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Thomas J. Schmidt
Thomas J. Schmidt
Professor for Pharmaceutical Biology and Phytochemistry, University of Münster
Bestätigte E-Mail-Adresse bei uni-muenster.de - Startseite
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Zitiert von
Zitiert von
Jahr
The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κB by directly targeting p65
G Lyß, A Knorre, TJ Schmidt, HL Pahl, I Merfort
Journal of Biological Chemistry 273 (50), 33508-33516, 1998
6271998
Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity …
D Tasdemir, M Kaiser, R Brun, V Yardley, TJ Schmidt, F Tosun, P Rüedi
Antimicrobial agents and chemotherapy 50 (4), 1352-1364, 2006
6262006
Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones
AJ Garcı́a-Piñeres, V Castro, G Mora, TJ Schmidt, E Strunck, HL Pahl, ...
Journal of Biological Chemistry 276 (43), 39713-39720, 2001
5152001
The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-Part II
TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves, MW Biavatti, R Brun, ...
Curr. Med. Chem 19, 2176-2228, 2012
3852012
Inhibition of transcription factor NF-κB by sesquiterpene lactones: a proposed molecular mechanism of action
P Rüngeler, V Castro, G Mora, N Gören, W Vichnewski, HL Pahl, I Merfort, ...
Bioorganic & medicinal chemistry 7 (11), 2343-2352, 1999
3661999
Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-κB
G Lyss, TJ Schmidt, I Merfort, HL Pahl
Biological chemistry 378 (9), 951-962, 1997
3631997
Toxic activities of sesquiterpene lactones: structural and biochemical aspects
TJ Schmidt
Curr. Org. Chem 3 (577-608), 4, 1999
2281999
Helenanolide-type sesquiterpene lactones—III. Rates and stereochemistry in the reaction of helenalin and related helenanolides with sulfhydryl containing biomolecules
TJ Schmidt
Bioorganic & medicinal chemistry 5 (4), 645-653, 1997
1801997
Reactivity of dimethyl fumarate and methylhydrogen fumarate towards glutathione and N-acetyl-l-cysteine—preparation of S-substituted thiosuccinic acid esters
TJ Schmidt, M Ak, U Mrowietz
Bioorganic & medicinal chemistry 15 (1), 333-342, 2007
1782007
Pharmacological properties of the extract and some isolated compounds of Clausena lansium stem bark: anti-trichomonal, antidiabetic, anti-inflammatory, hepatoprotective and …
AC Adebajo, EO Iwalewa, EM Obuotor, GF Ibikunle, NO Omisore, ...
Journal of ethnopharmacology 122 (1), 10-19, 2009
1752009
Structure-cytotoxicity relationships of some helenanolide-type sesquiterpene lactones
AC Beekman, HJ Woerdenbag, W van Uden, N Pras, AWT Konings, ...
Journal of natural products 60 (3), 252-257, 1997
1611997
Structure-activity relationships of sesquiterpene lactones
TJ Schmidt
Studies in natural products chemistry 33, 309-392, 2006
1582006
The influence of glutathione and cysteine levels on the cytotoxicity of helenanolide type sesquiterpene lactones against KB cells
J Heilmann, MR Wasescha, TJ Schmidt
Bioorganic & medicinal chemistry 9 (8), 2189-2194, 2001
1482001
Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines.
HJ Woerdenbag, I Merfort, CM Passreiter, TJ Schmidt, G Willuhn, ...
Planta medica 60 (5), 434-437, 1994
1461994
Quantitative structure‒antiprotozoal activity relationships of sesquiterpene lactones
TJ Schmidt, AMM Nour, SA Khalid, M Kaiser, R Brun
Molecules 14 (6), 2062-2076, 2009
1392009
The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L.
AMM Nour, SA Khalid, M Kaiser, R Brun, EA Wai’l, TJ Schmidt
Journal of ethnopharmacology 129 (1), 127-130, 2010
1282010
Anti-trypanosomal activity of helenalin and some structurally related sesquiterpene lactones.
TJ Schmidt, R Brun, G Willuhn, SA Khalid
Planta medica 68 (8), 750-751, 2002
1232002
Detection of metabolites of fumaric acid esters in human urine: implications for their mode of action
M Rostami-Yazdi, B Clement, TJ Schmidt, D Schinor, U Mrowietz
Journal of Investigative Dermatology 129 (1), 231-234, 2009
1132009
Antileishmanial activity, cytotoxicity and QSAR analysis of synthetic dihydrobenzofuran lignans and related benzofurans
S Van Miert, S Van Dyck, TJ Schmidt, R Brun, A Vlietinck, G Lemière, ...
Bioorganic & medicinal chemistry 13 (3), 661-669, 2005
1062005
Helenanolide type sesquiterpene lactones. Part 5: the role of glutathione addition under physiological conditions
TJ Schmidt, G Lyß, HL Pahl, I Merfort
Bioorganic & medicinal chemistry 7 (12), 2849-2855, 1999
1051999
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