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Jing Guo
Jing Guo
Research Scientist, MIT
Bestätigte E-Mail-Adresse bei mit.edu
Titel
Zitiert von
Zitiert von
Jahr
Unfolding and aggregation of monoclonal antibodies on cation exchange columns: effects of resin type, load buffer, and protein stability
J Guo, G Carta
Journal of Chromatography A 1388, 184-194, 2015
612015
Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part I. Chromatographic elution and batch adsorption behavior
J Guo, S Zhang, G Carta
Journal of Chromatography A 1356, 117-128, 2014
602014
Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part II. Protein structure effects by hydrogen deuterium exchange mass spectrometry
J Guo, G Carta
Journal of Chromatography A 1356, 129-137, 2014
492014
Surface induced three-peak elution behavior of a monoclonal antibody during cation exchange chromatography
J Guo, AD Creasy, G Barker, G Carta
Journal of Chromatography A 1474, 85-94, 2016
282016
Optimization of Single‐Column Batch and Multicolumn Continuous Protein A Chromatography and Performance Comparison Based on Mechanistic Model
J Guo, M Jin, D Kanani
Biotechnology Journal 15 (10), 2000192, 2020
162020
Host Cell Proteins During Biomanufacturing
JY Baik, J Guo, KH Lee
Cell Culture Engineering: Recombinant Protein Production, 295-311, 2019
82019
Mechanisms of precipitate formation during the purification of an Fc‐fusion protein
DG Greene, SJ Traylor, J Guo, LH Choe, S Modla, X Xu, N Singh, LL Lock, ...
Biotechnology and bioengineering 115 (10), 2489-2503, 2018
52018
Effect of solution condition on the binding behaviors of monoclonal antibody and fusion protein therapeutics in Protein A chromatography
J Guo, S Noyes, W Jin, H Curtis, X Xu, S Ghose
Journal of Chromatography A 1686, 463652, 2022
42022
Engineering protein A ligands to mitigate antibody loss during high-pH washes in protein A chromatography
S Bhoyar, M Foster, YH Oh, X Xu, SJ Traylor, J Guo, S Ghose, AM Lenhoff
Journal of Chromatography A 1696, 463962, 2023
22023
Predictive mechanistic modeling of loading and elution in protein A chromatography
S Bhoyar, V Kumar, M Foster, X Xu, SJ Traylor, J Guo, AM Lenhoff
Journal of Chromatography A 1713, 464558, 2024
12024
Conformational changes of biomolecules in ion-exchange chromatography
J Guo, X Xu
Ion-Exchange Chromatography and Related Techniques, 521-534, 2024
2024
Model-Based Design of Experiments for Antibody Glycosylation in CHO Cell Culture
J Guo, Y Ma, RD Braatz
2023 AIChE Annual Meeting, 2023
2023
Manufacturing scalability of isoelectric impurity precipitation during viral inactivation neutralization
S Traylor, W Jin, H Hua, J Guo, J Lee, X Xu, A Lenhoff, S Ghose
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
Optimization of batch and continuous multi-column protein A chromatography with mechanistic model and experiments
J Guo, S Zhang, D Kanani, M Jin
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
Antibody aggregation and unfolding on cation exchange chromatography media
J Guo, EJ Fernandez, JP O'Connell, G Carta
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014
2014
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