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Ravi Kumar Verma
Ravi Kumar Verma
Senior Scientist I, Bioinformatics Institute, ASTAR
Verified email at bii.a-star.edu.sg
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Cited by
Cited by
Year
Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signaling
Y Zhuang, H Liu, X Edward Zhou, R Kumar Verma, PW de Waal, W Jang, ...
Nature communications 11 (1), 885, 2020
932020
Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D3 Receptor
M Michino, CA Boateng, P Donthamsetti, H Yano, OM Bakare, A Bonifazi, ...
Journal of medicinal chemistry 60 (2), 580-593, 2017
532017
MIPModDB: a central resource for the superfamily of major intrinsic proteins
AB Gupta, RK Verma, V Agarwal, M Vajpai, V Bansal, ...
Nucleic acids research 40 (D1), D362-D369, 2012
502012
Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor
H Yano, NS Cai, M Xu, RK Verma, W Rea, AF Hoffman, L Shi, JA Javitch, ...
Nature communications 9 (1), 486, 2018
442018
A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity
M Sanchez-Soto, RK Verma, BKA Willette, EC Gonye, AM Moore, ...
Science signaling 13 (617), eaaw5885, 2020
352020
New subfamilies of major intrinsic proteins in fungi suggest novel transport properties in fungal channels: implications for the host-fungal interactions
RK Verma, ND Prabh, R Sankararamakrishnan
BMC evolutionary biology 14, 1-16, 2014
332014
Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism
JR Lane, AM Abramyan, P Adhikari, AC Keen, KH Lee, J Sanchez, ...
Elife 9, e52189, 2020
322020
The structural determinants of the bitopic binding mode of a negative allosteric modulator of the dopamine D2 receptor
CJ Draper-Joyce, M Michino, RK Verma, CK Herenbrink, J Shonberg, ...
Biochemical pharmacology 148, 315-328, 2018
282018
Major intrinsic protein superfamily: channels with unique structural features and diverse selectivity filters
RK Verma, AB Gupta, R Sankararamakrishnan
Methods in Enzymology 557, 485-520, 2015
272015
Molecular determinants of the intrinsic efficacy of the antipsychotic aripiprazole
C Klein Herenbrink, R Verma, HD Lim, A Kopinathan, A Keen, J Shonberg, ...
ACS chemical biology 14 (8), 1780-1792, 2019
242019
The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors
RK Verma, AM Abramyan, M Michino, RB Free, DR Sibley, JA Javitch, ...
PLoS Computational Biology 14 (1), e1005948, 2018
202018
Intra-helical salt-bridge and helix destabilizing residues within the same helical turn: Role of functionally important loop E half-helix in channel regulation of major …
RK Verma, ND Prabh, R Sankararamakrishnan
Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (6), 1436-1449, 2015
202015
Infigratinib is a reversible inhibitor and mechanism-based inactivator of cytochrome P450 3A4
LWT Tang, JW Teng, RK Verma, SK Koh, L Zhou, ML Go, H Fan, ...
Drug Metabolism and Disposition 49 (9), 856-868, 2021
172021
The action of a negative allosteric modulator at the dopamine D2 receptor is dependent upon sodium ions
CJ Draper-Joyce, RK Verma, M Michino, J Shonberg, A Kopinathan, ...
Scientific Reports 8 (1), 1208, 2018
162018
Recent advances in structure, function, and pharmacology of class A lipid GPCRs: opportunities and challenges for drug discovery
RNV Krishna Deepak, RK Verma, YD Hartono, WS Yew, H Fan
Pharmaceuticals 15 (1), 12, 2021
142021
Mechanism-based inactivation of cytochrome P450 3A4 by benzbromarone
LWT Tang, RK Verma, H Fan, ECY Chan
Molecular Pharmacology 99 (4), 266-276, 2021
142021
Evidence for a Stereoselective Mechanism for Bitopic Activity by Extended-Length Antagonists of the D3 Dopamine Receptor
AE Moritz, A Bonifazi, AM Guerrero, V Kumar, RB Free, JR Lane, ...
ACS chemical neuroscience 11 (20), 3309-3320, 2020
142020
Direct and Sequential Bioactivation of Pemigatinib to Reactive Iminium Ion Intermediates Culminates in Mechanism-Based Inactivation of Cytochrome P450 3A
LWT Tang, W Wei, RK Verma, SK Koh, L Zhou, H Fan, ECY Chan
Drug Metabolism and Disposition 50 (5), 529-540, 2022
122022
Atypical kinetics of cytochrome P450 2J2: epoxidation of arachidonic acid and reversible inhibition by xenobiotic inhibitors
JWH Leow, RK Verma, ABH Lim, H Fan, ECY Chan
European Journal of Pharmaceutical Sciences 164, 105889, 2021
102021
Differential reversible and irreversible interactions between benzbromarone and human cytochrome P450s 3A4 and 3A5
LWT Tang, RK Verma, RP Yong, X Li, L Wang, Q Lin, H Fan, ECY Chan
Molecular Pharmacology 100 (3), 224-236, 2021
82021
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