Cystobactamids: myxobacterial topoisomerase inhibitors exhibiting potent antibacterial activity S Baumann, J Herrmann, R Raju, H Steinmetz, KI Mohr, S Hüttel, ... Angewandte Chemie International Edition 53 (52), 14605-14609, 2014 | 121 | 2014 |
Improving natural products identification through targeted LC-MS/MS in an untargeted secondary metabolomics workflow T Hoffmann, D Krug, S Hüttel, R Müller Analytical chemistry 86 (21), 10780-10788, 2014 | 74 | 2014 |
Aetheramides A and B, Potent HIV-Inhibitory Depsipeptides from a Myxobacterium of the New Genus “Aetherobacter” A Plaza, R Garcia, G Bifulco, JP Martinez, S Hüttel, F Sasse, ... Organic letters 14 (11), 2854-2857, 2012 | 58 | 2012 |
Self-resistance and cell wall composition in the glycopeptide producer Amycolatopsis balhimycina TF Schäberle, W Vollmer, HJ Frasch, S Hüttel, A Kulik, M Röttgen, ... Antimicrobial agents and chemotherapy 55 (9), 4283-4289, 2011 | 43 | 2011 |
Targeting the actin cytoskeleton: selective antitumor action via trapping PKC ɛ F Foerster, S Braig, C Moser, R Kubisch, J Busse, E Wagner, ... Cell death & disease 5 (8), e1398-e1398, 2014 | 39 | 2014 |
Discovery and Total Synthesis of Natural Cystobactamid Derivatives with Superior Activity against Gram‐Negative Pathogens S Hüttel, G Testolin, J Herrmann, T Planke, F Gille, M Moreno, M Stadler, ... Angewandte Chemie International Edition 56 (41), 12760-12764, 2017 | 36* | 2017 |
Biological and chemical diversity go hand in hand: Basidiomycota as source of new pharmaceuticals and agrochemicals B Sandargo, C Chepkirui, T Cheng, L Chaverra-Muñoz, B Thongbai, ... Biotechnology advances 37 (6), 107344, 2019 | 31 | 2019 |
Biosynthesis and heterologous production of vioprolides: Rational biosynthetic engineering and unprecedented 4‐methylazetidinecarboxylic acid formation F Yan, D Auerbach, Y Chai, L Keller, Q Tu, S Hüttel, A Glemser, HA Grab, ... Angewandte Chemie International Edition 57 (28), 8754-8759, 2018 | 30 | 2018 |
Discovery and Biological Activity of New Chondramides from Chondromyces sp. J Herrmann, S Hüttel, R Müller ChemBioChem 14 (13), 1573-1580, 2013 | 26 | 2013 |
Strategies for the discovery and development of new antibiotics from natural products: three case studies J Herrmann, T Lukežič, A Kling, S Baumann, S Hüttel, H Petković, ... How to Overcome the Antibiotic Crisis, 339-363, 2016 | 17 | 2016 |
Cystobactamide: Topoisomerase‐Inhibitoren aus Myxobakterien mit hoher antibakterieller Aktivität S Baumann, J Herrmann, R Raju, H Steinmetz, KI Mohr, S Hüttel, ... Angewandte Chemie 126 (52), 14835-14839, 2014 | 16 | 2014 |
Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy C Pergola, K Schubert, S Pace, J Ziereisen, F Nikels, O Scherer, S Hüttel, ... Scientific reports 7 (1), 1-12, 2017 | 14 | 2017 |
Biosynthesis of the Klebsiella oxytoca Pathogenicity Factor Tilivalline: Heterologous Expression, in Vitro Biosynthesis, and Inhibitor Development A von Tesmar, M Hoffmann, A Abou Fayad, S Hüttel, V Schmitt, ... ACS chemical biology 13 (3), 812-819, 2018 | 12 | 2018 |
Methods to optimize myxobacterial fermentations using off-gas analysis S Hüttel, R Müller Microbial cell factories 11 (1), 1-11, 2012 | 9 | 2012 |
Cystobactamids 920-1 and 920-2: Assignment of the Constitution and Relative Configuration by Total Synthesis T Planke, M Moreno, S Hüttel, J Fohrer, F Gille, MD Norris, M Siebke, ... Organic letters 21 (5), 1359-1363, 2019 | 7 | 2019 |
Furanones and anthranilic acid derivatives from the endophytic fungus Dendrothyrium variisporum RB Teponno, SR Noumeur, SE Helaly, S Hüttel, D Harzallah, M Stadler Molecules 22 (10), 1674, 2017 | 7 | 2017 |
Biosynthese und heterologe Expression der Vioprolide: rationale gentechnische Eingriffe in die Biosynthese und 4‐Methylazetidincarbonsäure‐Bildung F Yan, D Auerbach, Y Chai, L Keller, Q Tu, S Hüttel, A Glemser, HA Grab, ... Angewandte Chemie 130 (28), 8890-8895, 2018 | 6 | 2018 |
Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry S Blockus, SM Sake, M Wetzke, C Grethe, T Graalmann, M Pils, ... Antiviral research 177, 104774, 2020 | 4 | 2020 |
Semisynthesis and biological evaluation of amidochelocardin derivatives as broad-spectrum antibiotics C Grandclaudon, NVS Birudukota, WAM Elgaher, RP Jumde, S Yahiaoui, ... European journal of medicinal chemistry 188, 112005, 2020 | 3 | 2020 |
Large scale production and downstream processing of labyrinthopeptins from the actinobacterium Actinomadura namibiensis Z Rupcic, S Hüttel, S Bernecker, S Kanaki, M Stadler Bioengineering 5 (2), 42, 2018 | 3 | 2018 |