| Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium N Robinson, S McComb, R Mulligan, R Dudani, L Krishnan, S Sad Nature immunology 13 (10), 954-962, 2012 | 474 | 2012 |
| Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or-7 S McComb, PK Chan, A Guinot, H Hartmannsdottir, S Jenni, MP Dobay, ... Science advances 5 (7), eaau9433, 2019 | 207 | 2019 |
| Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages S McComb, E Cessford, NA Alturki, J Joseph, B Shutinoski, JB Startek, ... Proceedings of the National Academy of Sciences 111 (31), E3206-E3213, 2014 | 199 | 2014 |
| cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation S McComb, HH Cheung, RG Korneluk, S Wang, L Krishnan, S Sad Cell Death & Differentiation 19 (11), 1791-1801, 2012 | 171 | 2012 |
| Introduction to the immune system S McComb, A Thiriot, B Akache, L Krishnan, F Stark Immunoproteomics: methods and protocols, 1-24, 2019 | 127 | 2019 |
| Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL S McComb, J Aguadé-Gorgorió, L Harder, B Marovca, G Cario, C Eckert, ... Science translational medicine 8 (339), 339ra70-339ra70, 2016 | 106 | 2016 |
| Cathepsins limit macrophage necroptosis through cleavage of Rip1 kinase S McComb, B Shutinoski, S Thurston, E Cessford, K Kumar, S Sad The Journal of Immunology 192 (12), 5671-5678, 2014 | 79 | 2014 |
| From mice to women: the conundrum of immunity to infection during pregnancy L Krishnan, T Nguyen, S McComb Journal of reproductive immunology 97 (1), 62-73, 2013 | 79 | 2013 |
| A high-throughput method for characterizing novel chimeric antigen receptors in Jurkat cells D Bloemberg, T Nguyen, S MacLean, A Zafer, C Gadoury, K Gurnani, ... Molecular Therapy-Methods & Clinical Development 16, 238-254, 2020 | 68 | 2020 |
| Caspase-3 is transiently activated without cell death during early antigen driven expansion of CD8+ T cells in vivo S McComb, R Mulligan, S Sad PloS one 5 (12), e15328, 2010 | 63 | 2010 |
| Introduction to the immune system S McComb, A Thiriot, L Krishnan, F Stark Immunoproteomics: Methods and Protocols, 1-20, 2013 | 52 | 2013 |
| MAP4K4 controlled integrin β1 activation and c-Met endocytosis are associated with invasive behavior of medulloblastoma cells D Tripolitsioti, KS Kumar, A Neve, J Migliavacca, C Capdeville, ... Oncotarget 9 (33), 23220, 2018 | 33 | 2018 |
| Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis NA Alturki, S McComb, A Ariana, D Rijal, RG Korneluk, SC Sun, E Alnemri, ... Cell death & disease 9 (6), 592, 2018 | 27 | 2018 |
| Differentiated macrophages acquire a pro-inflammatory and cell death–resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1 D Rijal, A Ariana, A Wight, K Kim, NA Alturki, Z Aamir, ES Ametepe, ... Journal of Biological Chemistry 293 (30), 11913-11927, 2018 | 24 | 2018 |
| Advancements in CAR-NK therapy: lessons to be learned from CAR-T therapy MK Kilgour, DJ Bastin, SH Lee, M Ardolino, S McComb, A Visram Frontiers in Immunology 14, 1166038, 2023 | 14 | 2023 |
| Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer MJF Crupi, Z Taha, TJA Janssen, J Petryk, S Boulton, N Alluqmani, ... Frontiers in Immunology 13, 1029269, 2022 | 14 | 2022 |
| Application of blood brain barrier models in pre-clinical assessment of glioblastoma-targeting CAR-T based immunotherapies J Huang, YB Li, C Charlebois, T Nguyen, Z Liu, D Bloemberg, A Zafer, ... Fluids and Barriers of the CNS 19 (1), 38, 2022 | 12 | 2022 |
| Identification of transcriptional subtypes in lung adenocarcinoma and squamous cell carcinoma through integrative analysis of microarray and RNA sequencing data F Fauteux, A Surendra, S McComb, Y Pan, JJ Hill Scientific reports 11 (1), 8709, 2021 | 10 | 2021 |
| TNFR2 is required for RIP1-dependent cell death in human leukemia J Aguadé-Gorgorió, S McComb, C Eckert, A Guinot, B Marovca, ... Blood advances 4 (19), 4823-4833, 2020 | 10 | 2020 |
| Programmable attenuation of antigenic sensitivity for a nanobody-based EGFR chimeric antigen receptor through hinge domain truncation S McComb, T Nguyen, A Shepherd, KA Henry, D Bloemberg, A Marcil, ... Frontiers in Immunology 13, 864868, 2022 | 9 | 2022 |
subash sadUniversity of OttawaBestätigte E-Mail-Adresse bei uottawa.ca
