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Jamie Schiffer
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Sea spray aerosol: where marine biology meets atmospheric chemistry
JM Schiffer, LE Mael, KA Prather, RE Amaro, VH Grassian
ACS central science 4 (12), 1617-1623, 2018
562018
Direct-to-biology accelerates PROTAC synthesis and the evaluation of linker effects on permeability and degradation
CE Hendrick, JR Jorgensen, C Chaudhry, II Strambeanu, JF Brazeau, ...
ACS medicinal chemistry letters 13 (7), 1182-1190, 2022
532022
Impacts of lipase enzyme on the surface properties of marine aerosols
JM Schiffer, M Luo, AC Dommer, G Thoron, M Pendergraft, MV Santander, ...
The Journal of Physical Chemistry Letters 9 (14), 3839-3849, 2018
292018
Improving the efficiency of ligand-binding protein design with molecular dynamics simulations
EP Barros, JM Schiffer, A Vorobieva, J Dou, D Baker, RE Amaro
Journal of chemical theory and computation 15 (10), 5703-5715, 2019
232019
Conformational communication mediates the reset step in t6A biosynthesis
A Luthra, N Paranagama, W Swinehart, S Bayooz, P Phan, V Quach, ...
Nucleic acids research 47 (12), 6551-6567, 2019
212019
Protein cofactors are essential for high-affinity DNA binding by the nuclear factor κB RelA subunit
MC Mulero, S Shahabi, MS Ko, JM Schiffer, DB Huang, VYF Wang, ...
Biochemistry 57 (20), 2943-2957, 2018
192018
Capturing invisible motions in the transition from ground to rare excited states of T4 lysozyme L99A
JM Schiffer, VA Feher, RD Malmstrom, R Sida, RE Amaro
Biophysical journal 111 (8), 1631-1640, 2016
182016
Microplastics outreach program: a systems-thinking approach to teach high school students about the chemistry and impacts of plastics
JM Schiffer, J Lyman, D Byrd, H Silverstein, MD Halls
Journal of Chemical Education 97 (1), 137-142, 2019
172019
Mechanisms for benzene dissociation through the excited state of T4 lysozyme L99A mutant
VA Feher, JM Schiffer, DJ Mermelstein, N Mih, LCT Pierce, ...
Biophysical journal 116 (2), 205-214, 2019
172019
How the ankyrin and SOCS box protein, ASB9, binds to creatine kinase
D Balasubramaniam, J Schiffer, J Parnell, SP Mir, RE Amaro, EA Komives
Biochemistry 54 (8), 1673-1680, 2015
172015
Model of the ankyrin and SOCS box protein, ASB9, E3 ligase reveals a mechanism for dynamic ubiquitin transfer
JM Schiffer, RD Malmstrom, J Parnell, C Ramirez-Sarmiento, J Reyes, ...
Structure 24 (8), 1248-1256, 2016
142016
Inhibitor potency varies widely among tumor-relevant human isocitrate dehydrogenase 1 mutants
D Avellaneda Matteo, GA Wells, LA Luna, AJ Grunseth, O Zagnitko, ...
Biochemical Journal 475 (20), 3221-3238, 2018
122018
Surfactant charge modulates structure and stability of lipase-embedded monolayers at marine-relevant aerosol surfaces
M Luo, AC Dommer, JM Schiffer, DJ Rez, AR Mitchell, RE Amaro, ...
Langmuir 35 (27), 9050-9060, 2019
112019
An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity
LA Luna, Z Lesecq, KA White, A Hoang, DA Scott, O Zagnitko, AA Bobkov, ...
Biochemical journal 477 (16), 2999-3018, 2020
92020
Factors controlling the transfer of biogenic organic species from seawater to sea spray aerosol
MV Santander, JM Schiffer, C Lee, JL Axson, MJ Tauber, KA Prather
Scientific reports 12 (1), 3580, 2022
82022
Cation-driven lipopolysaccharide morphological changes impact heterogeneous reactions of nitric acid with sea spray aerosol particles
C Lee, AC Dommer, JM Schiffer, RE Amaro, VH Grassian, KA Prather
The Journal of Physical Chemistry Letters 12 (20), 5023-5029, 2021
82021
Breaking the Glass Ceiling in Simulation and Modeling: Women in Pharmaceutical Discovery: Miniperspective
KL Damm-Ganamet, RL DesJarlais, T Marrone, AY Shih, JM Schiffer, ...
Journal of Medicinal Chemistry 63 (5), 1929-1936, 2020
42020
Water networks and correlated motions in mutant isocitrate dehydrogenase 1 (IDH1) are critical for allosteric inhibitor binding and activity
JM Chambers, W Miller, G Quichocho, V Upadhye, DA Matteo, AA Bobkov, ...
Biochemistry 59 (4), 479-490, 2019
32019
Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms
C Sohl, M Mealka, N Sierra, D Matteo, E Albekioni, R Khoury, T Mai, ...
2024
Monoacylglycerol lipase modulators
MK Ameriks, BN Laforteza, S Ravula, JM Schiffer, BM Stenne
US Patent 11,891,387, 2024
2024
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