| Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft MM Mohiuddin, AK Singh, PC Corcoran, ML Thomas III, T Clark, BG Lewis, ... Nature communications 7 (1), 11138, 2016 | 436 | 2016 |
| Consistent success in life-supporting porcine cardiac xenotransplantation M Längin, T Mayr, B Reichart, S Michel, S Buchholz, S Guethoff, ... Nature 564 (7736), 430-433, 2018 | 433 | 2018 |
| Transgenic pigs as models for translational biomedical research B Aigner, S Renner, B Kessler, N Klymiuk, M Kurome, A Wünsch, E Wolf Journal of molecular medicine 88, 653-664, 2010 | 345 | 2010 |
| Genetic modification of pigs as organ donors for xenotransplantation N Klymiuk, B Aigner, G Brem, E Wolf Molecular Reproduction and Development: Incorporating Gamete Research 77 (3 …, 2010 | 256 | 2010 |
| Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy A Moretti, L Fonteyne, F Giesert, P Hoppmann, AB Meier, T Bozoglu, ... Nature medicine 26 (2), 207-214, 2020 | 201 | 2020 |
| Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle N Klymiuk, A Blutke, A Graf, S Krause, K Burkhardt, A Wuensch, S Krebs, ... Human molecular genetics 22 (21), 4368-4382, 2013 | 181 | 2013 |
| Animal models of arrhythmia: classic electrophysiology to genetically modified large animals S Clauss, C Bleyer, D Schuettler, P Tomsits, S Renner, N Klymiuk, ... Nature Reviews Cardiology 16 (8), 457-475, 2019 | 180 | 2019 |
| Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy AP Regensburger, LM Fonteyne, J Jüngert, AL Wagner, T Gerhalter, ... Nature medicine 25 (12), 1905-1915, 2019 | 157 | 2019 |
| Xenografted Islet Cell Clusters From INSLEA29Y Transgenic Pigs Rescue Diabetes and Prevent Immune Rejection in Humanized Mice N Klymiuk, L Van Buerck, A Bähr, M Offers, B Kessler, A Wuensch, ... Diabetes 61 (6), 1527-1532, 2012 | 153 | 2012 |
| One-year heterotopic cardiac xenograft survival in a pig to baboon model MM Mohiuddin, AK Singh, PC Corcoran, RF Hoyt, ML Thomas III, ... American journal of transplantation: official journal of the American …, 2014 | 125 | 2014 |
| Permanent Neonatal Diabetes in INSC94Y Transgenic Pigs S Renner, C Braun-Reichhart, A Blutke, N Herbach, D Emrich, E Streckel, ... Diabetes 62 (5), 1505-1511, 2013 | 123 | 2013 |
| OCT4/POU5F1 is required for NANOG expression in bovine blastocysts K Simmet, V Zakhartchenko, J Philippou-Massier, H Blum, N Klymiuk, ... Proceedings of the National Academy of Sciences 115 (11), 2770-2775, 2018 | 119 | 2018 |
| Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis N Klymiuk, L Mundhenk, K Kraehe, A Wuensch, S Plog, D Emrich, ... Journal of molecular medicine 90, 597-608, 2012 | 108 | 2012 |
| The normal trachea is cleaned by MUC5B mucin bundles from the submucosal glands coated with the MUC5AC mucin A Ermund, LN Meiss, AM Rodriguez-Pineiro, A Bähr, HE Nilsson, ... Biochemical and biophysical research communications 492 (3), 331-337, 2017 | 107 | 2017 |
| Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set M Kurome, L Geistlinger, B Kessler, V Zakhartchenko, N Klymiuk, ... BMC biotechnology 13, 1-13, 2013 | 102 | 2013 |
| Pig‐to‐baboon heterotopic heart transplantation–exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade … H Iwase, B Ekser, V Satyananda, J Bhama, H Hara, M Ezzelarab, E Klein, ... Xenotransplantation 22 (3), 211-220, 2015 | 98 | 2015 |
| Human engineered heart tissue patches remuscularize the injured heart in a dose-dependent manner E Querdel, M Reinsch, L Castro, D Köse, A Bähr, S Reich, B Geertz, ... Circulation 143 (20), 1991-2006, 2021 | 87 | 2021 |
| Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single-and multitransgenic pigs A Wuensch, A Baehr, AK Bongoni, E Kemter, A Blutke, W Baars, S Haertle, ... Transplantation 97 (2), 138-147, 2014 | 83 | 2014 |
| Vessel Network Architecture of Adult Human Islets Promotes Distinct Cell-Cell Interactions In Situ and Is Altered After Transplantation CM Cohrs, C Chen, SR Jahn, J Stertmann, H Chmelova, J Weitz, A Bähr, ... Endocrinology 158 (5), 1373-1385, 2017 | 82 | 2017 |
| First inducible transgene expression in porcine large animal models N Klymiuk, W Böcker, V Schönitzer, A Bahr, T Radic, T Fröhlich, A Wünsch, ... The FASEB Journal 26 (3), 1086-1099, 2012 | 71 | 2012 |
Eckhard WolfProfessor of Molecular Animal Breeding and BiotechnologyVerified email at genzentrum.lmu.de
