Isolation and characterization of human β-defensin-3, a novel human inducible peptide antibiotic J Harder, J Bartels, E Christophers, JM Schröder Journal of Biological Chemistry 276 (8), 5707-5713, 2001 | 1937 | 2001 |
A peptide antibiotic from human skin J Harder, J Bartels, E Christophers, JM Schröder Nature 387 (6636), 861-861, 1997 | 1935 | 1997 |
NOD2 (CARD15) mutations in Crohn’s disease are associated with diminished mucosal α-defensin expression J Wehkamp, J Harder, M Weichenthal, M Schwab, E Schäffeler, M Schlee, ... Gut 53 (11), 1658-1664, 2004 | 1124 | 2004 |
Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection R Gläser, J Harder, H Lange, J Bartels, E Christophers, JM Schröder Nature immunology 6 (1), 57-64, 2005 | 791 | 2005 |
NF-κB-and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium J Wehkamp, J Harder, K Wehkamp, B Wehkamp-von Meissner, M Schlee, ... Infection and immunity 72 (10), 5750-5758, 2004 | 672 | 2004 |
Human beta-defensin-2 JM Schröder, J Harder The international journal of biochemistry & cell biology 31 (6), 645-651, 1999 | 667 | 1999 |
Mucoid Pseudomonas aeruginosa, TNF-α, and IL-1 β, but Not IL-6, Induce Human β-Defensin-2 in Respiratory Epithelia J Harder, U Meyer-Hoffert, LM Teran, L Schwichtenberg, J Bartels, ... American Journal of Respiratory Cell and Molecular Biology 22 (6), 714-721, 2000 | 637 | 2000 |
RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin J Harder, JM Schröder Journal of Biological Chemistry 277 (48), 46779-46784, 2002 | 551 | 2002 |
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions Y Dombrowski, M Peric, S Koglin, C Kammerbauer, C Göß, D Anz, ... Science translational medicine 3 (82), 82ra38-82ra38, 2011 | 470 | 2011 |
Probiotic lactobacilli and VSL# 3 induce enterocyte β‐defensin 2 M Schlee, J Harder, B Köten, EF Stange, J Wehkamp, K Fellermann Clinical & Experimental Immunology 151 (3), 528-535, 2008 | 467 | 2008 |
Inducible and constitutive β‐defensins are differentially expressed in Crohn's disease and ulcerative colitis J Wehkamp, J Harder, M Weichenthal, O Mueller, KR Herrlinger, ... Inflammatory bowel diseases 9 (4), 215-223, 2003 | 461 | 2003 |
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2 E Voss, J Wehkamp, K Wehkamp, EF Stange, JM Schröder, J Harder Journal of Biological Chemistry 281 (4), 2005-2011, 2006 | 424 | 2006 |
Antimicrobial skin peptides and proteins JM Schröder, J Harder Cellular and Molecular Life Sciences CMLS 63 (4), 469-486, 2006 | 359 | 2006 |
Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins J Harder, JM Schröder Journal of leukocyte biology 77 (4), 476-486, 2005 | 314 | 2005 |
Differential gene induction of human β-defensins (hBD-1,-2,-3, and-4) in keratinocytes is inhibited by retinoic acid J Harder, U Meyer-Hoffert, K Wehkamp, L Schwichtenberg, JM Schröder Journal of Investigative Dermatology 123 (3), 522-529, 2004 | 302 | 2004 |
Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury J Harder, S Dressel, M Wittersheim, J Cordes, U Meyer-Hoffert, ... Journal of Investigative Dermatology 130 (5), 1355-1364, 2010 | 301 | 2010 |
Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1α released from dying cells T Eigenbrod, JH Park, J Harder, Y Iwakura, G Núñez The Journal of Immunology 181 (12), 8194-8198, 2008 | 299 | 2008 |
Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-κB activation but proceeds independently of TLR signaling and P2X7 receptor J Harder, L Franchi, R Muñoz-Planillo, JH Park, T Reimer, G Núñez The Journal of Immunology 183 (9), 5823-5829, 2009 | 291 | 2009 |
Antitumor activity of the antimicrobial peptide magainin II against bladder cancer cell lines J Lehmann, M Retz, SS Sidhu, H Suttmann, M Sell, F Paulsen, J Harder, ... European urology 50 (1), 141-147, 2006 | 271 | 2006 |
Uncovering the evolutionary history of innate immunity: The simple metazoan Hydra uses epithelial cells for host defence TCG Bosch, R Augustin, F Anton-Erxleben, S Fraune, G Hemmrich, H Zill, ... Developmental & Comparative Immunology 33 (4), 559-569, 2009 | 264 | 2009 |