Thomas Hale Segall-Shapiro
Thomas Hale Segall-Shapiro
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Creation of a bacterial cell controlled by a chemically synthesized genome
DG Gibson, JI Glass, C Lartigue, VN Noskov, RY Chuang, MA Algire, ...
science 329 (5987), 52-56, 2010
Modular control of multiple pathways using engineered orthogonal T7 polymerases
K Temme, R Hill, TH Segall-Shapiro, F Moser, CA Voigt
Nucleic Acids Research, 2012
Design of orthogonal genetic switches based on a crosstalk map of σs, anti‐σs, and promoters
VA Rhodius, TH Segall‐Shapiro, BD Sharon, A Ghodasara, E Orlova, ...
Molecular systems biology 9 (1), 702, 2013
A ‘resource allocator’for transcription based on a highly fragmented T7 RNA polymerase
TH Segall‐Shapiro, AJ Meyer, AD Ellington, ED Sontag, CA Voigt
Molecular systems biology 10 (7), 742, 2014
Advances in genetic circuit design: novel biochemistries, deep part mining, and precision gene expression
AAK Nielsen, TH Segall-Shapiro, CA Voigt
Current opinion in chemical biology 17 (6), 878-892, 2013
Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors
AJ Meyer, TH Segall-Shapiro, E Glassey, J Zhang, CA Voigt
Nature chemical biology 15 (2), 196-204, 2019
Engineered promoters enable constant gene expression at any copy number in bacteria
TH Segall-Shapiro, ED Sontag, CA Voigt
Nature biotechnology 36 (4), 352, 2018
An adaptor from translational to transcriptional control enables predictable assembly of complex regulation
CC Liu, L Qi, JB Lucks, TH Segall-Shapiro, D Wang, VK Mutalik, AP Arkin
Nature Methods, 2012
Tandem repeat coupled with endonuclease cleavage (TREC): a seamless modification tool for genome engineering in yeast
VN Noskov, TH Segall-Shapiro, RY Chuang
Nucleic acids research 38 (8), 2570-2576, 2010
Mesophilic and hyperthermophilic adenylate kinases differ in their tolerance to random fragmentation
TH Segall-Shapiro, PQ Nguyen, ED Dos Santos, S Subedi, J Judd, J Suh, ...
Journal of molecular biology 406 (1), 135-148, 2011
A genetically encoded and gate for cell-targeted metabolic labeling of proteins
A Mahdavi, TH Segall-Shapiro, S Kou, GA Jindal, KG Hoff, S Liu, ...
Journal of the American Chemical Society 135 (8), 2979-2982, 2013
TREC-IN: gene knock-in genetic tool for genomes cloned in yeast
S Chandran, VN Noskov, TH Segall-Shapiro, L Ma, C Whiteis, C Lartigue, ...
BMC genomics 15 (1), 1180, 2014
The structure of a thermophilic kinase shapes fitness upon random circular permutation
AM Jones, MM Mehta, EE Thomas, JT Atkinson, TH Segall-Shapiro, S Liu, ...
ACS synthetic biology 5 (5), 415-425, 2016
Designing a Modular Pathway for the Production of Engineered Chlorophyll
MH Carver, DA Sarkes, TH Segall-Shapiro, GO Ifere
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