Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19 JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ... Immunity 53 (6), 1296-1314. e9, 2020 | 332 | 2020 |
Fitness and stability of obligate cross-feeding interactions that emerge upon gene loss in bacteria S Pande, H Merker, K Bohl, M Reichelt, S Schuster, LF De Figueiredo, ... The ISME journal 8 (5), 953-962, 2014 | 330 | 2014 |
BacArena: Individual-based metabolic modeling of heterogeneous microbes in complex communities E Bauer, J Zimmermann, F Baldini, I Thiele, C Kaleta PLoS computational biology 13 (5), e1005544, 2017 | 267 | 2017 |
Less is more: selective advantages can explain the prevalent loss of biosynthetic genes in bacteria G D'Souza, S Waschina, S Pande, K Bohl, C Kaleta, C Kost Evolution 68 (9), 2559-2570, 2014 | 263 | 2014 |
Metabolic functions of gut microbes associate with efficacy of tumor necrosis factor antagonists in patients with inflammatory bowel diseases K Aden, A Rehman, S Waschina, WH Pan, A Walker, M Lucio, AM Nunez, ... Gastroenterology 157 (5), 1279-1292. e11, 2019 | 249 | 2019 |
Computing the shortest elementary flux modes in genome-scale metabolic networks LF De Figueiredo, A Podhorski, A Rubio, C Kaleta, JE Beasley, ... Bioinformatics 25 (23), 3158-3165, 2009 | 235 | 2009 |
Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy R Pryor, P Norvaisas, G Marinos, L Best, LB Thingholm, LM Quintaneiro, ... Cell 178 (6), 1299-1312. e29, 2019 | 223 | 2019 |
Metabolic costs of amino acid and protein production in Escherichia coli C Kaleta, S Schäuble, U Rinas, S Schuster Biotechnology journal 8 (9), 1105-1114, 2013 | 200 | 2013 |
Gapseq: informed prediction of bacterial metabolic pathways and reconstruction of accurate metabolic models J Zimmermann, C Kaleta, S Waschina Genome biology 22, 1-35, 2021 | 161 | 2021 |
Branched-chain amino acid catabolism is a conserved regulator of physiological ageing J Mansfeld, N Urban, S Priebe, M Groth, C Frahm, N Hartmann, ... Nature communications 6 (1), 10043, 2015 | 152 | 2015 |
CeMbio - The Caenorhabditis elegans Microbiome Resource P Dirksen, A Assié, J Zimmermann, F Zhang, AM Tietje, SA Marsh, ... G3: Genes, Genomes, Genetics 10 (9), 3025-3039, 2020 | 143 | 2020 |
Can the whole be less than the sum of its parts? Pathway analysis in genome-scale metabolic networks using elementary flux patterns C Kaleta, LF de Figueiredo, S Schuster Genome research 19 (10), 1872-1883, 2009 | 138 | 2009 |
Optimal regulatory strategies for metabolic pathways in Escherichia coli depending on protein costs F Wessely, M Bartl, R Guthke, P Li, S Schuster, C Kaleta Molecular systems biology 7 (1), 515, 2011 | 135 | 2011 |
Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly P Aramillo Irizar, S Schäuble, D Esser, M Groth, C Frahm, S Priebe, ... Nature communications 9 (1), 327, 2018 | 121 | 2018 |
Pervasive selection for cooperative cross-feeding in bacterial communities S Germerodt, K Bohl, A Lück, S Pande, A Schröter, C Kaleta, S Schuster, ... PLoS computational biology 12 (6), e1004986, 2016 | 119 | 2016 |
Natural C. elegans microbiota protects against infection via production of a cyclic lipopeptide of the viscosin group KAB Kissoyan, M Drechsler, EL Stange, J Zimmermann, C Kaleta, ... Current Biology 29 (6), 1030-1037. e5, 2019 | 112 | 2019 |
Can sugars be produced from fatty acids? A test case for pathway analysis tools LF De Figueiredo, S Schuster, C Kaleta, DA Fell Bioinformatics 24 (22), 2615-2621, 2008 | 105 | 2008 |
In vitro interaction network of a synthetic gut bacterial community AS Weiss, AG Burrichter, AC Durai Raj, A von Strempel, C Meng, ... The ISME journal 16 (4), 1095-1109, 2022 | 103 | 2022 |
Sugar-induced obesity and insulin resistance are uncoupled from shortened survival in Drosophila E van Dam, LAG van Leeuwen, E Dos Santos, J James, L Best, ... Cell metabolism 31 (4), 710-725. e7, 2020 | 101 | 2020 |
Integrated network reconstruction, visualization and analysis using YANAsquare R Schwarz, C Liang, C Kaleta, M Kühnel, E Hoffmann, S Kuznetsov, ... BMC bioinformatics 8, 1-10, 2007 | 96 | 2007 |