K Sylvester, G Borges, D Thimm, ... ACS omega 3 (3), 3365-3383, 2018 | 35 | 2018 |
1, 3-Dialkyl-substituted tetrahydropyrimido [1, 2-f] purine-2, 4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases P Koch, R Akkari, A Brunschweiger, T Borrmann, M Schlenk, P Küppers, ... Bioorganic & medicinal chemistry 21 (23), 7435-7452, 2013 | 34 | 2013 |
Fluorescent-Labeled Selective Adenosine A2B Receptor Antagonist Enables Competition Binding Assay by Flow Cytometry M Kose, S Gollos, T Karcz, A Fiene, F Heisig, A Behrenswerth, ... Journal of Medicinal Chemistry 61 (10), 4301-4316, 2018 | 33 | 2018 |
2‐Amino[1,2,4]triazolo[1,5‐c]quinazolines and Derived Novel Heterocycles: Syntheses and Structure–Activity Relationships of Potent Adenosine Receptor … JC Burbiel, W Ghattas, P Küppers, M Köse, S Lacher, AM Herzner, ... ChemMedChem 11 (20), 2272-2286, 2016 | 33 | 2016 |
Cyclopropane-Containing Fatty Acids from the Marine Bacterium Labrenzia sp. 011 with Antimicrobial and GPR84 Activity J Amiri Moghaddam, A Dávila-Céspedes, S Kehraus, M Crüsemann, ... Marine drugs 16 (10), 369, 2018 | 31 | 2018 |
8‐Benzyltetrahydropyrazino[2,1‐f]purinediones: Water‐Soluble Tricyclic Xanthine Derivatives as Multitarget Drugs for Neurodegenerative Diseases A Brunschweiger, P Koch, M Schlenk, F Pineda, P Küppers, S Hinz, ... ChemMedChem 9 (8), 1704-1724, 2014 | 31 | 2014 |
Nucleoside/nucleobase transporters: drug targets of the future? M Köse, AC Schiedel Future medicinal chemistry 1 (2), 303-326, 2009 | 30 | 2009 |
An agonist radioligand for the proinflammatory lipid-activated G protein-coupled receptor GPR84 providing structural insights M Köse, T Pillaiyar, V Namasivayam, E De Filippo, K Sylvester, T Ulven, ... Journal of medicinal chemistry 63 (5), 2391-2410, 2019 | 23 | 2019 |
Development of [3H]2-Carboxy-4,6-dichloro-1H-indole-3-propionic Acid ([3H]PSB-12150): A Useful Tool for Studying GPR17 M Köse, K Ritter, K Thiemke, M Gillard, E Kostenis, CE Müller ACS medicinal chemistry letters 5 (4), 326-330, 2014 | 23 | 2014 |