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Degiacomi Giulia
Degiacomi Giulia
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Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis
J Neres, F Pojer, E Molteni, LR Chiarelli, N Dhar, S Boy-Röttger, S Buroni, ...
Science translational medicine 4 (150), 150ra121-150ra121, 2012
2032012
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals Are Uniformly Susceptible to Benzothiazinones
MR Pasca, G Degiacomi, ALJL Ribeiro, F Zara, P De Mori, B Heym, ...
Antimicrobial agents and chemotherapy 54 (4), 1616-1618, 2010
1312010
Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients
G Degiacomi, JC Sammartino, LR Chiarelli, O Riabova, V Makarov, ...
International journal of molecular sciences 20 (23), 5868, 2019
1142019
Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression
G Degiacomi, A Benjak, J Madacki, F Boldrin, R Provvedi, G Palù, ...
Scientific reports 7 (1), 43495, 2017
1142017
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance
G Manina, M Bellinzoni, MR Pasca, J Neres, A Milano, ...
Molecular microbiology 77 (5), 1172-1185, 2010
932010
PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis
B Rieck, G Degiacomi, M Zimmermann, A Cascioferro, F Boldrin, ...
PLoS pathogens 13 (5), e1006399, 2017
892017
Thiophenecarboxamide derivatives activated by EthA kill Mycobacterium tuberculosis by inhibiting the CTP synthetase PyrG
G Mori, LR Chiarelli, M Esposito, V Makarov, M Bellinzoni, RC Hartkoorn, ...
Chemistry & biology 22 (7), 917-927, 2015
742015
GarA is an essential regulator of metabolism in Mycobacterium tuberculosis
M Ventura, B Rieck, F Boldrin, G Degiacomi, M Bellinzoni, N Barilone, ...
Molecular microbiology 90 (2), 356-366, 2013
662013
Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis
AL de Jesus Lopes Ribeiro, G Degiacomi, F Ewann, S Buroni, ...
PloS one 6 (11), e26675, 2011
642011
In vitro study of bedaquiline resistance in Mycobacterium tuberculosis multi-drug resistant clinical isolates
G Degiacomi, JC Sammartino, V Sinigiani, P Marra, A Urbani, MR Pasca
Frontiers in microbiology 11, 559469, 2020
572020
The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo
F Boldrin, M Ventura, G Degiacomi, S Ravishankar, C Sala, Z Svetlikova, ...
Journal of bacteriology 196 (19), 3441-3451, 2014
482014
Promiscuous targets for antitubercular drug discovery: The paradigm of DprE1 and MmpL3
G Degiacomi, JM Belardinelli, MR Pasca, E De Rossi, G Riccardi, ...
Applied Sciences 10 (2), 623, 2020
472020
Whole cell screen based identification of spiropiperidines with potent antitubercular properties
SJ Tantry, G Degiacomi, S Sharma, L kumar Jena, A Narayan, S Guptha, ...
Bioorganic & medicinal chemistry letters 25 (16), 3234-3245, 2015
462015
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK
LR Chiarelli, G Mori, BS Orena, M Esposito, T Lane, ...
Scientific reports 8 (1), 3187, 2018
412018
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors
M Esposito, S Szadocka, G Degiacomi, BS Orena, G Mori, V Piano, ...
ACS Infectious Diseases 3 (6), 428-437, 2017
322017
Micrococcin P1–A bactericidal thiopeptide active against Mycobacterium tuberculosis
G Degiacomi, Y Personne, G Mondésert, X Ge, CS Mandava, ...
Tuberculosis 100, 95-101, 2016
302016
The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis
LA Rosado, K Wahni, G Degiacomi, B Pedre, D Young, AG De la Rubia, ...
Journal of Biological Chemistry 292 (32), 13097-13110, 2017
282017
Towards real-time and affordable strain-level metagenomics-based foodborne outbreak investigations using Oxford nanopore sequencing technologies
FE Buytaers, A Saltykova, S Denayer, B Verhaegen, K Vanneste, ...
Frontiers in Microbiology 12, 738284, 2021
212021
First triclosan-based macrocyclic inhibitors of InhA enzyme
F Rodriguez, N Saffon, JC Sammartino, G Degiacomi, MR Pasca, ...
Bioorganic Chemistry 95, 103498, 2020
192020
Promoter mutagenesis for fine‐tuning expression of essential genes in Mycobacterium tuberculosis
F Boldrin, G Degiacomi, A Serafini, GS Kolly, M Ventura, C Sala, ...
Microbial biotechnology 11 (1), 238-247, 2018
142018
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