Timothy R. Hughes
Timothy R. Hughes
Verified email at utoronto.ca
TitleCited byYear
Functional discovery via a compendium of expression profiles
TR Hughes, MJ Marton, AR Jones, CJ Roberts, R Stoughton, CD Armour, ...
Cell 102 (1), 109-126, 2000
29292000
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae
NJ Krogan, G Cagney, H Yu, G Zhong, X Guo, A Ignatchenko, J Li, S Pu, ...
Nature 440 (7084), 637, 2006
28792006
Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer
TR Hughes, M Mao, AR Jones, J Burchard, MJ Marton, KW Shannon, ...
Nature biotechnology 19 (4), 342, 2001
15042001
Reverse transcriptase motifs in the catalytic subunit of telomerase
J Lingner, TR Hughes, A Shevchenko, M Mann, V Lundblad, TR Cech
Science 276 (5312), 561-567, 1997
13951997
The DNA-encoded nucleosome organization of a eukaryotic genome
N Kaplan, IK Moore, Y Fondufe-Mittendorf, AJ Gossett, D Tillo, Y Field, ...
Nature 458 (7236), 362, 2009
11242009
Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles
CJ Roberts, B Nelson, MJ Marton, R Stoughton, MR Meyer, HA Bennett, ...
Science 287 (5454), 873-880, 2000
9792000
A high-resolution atlas of nucleosome occupancy in yeast
W Lee, D Tillo, N Bray, RH Morse, RW Davis, TR Hughes, C Nislow
Nature genetics 39 (10), 1235, 2007
8682007
Diversity and complexity in DNA recognition by transcription factors
G Badis, MF Berger, AA Philippakis, S Talukder, AR Gehrke, SA Jaeger, ...
Science 324 (5935), 1720-1723, 2009
8182009
A compendium of RNA-binding motifs for decoding gene regulation
D Ray, H Kazan, KB Cook, MT Weirauch, HS Najafabadi, X Li, ...
Nature 499 (7457), 172, 2013
7892013
Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function
E Lécuyer, H Yoshida, N Parthasarathy, C Alm, T Babak, T Cerovina, ...
Cell 131 (1), 174-187, 2007
7792007
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex
MC Keogh, SK Kurdistani, SA Morris, SH Ahn, V Podolny, SR Collins, ...
Cell 123 (4), 593-605, 2005
7412005
DNA-binding specificities of human transcription factors
A Jolma, J Yan, T Whitington, J Toivonen, KR Nitta, P Rastas, ...
Cell 152 (1-2), 327-339, 2013
7332013
The human splicing code reveals new insights into the genetic determinants of disease
HY Xiong, B Alipanahi, LJ Lee, H Bretschneider, D Merico, RKC Yuen, ...
Science 347 (6218), 1254806, 2015
6562015
Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways
AB Parsons, RL Brost, H Ding, Z Li, C Zhang, B Sheikh, GW Brown, ...
Nature biotechnology 22 (1), 62, 2004
6352004
A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1
NJ Krogan, MC Keogh, N Datta, C Sawa, OW Ryan, H Ding, RA Haw, ...
Molecular cell 12 (6), 1565-1576, 2003
6322003
Determination and inference of eukaryotic transcription factor sequence specificity
MT Weirauch, A Yang, M Albu, AG Cote, A Montenegro-Montero, P Drewe, ...
Cell 158 (6), 1431-1443, 2014
6192014
Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance
CI Nugent, TR Hughes, NF Lue, V Lundblad
Science 274 (5285), 249-252, 1996
6151996
Mapping pathways and phenotypes by systematic gene overexpression
R Sopko, D Huang, N Preston, G Chua, B Papp, K Kafadar, M Snyder, ...
Molecular cell 21 (3), 319-330, 2006
5892006
Exploration of essential gene functions via titratable promoter alleles
S Mnaimneh, AP Davierwala, J Haynes, J Moffat, WT Peng, W Zhang, ...
Cell 118 (1), 31-44, 2004
5742004
Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences
MF Berger, G Badis, AR Gehrke, S Talukder, AA Philippakis, ...
Cell 133 (7), 1266-1276, 2008
5302008
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Articles 1–20