Philip A. Romero
Philip A. Romero
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Zitiert von
Zitiert von
Exploring protein fitness landscapes by directed evolution
PA Romero, FH Arnold
Nature reviews Molecular cell biology 10 (12), 866-876, 2009
Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution
JD Bloom, PA Romero, Z Lu, FH Arnold
Biology direct 2 (1), 17, 2007
Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine
MG Shapiro, GG Westmeyer, PA Romero, JO Szablowski, B Küster, ...
Nature biotechnology 28 (3), 264-270, 2010
Navigating the protein fitness landscape with Gaussian processes
PA Romero, A Krause, FH Arnold
Proceedings of the National Academy of Sciences 110 (3), E193-E201, 2013
Dissecting enzyme function with microfluidic-based deep mutational scanning
PA Romero, TM Tran, AR Abate
Proceedings of the National Academy of Sciences 112 (23), 7159-7164, 2015
Efficient screening of fungal cellobiohydrolase class I enzymes for thermostabilizing sequence blocks by SCHEMA structure-guided recombination
P Heinzelman, R Komor, A Kanaan, P Romero, X Yu, S Mohler, C Snow, ...
Protein Engineering, Design & Selection 23 (11), 871-880, 2010
Highly thermostable fungal cellobiohydrolase I (Cel7A) engineered using predictive methods
RS Komor, PA Romero, CB Xie, FH Arnold
Protein engineering, design & selection 25 (12), 827-833, 2012
SCHEMA-designed variants of human arginase I and II reveal sequence elements important to stability and catalysis
PA Romero, E Stone, C Lamb, L Chantranupong, A Krause, AE Miklos, ...
ACS synthetic biology 1 (6), 221-228, 2012
In vivo selection of a computationally designed SCHEMA AAV library yields a novel variant for infection of adult neural stem cells in the SVZ
DS Ojala, S Sun, JL Santiago-Ortiz, MG Shapiro, PA Romero, DV Schaffer
Molecular Therapy 26 (1), 304-319, 2018
Flow focusing geometry generates droplets through a plug and squeeze mechanism
PA Romero, AR Abate
Lab on a Chip 12 (24), 5130-5132, 2012
Chimeragenesis of distantly‐related proteins by noncontiguous recombination
MA Smith, PA Romero, T Wu, EM Brustad, FH Arnold
Protein science 22 (2), 231-238, 2013
Efficient sampling of SCHEMA chimera families to identify useful sequence elements
P Heinzelman, PA Romero, FH Arnold
Methods in enzymology 523, 351-368, 2013
Microbial interaction network inference in microfluidic droplets
RH Hsu, RL Clark, JW Tan, JC Ahn, S Gupta, PA Romero, OS Venturelli
Cell systems 9 (3), 229-242. e4, 2019
Random field model reveals structure of the protein recombinational landscape
PA Romero, FH Arnold
PLoS Comput Biol 8 (10), e1002713, 2012
Directed evolution of protein-based neurotransmitter sensors for MRI
PA Romero, MG Shapiro, FH Arnold, A Jasanoff
Chemical Neurobiology, 193-205, 2013
Shaping it up: Design and engineering of biominerals and crystalline materials from the bottom up
J Seto, PA Romero
Biomineralization and Biomaterials, 3-50, 2016
Investigating the dynamics of microbial consortia in spatially structured environments
S Gupta, TD Ross, MM Gomez, JL Grant, PA Romero, OS Venturelli
Nature communications 11 (1), 1-15, 2020
Inferring protein sequence-function relationships with large-scale positive-unlabeled learning
H Song, BJ Bremer, EC Hinds, G Raskutti, PA Romero
bioRxiv, 2020
Adeno-associated virus capsid variants and methods of use thereof
DV Schaffer, DS Ojala, PA Romero
US Patent App. 16/500,706, 2020
Discovery of human ACE2 variants with altered recognition by the SARS-CoV-2 spike protein
P Heinzelman, PA Romero
bioRxiv, 2020
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