Fitness and stability of obligate cross-feeding interactions that emerge upon gene loss in bacteria S Pande, H Merker, K Bohl, M Reichelt, S Schuster, LF De Figueiredo, ... The ISME journal 8 (5), 953-962, 2014 | 235 | 2014 |
Computing the shortest elementary flux modes in genome-scale metabolic networks LF De Figueiredo, A Podhorski, A Rubio, C Kaleta, JE Beasley, ... Bioinformatics 25 (23), 3158-3165, 2009 | 214 | 2009 |
Less is more: selective advantages can explain the prevalent loss of biosynthetic genes in bacteria G D'Souza, S Waschina, S Pande, K Bohl, C Kaleta, C Kost Evolution 68 (9), 2559-2570, 2014 | 192 | 2014 |
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19 JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ... Immunity 53 (6), 1296-1314. e9, 2020 | 147 | 2020 |
BacArena: Individual-based metabolic modeling of heterogeneous microbes in complex communities E Bauer, J Zimmermann, F Baldini, I Thiele, C Kaleta PLoS computational biology 13 (5), e1005544, 2017 | 143 | 2017 |
Metabolic costs of amino acid and protein production in Escherichia coli C Kaleta, S Schäuble, U Rinas, S Schuster Biotechnology journal 8 (9), 1105-1114, 2013 | 138 | 2013 |
Metabolic functions of gut microbes associate with efficacy of tumor necrosis factor antagonists in patients with inflammatory bowel diseases K Aden, A Rehman, S Waschina, WH Pan, A Walker, M Lucio, AM Nunez, ... Gastroenterology 157 (5), 1279-1292. e11, 2019 | 132 | 2019 |
Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy R Pryor, P Norvaisas, G Marinos, L Best, LB Thingholm, LM Quintaneiro, ... Cell 178 (6), 1299-1312. e29, 2019 | 128 | 2019 |
Can the whole be less than the sum of its parts? Pathway analysis in genome-scale metabolic networks using elementary flux patterns C Kaleta, LF de Figueiredo, S Schuster Genome research 19 (10), 1872-1883, 2009 | 125 | 2009 |
Optimal regulatory strategies for metabolic pathways in Escherichia coli depending on protein costs F Wessely, M Bartl, R Guthke, P Li, S Schuster, C Kaleta Molecular systems biology 7 (1), 515, 2011 | 122 | 2011 |
Branched-chain amino acid catabolism is a conserved regulator of physiological ageing J Mansfeld, N Urban, S Priebe, M Groth, C Frahm, N Hartmann, ... Nature communications 6 (1), 1-12, 2015 | 108 | 2015 |
Integrated network reconstruction, visualization and analysis using YANAsquare R Schwarz, C Liang, C Kaleta, M Kühnel, E Hoffmann, S Kuznetsov, ... BMC bioinformatics 8 (1), 1-10, 2007 | 94 | 2007 |
Can sugars be produced from fatty acids? A test case for pathway analysis tools LF De Figueiredo, S Schuster, C Kaleta, DA Fell Bioinformatics 24 (22), 2615-2621, 2008 | 93 | 2008 |
Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly P Aramillo Irizar, S Schäuble, D Esser, M Groth, C Frahm, S Priebe, ... Nature communications 9 (1), 1-11, 2018 | 86 | 2018 |
Pervasive selection for cooperative cross-feeding in bacterial communities S Germerodt, K Bohl, A Lück, S Pande, A Schröter, C Kaleta, S Schuster, ... PLoS computational biology 12 (6), e1004986, 2016 | 74 | 2016 |
Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease R Häsler, R Sheibani-Tezerji, A Sinha, M Barann, A Rehman, D Esser, ... Gut 66 (12), 2087-2097, 2017 | 68 | 2017 |
Computing chemical organizations in biological networks F Centler, C Kaleta, PS di Fenizio, P Dittrich Bioinformatics 24 (14), 1611-1618, 2008 | 62 | 2008 |
EFMEvolver: Computing elementary flux modes in genome-scale metabolic networks C Kaleta, LF Figueiredo, J Behre, S Schuster German conference on bioinformatics 2009, 2009 | 57 | 2009 |
Mathematical models for explaining the Warburg effect: a review focussed on ATP and biomass production S Schuster, D Boley, P Möller, H Stark, C Kaleta Biochemical Society Transactions 43 (6), 1187-1194, 2015 | 55 | 2015 |
Inhibition of alanine aminotransferase in silico and in vivo promotes mitochondrial metabolism to impair malignant growth G Beuster, K Zarse, C Kaleta, R Thierbach, M Kiehntopf, P Steinberg, ... Journal of Biological Chemistry 286 (25), 22323-22330, 2011 | 55 | 2011 |