Young-Bum Kim
Young-Bum Kim
Harvard Medical School
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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
Y Minokoshi, YB Kim, OD Peroni, LGD Fryer, C Müller, D Carling, ...
Nature 415 (6869), 339-343, 2002
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
Y Minokoshi, T Alquier, N Furukawa, YB Kim, A Lee, B Xue, J Mu, ...
Nature 428 (6982), 569-574, 2004
Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice
LD Klaman, O Boss, OD Peroni, JK Kim, JL Martino, JM Zabolotny, ...
Molecular and cellular biology 20 (15), 5479-5489, 2000
Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver
ED Abel, O Peroni, JK Kim, YB Kim, O Boss, E Hadro, T Minnemann, ...
Nature 409 (6821), 729-733, 2001
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β cell dysfunction, and type 2 diabetes
CY Zhang, G Baffy, P Perret, S Krauss, O Peroni, D Grujic, T Hagen, ...
Cell 105 (6), 745-755, 2001
PTP1B regulates leptin signal transduction in vivo
JM Zabolotny, KK Bence-Hanulec, A Stricker-Krongrad, F Haj, Y Wang, ...
Developmental cell 2 (4), 489-495, 2002
Differential effects of interleukin-6 and-10 on skeletal muscle and liver insulin action in vivo
HJ Kim, T Higashimori, SY Park, H Choi, J Dong, YJ Kim, HL Noh, ...
Diabetes 53 (4), 1060-1067, 2004
Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes
YB Kim, SE Nikoulina, TP Ciaraldi, RR Henry, BB Kahn
Journal of Clinical Investigation 104 (6), 733-741, 1999
Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo
JM Zabolotny, YB Kim, LA Welsh, EE Kershaw, BG Neel, BB Kahn
Journal of biological chemistry 283 (21), 14230-14241, 2008
Abnormal glucose homeostasis in skeletal muscle-specific PGC-1 alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk
C Handschin, CS Choi, S Chin, S Kim, D Kawamori, AJ Kurpad, ...
Journal of Clinical Investigation 117 (11), 3463, 2007
In Vivo Administration of Leptin Activates Signal Transduction Directly in Insulin-Sensitive Tissues: Overlapping but Distinct Pathways from Insulin 1
YB Kim, S Uotani, DD Pierroz, JS Flier, BB Kahn
Endocrinology 141 (7), 2328-2339, 2000
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
MS Kim, YK Pak, PG Jang, C Namkoong, YS Choi, JC Won, KS Kim, ...
Nature neuroscience 9 (7), 901-906, 2006
Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice
SY Park, YR Cho, HJ Kim, T Higashimori, C Danton, MK Lee, A Dey, ...
Diabetes 54 (12), 3530-3540, 2005
Molecular mechanism of insulin resistance in obesity and type 2 diabetes
K Choi, YB Kim
The Korean journal of internal medicine 25 (2), 119-129, 2010
The mitogenic and antiapoptotic actions of ghrelin in 3T3-L1 adipocytes
MS Kim, CY Yoon, PG Jang, YJ Park, CS Shin, HS Park, JW Ryu, YK Pak, ...
Molecular Endocrinology 18 (9), 2291-2301, 2004
Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling
A Corbould, YB Kim, JF Youngren, C Pender, BB Kahn, A Lee, A Dunaif
American Journal of Physiology-Endocrinology and Metabolism 288 (5), E1047-E1054, 2005
Hypothalamic orexin stimulates feeding-associated glucose utilization in skeletal muscle via sympathetic nervous system
T Shiuchi, MS Haque, S Okamoto, T Inoue, H Kageyama, S Lee, C Toda, ...
Cell metabolism 10 (6), 466-480, 2009
Insulin-Stimulated Protein Kinase C λ/ζ Activity Is Reduced in Skeletal Muscle of Humans With Obesity and Type 2 Diabetes Reversal With Weight Reduction
YB Kim, K Kotani, TP Ciaraldi, RR Henry, BB Kahn
Diabetes 52 (8), 1935-1942, 2003
Hypomorphic mutation of PGC-1β causes mitochondrial dysfunction and liver insulin resistance
CR Vianna, M Huntgeburth, R Coppari, CS Choi, J Lin, S Krauss, ...
Cell metabolism 4 (6), 453-464, 2006
Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not …
JM Zabolotny, FG Haj, YB Kim, HJ Kim, GI Shulman, JK Kim, BG Neel, ...
Journal of Biological Chemistry 279 (23), 24844-24851, 2004
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