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Laura Ganser
Laura Ganser
Postdoctoral Researcher, Johns Hopkins University
Verified email at duke.edu
Title
Cited by
Cited by
Year
The roles of structural dynamics in the cellular functions of RNAs
LR Ganser, ML Kelly, D Herschlag, HM Al-Hashimi
Nature reviews Molecular cell biology 20 (8), 474-489, 2019
3712019
TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A
XR Ma, M Prudencio, Y Koike, SC Vatsavayai, G Kim, F Harbinski, ...
Nature 603 (7899), 124-130, 2022
2382022
Glucose starvation inhibits autophagy via vacuolar hydrolysis and induces plasma membrane internalization by down-regulating recycling
MJ Lang, JY Martinez-Marquez, DC Prosser, LR Ganser, D Buelto, ...
Journal of Biological Chemistry 289 (24), 16736-16747, 2014
942014
High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble
LR Ganser, J Lee, A Rangadurai, DK Merriman, ML Kelly, AD Kansal, ...
Nature structural & molecular biology 25 (5), 425-434, 2018
842018
Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR
NN Patwardhan, LR Ganser, GJ Kapral, CS Eubanks, J Lee, ...
MedChemComm 8 (5), 1022-1036, 2017
782017
Development and application of aromatic [13C, 1H] SOFAST-HMQC NMR experiment for nucleic acids
B Sathyamoorthy, J Lee, I Kimsey, LR Ganser, H Al-Hashimi
Journal of biomolecular NMR 60, 77-83, 2014
452014
Poly (ADP-ribose) drives condensation of FUS via a transient interaction
K Rhine, M Dasovich, J Yoniles, M Badiee, S Skanchy, LR Ganser, Y Ge, ...
Molecular cell 82 (5), 969-985. e11, 2022
432022
Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics
MC Clay, LR Ganser, DK Merriman, HM Al-Hashimi
Nucleic acids research 45 (14), e134-e134, 2017
422017
Methods to study phase-separated condensates and the underlying molecular interactions
LR Ganser, S Myong
Trends in biochemical sciences 45 (11), 1004, 2020
352020
Probing RNA conformational equilibria within the functional cellular context
LR Ganser, CC Chu, HP Bogerd, ML Kelly, BR Cullen, HM Al-Hashimi
Cell reports 30 (8), 2472-2480. e4, 2020
342020
Demonstration that small molecules can bind and stabilize low-abundance short-lived RNA excited conformational states
LR Ganser, ML Kelly, NN Patwardhan, AE Hargrove, HM Al-Hashimi
Journal of molecular biology 432 (4), 1297-1304, 2020
272020
Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem–loop RNAs and their implications for functional cellular assays
ML Kelly, CC Chu, H Shi, LR Ganser, HP Bogerd, K Huynh, Y Hou, ...
Rna 27 (1), 12-26, 2021
172021
RNA conformational propensities determine cellular activity
ML Ken, R Roy, A Geng, LR Ganser, A Manghrani, BR Cullen, ...
Nature 617 (7962), 835-841, 2023
162023
HIV-1 leader RNA dimeric interface revealed by NMR
LR Ganser, HM Al-Hashimi
Proceedings of the National Academy of Sciences 113 (47), 13263-13265, 2016
62016
An RNA tertiary switch by modifying how helices are tethered
LR Ganser, AM Mustoe, HM Al-Hashimi
Genome biology 15, 1-3, 2014
52014
Switch-like compaction of poly (ADP-ribose) upon cation binding
M Badiee, AL Kenet, LR Ganser, T Paul, S Myong, AKL Leung
Proceedings of the National Academy of Sciences 120 (19), e2215068120, 2023
42023
Nucleation and dissolution mechanism underlying amyotrophic lateral sclerosis/frontotemporal lobar dementia-linked fused in sarcoma condensates
NA Djaja, MT Chang, FR Beinart, VM Morris, LR Ganser, S Myong
Iscience 26 (4), 2023
32023
Single-molecule fluorescence methods to study protein-RNA interactions underlying biomolecular condensates
LR Ganser, Y Ge, S Myong
Phase-Separated Biomolecular Condensates: Methods and Protocols, 149-160, 2022
32022
Linking folding dynamics and function of SAM/SAH riboswitches at the single molecule level
TW Liao, L Huang, TJ Wilson, LR Ganser, DMJ Lilley, T Ha
Nucleic acids research 51 (17), 8957-8969, 2023
22023
Publisher Correction: High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble
LR Ganser, J Lee, A Rangadurai, DK Merriman, ML Kelly, AD Kansal, ...
Nature structural & molecular biology 27 (6), 604, 2020
22020
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