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Theodore Laetsch
Theodore Laetsch
Associate Professor of Pediatrics, Children's Hospital of Philadelphia
Verified email at chop.edu
Title
Cited by
Cited by
Year
Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia
SL Maude, TW Laetsch, J Buechner, S Rives, M Boyer, H Bittencourt, ...
New England Journal of Medicine 378 (5), 439-448, 2018
45692018
Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children
A Drilon, TW Laetsch, S Kummar, SG DuBois, UN Lassen, GD Demetri, ...
New England Journal of Medicine 378 (8), 731-739, 2018
24852018
Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials
DS Hong, SG DuBois, S Kummar, AF Farago, CM Albert, KS Rohrberg, ...
The Lancet Oncology 21 (4), 531-540, 2020
7732020
Comprehensive analysis of hypermutation in human cancer
BB Campbell, N Light, D Fabrizio, M Zatzman, F Fuligni, R de Borja, ...
Cell 171 (5), 1042-1056. e10, 2017
6912017
Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study
TW Laetsch, SG DuBois, L Mascarenhas, B Turpin, N Federman, ...
The Lancet Oncology 19 (5), 705-714, 2018
5042018
Real-world evidence of tisagenlecleucel for pediatric acute lymphoblastic leukemia and non-Hodgkin lymphoma
MC Pasquini, ZH Hu, K Curran, T Laetsch, F Locke, R Rouce, ...
Blood advances 4 (21), 5414-5424, 2020
3292020
Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of …
B Geoerger, HJ Kang, M Yalon-Oren, LV Marshall, C Vezina, A Pappo, ...
The Lancet Oncology 21 (1), 121-133, 2020
2422020
Clinical pharmacology of tisagenlecleucel in B-cell acute lymphoblastic leukemia
KT Mueller, E Waldron, SA Grupp, JE Levine, TW Laetsch, MA Pulsipher, ...
Clinical cancer research 24 (24), 6175-6184, 2018
2062018
Pan-Trk immunohistochemistry identifies NTRK rearrangements in pediatric mesenchymal tumors
ER Rudzinski, CM Lockwood, BA Stohr, SO Vargas, R Sheridan, JO Black, ...
The American journal of surgical pathology 42 (7), 927-935, 2018
1912018
Venetoclax and navitoclax in combination with chemotherapy in patients with relapsed or refractory acute lymphoblastic leukemia and lymphoblastic lymphoma
VA Pullarkat, NJ Lacayo, E Jabbour, JE Rubnitz, A Bajel, TW Laetsch, ...
Cancer discovery 11 (6), 1440-1453, 2021
1782021
The use of neoadjuvant larotrectinib in the management of children with locally advanced TRK fusion sarcomas
SG DuBois, TW Laetsch, N Federman, BK Turpin, CM Albert, ...
Cancer 124 (21), 4241-4247, 2018
1272018
Blinatumomab nonresponse and high-disease burden are associated with inferior outcomes after CD19-CAR for B-ALL
RM Myers, A Taraseviciute, SM Steinberg, AJ Lamble, J Sheppard, ...
Journal of Clinical Oncology 40 (9), 932, 2022
1232022
Updated analysis of the efficacy and safety of tisagenlecleucel in pediatric and young adult patients with relapsed/refractory (r/r) acute lymphoblastic leukemia
SA Grupp, SL Maude, S Rives, A Baruchel, MW Boyer, H Bittencourt, ...
Blood 132, 895, 2018
1162018
Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study
W Sun, J Malvar, R Sposto, A Verma, JJ Wilkes, R Dennis, K Heym, ...
Leukemia 32 (11), 2316-2325, 2018
1152018
Expanding the spectrum of pediatric NTRK-rearranged mesenchymal tumors
JL Davis, CM Lockwood, B Stohr, C Boecking, A Al-Ibraheemi, SG DuBois, ...
The American journal of surgical pathology 43 (4), 435-445, 2019
1132019
The efficacy of larotrectinib (LOXO-101), a selective tropomyosin receptor kinase (TRK) inhibitor, in adult and pediatric TRK fusion cancers.
DM Hyman, TW Laetsch, S Kummar, SG DuBois, AF Farago, AS Pappo, ...
Journal of Clinical Oncology 35 (15_suppl), LBA2501-LBA2501, 2017
1112017
Three-year update of tisagenlecleucel in pediatric and young adult patients with relapsed/refractory acute lymphoblastic leukemia in the ELIANA trial
TW Laetsch, SL Maude, S Rives, H Hiramatsu, H Bittencourt, P Bader, ...
Journal of Clinical Oncology 41 (9), 1664, 2023
1062023
Disease burden affects outcomes in pediatric and young adult B-cell lymphoblastic leukemia after commercial tisagenlecleucel: a pediatric real-world chimeric antigen receptor …
LM Schultz, C Baggott, S Prabhu, HL Pacenta, CL Phillips, J Rossoff, ...
Journal of Clinical Oncology 40 (9), 945, 2022
1062022
Abstract CT127: Phase I and expanded access experience of LOXO-195 (BAY 2731954), a selective next-generation TRK inhibitor (TRKi)
D Hyman, S Kummar, A Farago, B Geoerger, M Mau-Sorensen, M Taylor, ...
Cancer Research 79 (13_Supplement), CT127-CT127, 2019
1052019
Clinical utilization of chimeric antigen receptor T cells in B cell acute lymphoblastic leukemia: an expert opinion from the European Society for Blood and Marrow …
AJ Kansagra, NV Frey, M Bar, TW Laetsch, PA Carpenter, BN Savani, ...
Biology of blood and marrow transplantation 25 (3), e76-e85, 2019
1052019
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