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Stephan Hüttel
Stephan Hüttel
Head of Fermentation Department, Helmholtz Centre for Infection Research
Bestätigte E-Mail-Adresse bei helmholtz-hzi.de
Titel
Zitiert von
Zitiert von
Jahr
Cystobactamids: myxobacterial topoisomerase inhibitors exhibiting potent antibacterial activity
S Baumann, J Herrmann, R Raju, H Steinmetz, KI Mohr, S Hüttel, ...
Angewandte Chemie International Edition 53 (52), 14605-14609, 2014
1622014
Improving natural products identification through targeted LC-MS/MS in an untargeted secondary metabolomics workflow
T Hoffmann, D Krug, S Hüttel, R Müller
Analytical chemistry 86 (21), 10780-10788, 2014
882014
Biological and chemical diversity go hand in hand: Basidiomycota as source of new pharmaceuticals and agrochemicals
B Sandargo, C Chepkirui, T Cheng, L Chaverra-Muñoz, B Thongbai, ...
Biotechnology advances 37 (6), 107344, 2019
642019
Aetheramides A and B, Potent HIV-Inhibitory Depsipeptides from a Myxobacterium of the New Genus “Aetherobacter
A Plaza, R Garcia, G Bifulco, JP Martinez, S Hüttel, F Sasse, ...
Organic letters 14 (11), 2854-2857, 2012
632012
Discovery and Total Synthesis of Natural Cystobactamid Derivatives with Superior Activity against Gram‐Negative Pathogens
S Hüttel, G Testolin, J Herrmann, T Planke, F Gille, M Moreno, M Stadler, ...
Angewandte Chemie International Edition 56 (41), 12760-12764, 2017
55*2017
Targeting the actin cytoskeleton: selective antitumor action via trapping PKCɛ
F Foerster, S Braig, C Moser, R Kubisch, J Busse, E Wagner, ...
Cell death & disease 5 (8), e1398-e1398, 2014
502014
Self-resistance and cell wall composition in the glycopeptide producer Amycolatopsis balhimycina
TF Schäberle, W Vollmer, HJ Frasch, S Hüttel, A Kulik, M Röttgen, ...
Antimicrobial agents and chemotherapy 55 (9), 4283-4289, 2011
452011
Biosynthesis and heterologous production of vioprolides: Rational biosynthetic engineering and unprecedented 4‐methylazetidinecarboxylic acid formation
F Yan, D Auerbach, Y Chai, L Keller, Q Tu, S Hüttel, A Glemser, HA Grab, ...
Angewandte Chemie International Edition 57 (28), 8754-8759, 2018
412018
Discovery and Biological Activity of New Chondramides from Chondromyces sp.
J Herrmann, S Hüttel, R Müller
Chembiochem 14 (13), 1573-1580, 2013
322013
Strategies for the discovery and development of new antibiotics from natural products: three case studies
J Herrmann, T Lukežič, A Kling, S Baumann, S Hüttel, H Petković, ...
How to Overcome the Antibiotic Crisis, 339-363, 2016
242016
Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy
C Pergola, K Schubert, S Pace, J Ziereisen, F Nikels, O Scherer, S Hüttel, ...
Scientific reports 7 (1), 1-12, 2017
212017
Cystobactamide: Topoisomerase‐Inhibitoren aus Myxobakterien mit hoher antibakterieller Aktivität
S Baumann, J Herrmann, R Raju, H Steinmetz, KI Mohr, S Hüttel, ...
Angewandte Chemie 126 (52), 14835-14839, 2014
212014
Biosynthesis of the Klebsiella oxytoca Pathogenicity Factor Tilivalline: Heterologous Expression, in Vitro Biosynthesis, and Inhibitor Development
A von Tesmar, M Hoffmann, A Abou Fayad, S Hüttel, V Schmitt, ...
ACS chemical biology 13 (3), 812-819, 2018
202018
Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry
S Blockus, SM Sake, M Wetzke, C Grethe, T Graalmann, M Pils, ...
Antiviral research 177, 104774, 2020
182020
Cystobactamids 920-1 and 920-2: Assignment of the Constitution and Relative Configuration by Total Synthesis
T Planke, M Moreno, S Hüttel, J Fohrer, F Gille, MD Norris, M Siebke, ...
Organic letters 21 (5), 1359-1363, 2019
132019
Furanones and anthranilic acid derivatives from the endophytic fungus Dendrothyrium variisporum
RB Teponno, SR Noumeur, SE Helaly, S Hüttel, D Harzallah, M Stadler
Molecules 22 (10), 1674, 2017
122017
Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections
A Schiefer, MP Hübner, A Krome, C Lämmer, A Ehrens, T Aden, ...
PLoS neglected tropical diseases 14 (12), e0008930, 2020
102020
Methods to optimize myxobacterial fermentations using off-gas analysis
S Hüttel, R Müller
Microbial Cell Factories 11 (1), 1-11, 2012
92012
Cystobactamides
S Baumann, J Herrmann, M Kathrin, H Steinmetz, K Gerth, R Ritesh, ...
82021
The nuclear export inhibitor aminoratjadone is a potent effector in extracellular-targeted drug conjugates
P Klahn, V Fetz, A Ritter, W Collisi, B Hinkelmann, T Arnold, W Tegge, ...
Chemical science 10 (20), 5197-5210, 2019
82019
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