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Dustin J. Flanagan
Dustin J. Flanagan
Bestätigte E-Mail-Adresse bei monash.edu
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Zitiert von
Zitiert von
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NOTUM from Apc-mutant cells biases clonal competition to initiate cancer
DJ Flanagan, N Pentinmikko, K Luopajärvi, NJ Willis, K Gilroy, AP Raven, ...
Nature 594 (7863), 430-435, 2021
1582021
Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5+ stem cells
DJ Flanagan, TJ Phesse, N Barker, RHM Schwab, N Amin, J Malaterre, ...
Stem cell reports 4 (5), 759-767, 2015
1512015
PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis
A Sakthianandeswaren, M Christie, C D'Andreti, C Tsui, RN Jorissen, S Li, ...
Cancer research 71 (10), 3709-3719, 2011
1012011
Wnt signalling in gastrointestinal epithelial stem cells
DJ Flanagan, CR Austin, E Vincan, TJ Phesse
Genes 9 (4), 178, 2018
962018
Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations
DJ Flanagan, N Barker, NSD Costanzo, EA Mason, A Gurney, VS Meniel, ...
Cancer Research 79 (5), 970-981, 2019
902019
Frizzled7: a promising Achilles’ heel for targeting the Wnt receptor complex to treat cancer
T Phesse, D Flanagan, E Vincan
Cancers 8 (5), 50, 2016
832016
Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt–β-catenin–mediated intestinal tumor growth and regeneration
TJ Phesse, M Buchert, E Stuart, DJ Flanagan, M Faux, S Afshar-Sterle, ...
Science signaling 7 (345), ra92-ra92, 2014
762014
Wnt signaling in cancer: not a binary ON: OFF switch
DJ Flanagan, E Vincan, TJ Phesse
Cancer research 79 (23), 5901-5906, 2019
612019
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia
EG Vazquez, N Nasreddin, GN Valbuena, EJ Mulholland, ...
Cell Stem Cell 29 (8), 1213-1228. e8, 2022
572022
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression
JRP Knight, C Alexandrou, GL Skalka, N Vlahov, K Pennel, L Officer, ...
Cancer discovery 11 (5), 1228-1247, 2021
572021
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis
JDG Leach, N Vlahov, P Tsantoulis, RA Ridgway, DJ Flanagan, K Gilroy, ...
Nature communications 12 (1), 3464, 2021
502021
Calorie restriction increases the number of competing stem cells and decreases mutation retention in the intestine
L Bruens, SIJ Ellenbroek, SJE Suijkerbuijk, M Azkanaz, AJ Hale, ...
Cell reports 32 (3), 2020
482020
Retrograde movements determine effective stem cell numbers in the intestine
M Azkanaz, B Corominas-Murtra, SIJ Ellenbroek, L Bruens, AT Webb, ...
Nature 607 (7919), 548-554, 2022
442022
Stomach-specific activation of oncogenic KRAS and STAT3-dependent inflammation cooperatively promote gastric tumorigenesis in a preclinical model
S Thiem, MF Eissmann, J Elzer, A Jonas, TL Putoczki, A Poh, P Nguyen, ...
Cancer research 76 (8), 2277-2287, 2016
402016
Intestinal epithelial-specific PTEN inactivation results in tumor formation
DS Byun, N Ahmed, S Nasser, J Shin, S Al-Obaidi, S Goel, GA Corner, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 301 (5 …, 2011
392011
The core planar cell polarity gene prickle interacts with flamingo to promote sensory axon advance in the Drosophila embryo
EM Mrkusich, DJ Flanagan, PM Whitington
Developmental biology 358 (1), 224-230, 2011
382011
Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells
RHM Schwab, N Amin, DJ Flanagan, TM Johanson, TJ Phesse, E Vincan
Developmental Dynamics 247 (3), 521-530, 2018
372018
Winding back Wnt signalling: potential therapeutic targets for treating gastric cancers
DJ Flanagan, E Vincan, TJ Phesse
British journal of pharmacology 174 (24), 4666-4683, 2017
362017
Variable FZD7 expression in colorectal cancers indicates regulation by the tumour microenvironment
E Vincan, DJ Flanagan, N Pouliot, T Brabletz, S Spaderna
Developmental Dynamics: An Official Publication of the American Association …, 2010
352010
Expression of r-spondin 1 in ApcMin/+ mice suppresses growth of intestinal adenomas by altering wnt and transforming growth factor beta signaling
M Lähde, S Heino, J Högström, S Kaijalainen, A Anisimov, D Flanagan, ...
Gastroenterology 160 (1), 245-259, 2021
282021
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