Stephan Hüttel
Stephan Hüttel
Head of Fermentation Department, Helmholtz Centre for Infection Research
Bestätigte E-Mail-Adresse bei helmholtz-hzi.de
TitelZitiert vonJahr
Cystobactamids: myxobacterial topoisomerase inhibitors exhibiting potent antibacterial activity
S Baumann, J Herrmann, R Raju, H Steinmetz, KI Mohr, S Hüttel, ...
Angewandte Chemie International Edition 53 (52), 14605-14609, 2014
942014
Improving natural products identification through targeted LC-MS/MS in an untargeted secondary metabolomics workflow
T Hoffmann, D Krug, S Hüttel, R Müller
Analytical chemistry 86 (21), 10780-10788, 2014
662014
Aetheramides A and B, Potent HIV-Inhibitory Depsipeptides from a Myxobacterium of the New Genus “Aetherobacter
A Plaza, R Garcia, G Bifulco, JP Martinez, S Hüttel, F Sasse, ...
Organic letters 14 (11), 2854-2857, 2012
552012
Self-resistance and cell wall composition in the glycopeptide producer Amycolatopsis balhimycina
TF Schäberle, W Vollmer, HJ Frasch, S Hüttel, A Kulik, M Röttgen, ...
Antimicrobial agents and chemotherapy 55 (9), 4283-4289, 2011
372011
Targeting the actin cytoskeleton: selective antitumor action via trapping PKCɛ
F Foerster, S Braig, C Moser, R Kubisch, J Busse, E Wagner, ...
Cell death & disease 5 (8), e1398, 2014
282014
Discovery and Biological Activity of New Chondramides from Chondromyces sp.
J Herrmann, S Hüttel, R Müller
Chembiochem 14 (13), 1573-1580, 2013
222013
Discovery and Total Synthesis of Natural Cystobactamid Derivatives with Superior Activity against Gram‐Negative Pathogens
S Hüttel, G Testolin, J Herrmann, T Planke, F Gille, M Moreno, M Stadler, ...
Angewandte Chemie International Edition 56 (41), 12760-12764, 2017
19*2017
Biosynthesis and Heterologous Production of Vioprolides: Rational Biosynthetic Engineering and Unprecedented 4‐Methylazetidinecarboxylic Acid Formation
F Yan, D Auerbach, Y Chai, L Keller, Q Tu, S Hüttel, A Glemser, HA Grab, ...
Angewandte Chemie International Edition 57 (28), 8754-8759, 2018
152018
Cystobactamide: Topoisomerase‐Inhibitoren aus Myxobakterien mit hoher antibakterieller Aktivität
S Baumann, J Herrmann, R Raju, H Steinmetz, KI Mohr, S Hüttel, ...
Angewandte Chemie 126 (52), 14835-14839, 2014
112014
Strategies for the discovery and development of new antibiotics from natural products: three case studies
J Herrmann, T Lukežič, A Kling, S Baumann, S Hüttel, H Petković, ...
How to Overcome the Antibiotic Crisis, 339-363, 2016
102016
Biological and chemical diversity go hand in hand: Basidomycota as source of new pharmaceuticals and agrochemicals
B Sandargo, C Chepkirui, T Cheng, L Chaverra-Munoz, B Thongbai, ...
Biotechnology advances, 2019
92019
Methods to optimize myxobacterial fermentations using off-gas analysis
S Hüttel, R Müller
Microbial cell factories 11 (1), 59, 2012
82012
Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy
C Pergola, K Schubert, S Pace, J Ziereisen, F Nikels, O Scherer, S Hüttel, ...
Scientific reports 7, 41434, 2017
72017
Biosynthesis of the Klebsiella oxytoca Pathogenicity Factor Tilivalline: Heterologous Expression, in Vitro Biosynthesis, and Inhibitor Development
A von Tesmar, M Hoffmann, A Abou Fayad, S Hüttel, V Schmitt, ...
ACS Chemical Biology 13 (3), 812-819, 2018
52018
Furanones and anthranilic acid derivatives from the endophytic fungus Dendrothyrium variisporum
R Teponno, S Noumeur, S Helaly, S Hüttel, D Harzallah, M Stadler
Molecules 22 (10), 1674, 2017
52017
Optimization of the biotechnological production of a novel class of anti-MRSA antibiotics from Chitinophaga sancti
A Beckmann, S Hüttel, V Schmitt, R Müller, M Stadler
Microbial cell factories 16 (1), 143, 2017
22017
Cystobactamids 920-1 and 920-2: Assignment of the Constitution and Relative Configuration by Total Synthesis
T Planke, M Moreno, S Hüttel, J Fohrer, F Gille, MD Norris, M Siebke, ...
Organic letters 21 (5), 1359-1363, 2019
12019
Biosynthese und heterologe Expression der Vioprolide: rationale gentechnische Eingriffe in die Biosynthese und 4‐Methylazetidincarbonsäure‐Bildung
F Yan, D Auerbach, Y Chai, L Keller, Q Tu, S Hüttel, A Glemser, HA Grab, ...
Angewandte Chemie 130 (28), 8890-8895, 2018
12018
Large Scale Production and Downstream Processing of Labyrinthopeptins from the Actinobacterium Actinomadura namibiensis
Z Rupcic, S Hüttel, S Bernecker, S Kanaki, M Stadler
Bioengineering 5 (2), 42, 2018
12018
Schätze aus dem Boden: innovative Prozesse zur Wirkstofffindung
S Hüttel, J Herrmann, R Müller
BIOspektrum 19 (5), 520-522, 2013
12013
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