The role of the paracrine/autocrine mediator endothelin‐1 in regulation of cardiac contractility and growth FM Drawnel, CR Archer, HL Roderick British journal of pharmacology 168 (2), 296-317, 2013 | 116 | 2013 |
Characterization and validation of a human 3D cardiac microtissue for the assessment of changes in cardiac pathology CR Archer, R Sargeant, J Basak, J Pilling, JR Barnes, A Pointon Scientific reports 8 (1), 10160, 2018 | 105 | 2018 |
Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription downstream of endothelin type A receptors CR Archer, EL Robinson, FM Drawnel, HL Roderick Cellular signalling 36, 240-254, 2017 | 76 | 2017 |
From the cover: high-throughput imaging of cardiac microtissues for the assessment of cardiac contraction during drug discovery A Pointon, J Pilling, T Dorval, Y Wang, C Archer, C Pollard Toxicological Sciences 155 (2), 444-457, 2017 | 72 | 2017 |
Increasing the performance of pooled CRISPR–Cas9 drop-out screening BCS Cross, S Lawo, CR Archer, JR Hunt, JL Yarker, A Riccombeni, ... Scientific reports 6 (1), 31782, 2016 | 43 | 2016 |
MSK-mediated phosphorylation of histone H3 Ser28 couples MAPK signalling with early gene induction and cardiac hypertrophy EL Robinson, FM Drawnel, S Mehdi, CR Archer, W Liu, H Okkenhaug, ... Cells 11 (4), 604, 2022 | 9 | 2022 |
MSK phosphorylation of H3S28 is required for immediate early gene induction and cardiac hypertrophy EL Robinson, FM Drawnel, S Mehdi, CR Archer, W Liu, H Okkenhaug, ... bioRxiv, 2020.07. 28.224832, 2020 | 2 | 2020 |
Validation and utility of iPS-derived vascular smooth muscle cells as an in vitro vascular model for cardiovascular safety assessment CR Archer, M Budnik-Zawilska, A Pointon, K Gray Toxicology Letters 295, S109, 2018 | | 2018 |
Development and application of cardiac microtissues to cardiovascular safety C Archer, J Basak, R Sargeant, J Pilling, Y Wang, J Barnes, A Pointon Journal of Pharmacological and Toxicological Methods 93, 167-167, 2018 | | 2018 |
Genetic screening with CRISPR-Cas9: Proof & Principles BCS Cross, S Lawo, TME Scales, C Archer, J Hunt, A Riccombeni, ... | | 2018 |
Utilising FRAP to Assess Cx-43 Uncoupling in Spontaneously-beating Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPS-CMs) C Archer, A Pointon Journal of Pharmacological and Toxicological Methods 88, 235-236, 2017 | | 2017 |
Use of non-invasive reflective biomarkers to monitor 3D cardiac microtissue viability and toxicity J Basak, J Barnes, A Pointon, C Archer Toxicology Letters 280, S160, 2017 | | 2017 |
Abstract B163: Genetic screening with CRISPR-Cas9: Proof and principles BCS Cross, S Lawo, TME Scales, C Archer, J Hunt, A Riccombeni, ... Molecular Cancer Therapeutics 14 (12_Supplement_2), B163-B163, 2015 | | 2015 |
Interactions between GPCR-and growth factor-activated signalling pathways in the induction of cardiac hypertrophy C Archer | | 2013 |
Signalling requirements for ET-1-induced hypertrophy CR Archer, MD Bootman, HL Roderick Cardiovascular Research 93, S55-S55, 2012 | | 2012 |