| A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. 3 IPM Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, K Howarth, ... Nature genetics 40 (5), 623-630, 2008 | 637 | 2008 |
| Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome TC Pansuriya, R Van Eijk, P d'Adamo, MAJH Van Ruler, ML Kuijjer, ... Nature genetics 43 (12), 1256-1261, 2011 | 513 | 2011 |
| E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines M Lombaerts, T Van Wezel, K Philippo, JWF Dierssen, RME Zimmerman, ... British journal of cancer 94 (5), 661-671, 2006 | 427 | 2006 |
| Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer J Drost, R Van Boxtel, F Blokzijl, T Mizutani, N Sasaki, V Sasselli, J de Ligt, ... Science 358 (6360), 234-238, 2017 | 334 | 2017 |
| Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers CAL Ruivenkamp, T van Wezel, C Zanon, APM Stassen, C Vlcek, ... Nature genetics 31 (3), 295-300, 2002 | 296 | 2002 |
| Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study E Domingo, L Freeman-Mills, E Rayner, M Glaire, S Briggs, L Vermeulen, ... The lancet Gastroenterology & hepatology 1 (3), 207-216, 2016 | 237 | 2016 |
| A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3) V Enciso-Mora, P Broderick, Y Ma, RF Jarrett, H Hjalgrim, K Hemminki, ... Nature genetics 42 (12), 1126-1130, 2010 | 219 | 2010 |
| Rapid KRAS, EGFR, BRAF and PIK3CA Mutation Analysis of Fine Needle Aspirates from Non-Small-Cell Lung Cancer Using Allele-Specific qPCR R van Eijk, J Licht, M Schrumpf, M Talebian Yazdi, D Ruano, GI Forte, ... PloS one 6 (3), e17791, 2011 | 214 | 2011 |
| Practical guidance for mismatch repair-deficiency testing in endometrial cancer E Stelloo, AML Jansen, EM Osse, RA Nout, CL Creutzberg, D Ruano, ... Annals of Oncology 28 (1), 96-102, 2017 | 195 | 2017 |
| Gene interaction and single gene effects in colon tumour susceptibility in mice T Wezel, APM Stassen, CJA Moen, AAM Hart, MA van der Valk, P Demant Nature genetics 14 (4), 468-470, 1996 | 164 | 1996 |
| Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK PW Voorneveld, LL Kodach, RJ Jacobs, N Liv, AC Zonnevylle, ... Gastroenterology 147 (1), 196-208. e13, 2014 | 156 | 2014 |
| Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell ‘stemness’ via the bone morphogenetic … LL Kodach, RJ Jacobs, PW Voorneveld, ME Wildenberg, HW Verspaget, ... Gut 60 (11), 1544-1553, 2011 | 149 | 2011 |
| Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer JN Kloth, J Oosting, T van Wezel, K Szuhai, J Knijnenburg, A Gorter, ... BMC genomics 8 (1), 53, 2007 | 130 | 2007 |
| Expression of HLA class I antigen, aspirin use, and survival after a diagnosis of colon cancer MS Reimers, E Bastiaannet, RE Langley, R van Eijk, RLP van Vlierberghe, ... JAMA internal medicine 174 (5), 732-739, 2014 | 123 | 2014 |
| Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment YM Schrage, IH Briaire-de Bruijn, NFCC de Miranda, J van Oosterwijk, ... Cancer Research 69 (15), 6216-6222, 2009 | 119 | 2009 |
| HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression JWF Dierssen, NFCC de Miranda, S Ferrone, M van Puijenbroek, ... BMC cancer 7, 1-11, 2007 | 116 | 2007 |
| Mutational signature analysis reveals NTHL1 deficiency to cause a multi-tumor phenotype JE Grolleman, RM De Voer, FA Elsayed, M Nielsen, RDA Weren, C Palles, ... Cancer cell 35 (2), 256-266. e5, 2019 | 115 | 2019 |
| The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression AM Pittman, S Naranjo, E Webb, P Broderick, EH Lips, T Van Wezel, ... Genome research 19 (6), 987-993, 2009 | 114 | 2009 |
| Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer FA Elsayed, CM Kets, D Ruano, B Van Den Akker, AR Mensenkamp, ... European Journal of Human Genetics 23 (8), 1080-1084, 2015 | 112 | 2015 |
| Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers AML Jansen, T Van Wezel, BE Van Den Akker, M Ventayol Garcia, ... European Journal of Human Genetics 24 (7), 1089-1092, 2016 | 110 | 2016 |
Ronald van EijkClinical scientist in molecular pathology, in training , Leiden University Medical Center, LUMC, theBestätigte E-Mail-Adresse bei lumc.nl
