Efficacy and safety of the RTS, S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 African sites RTS, S Clinical Trials Partnership (2014) PLoS medicine 11 (7), e1001685, 2014 | 343 | 2014 |
A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa E Wilkinson, M Giovanetti, H Tegally, JE San, R Lessells, D Cuadros, ... Science 374 (6566), 423-431, 2021 | 187 | 2021 |
Assessment of the novel T-cell activation marker–tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept study D Portevin, F Moukambi, P Clowes, A Bauer, M Chachage, NE Ntinginya, ... The Lancet infectious diseases 14 (10), 931-938, 2014 | 161 | 2014 |
Safety, immunogenicity, and protective efficacy against controlled human malaria infection of Plasmodium falciparum sporozoite vaccine in Tanzanian adults SA Jongo, SA Shekalaghe, LWP Church, AJ Ruben, T Schindler, ... The American journal of tropical medicine and hygiene 99 (2), 338, 2018 | 137 | 2018 |
Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites S Shekalaghe, M Rutaihwa, PF Billingsley, M Chemba, CA Daubenberger, ... The American journal of tropical medicine and hygiene 91 (3), 471, 2014 | 134 | 2014 |
Concentration and avidity of antibodies to different circumsporozoite epitopes correlate with RTS, S/AS01E malaria vaccine efficacy C Dobaño, H Sanz, H Sorgho, D Dosoo, M Mpina, I Ubillos, R Aguilar, ... Nature communications 10 (1), 2174, 2019 | 119 | 2019 |
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance H Tegally, JE San, M Cotten, M Moir, B Tegomoh, G Mboowa, DP Martin, ... Science 378 (6615), eabq5358, 2022 | 89 | 2022 |
Virosome-Formulated Plasmodium falciparum AMA-1 & CSP Derived Peptides as Malaria Vaccine: Randomized Phase 1b Trial in Semi-Immune Adults & Children PG Cech, T Aebi, MS Abdallah, M Mpina, EB Machunda, N Westerfeld, ... PloS one 6 (7), e22273, 2011 | 76 | 2011 |
Safety and differential antibody and T-cell responses to the Plasmodium falciparum sporozoite malaria vaccine, PfSPZ vaccine, by age in Tanzanian adults, adolescents, children … SA Jongo, LWP Church, AT Mtoro, S Chakravarty, AJ Ruben, ... The American journal of tropical medicine and hygiene 100 (6), 1433, 2019 | 71 | 2019 |
Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS, S/AS01E vaccination in African children I Ubillos, A Ayestaran, AJ Nhabomba, D Dosoo, M Vidal, A Jiménez, ... BMC medicine 16, 1-18, 2018 | 71 | 2018 |
Immune system development varies according to age, location, and anemia in African children DL Hill, EJ Carr, T Rutishauser, G Moncunill, JJ Campo, S Innocentin, ... Science translational medicine 12 (529), eaaw9522, 2020 | 63 | 2020 |
Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial M Oneko, LC Steinhardt, R Yego, RE Wiegand, PA Swanson, N Kc, ... Nature Medicine 27 (9), 1636-1645, 2021 | 57 | 2021 |
Controlled human malaria infection leads to long-lasting changes in innate and innate-like lymphocyte populations M Mpina, NJ Maurice, M Yajima, CK Slichter, HW Miller, M Dutta, ... The Journal of Immunology 199 (1), 107-118, 2017 | 54 | 2017 |
Increase of dose associated with decrease in protection against controlled human malaria infection by PfSPZ Vaccine in Tanzanian adults SA Jongo, LWP Church, AT Mtoro, T Schindler, S Chakravarty, AJ Ruben, ... Clinical Infectious Diseases 71 (11), 2849-2857, 2020 | 52 | 2020 |
Immunogenicity and protective efficacy of radiation-attenuated and chemo-attenuated PfSPZ vaccines in Equatoguinean adults SA Jongo, V Urbano, LWP Church, A Olotu, SR Manock, T Schindler, ... The American journal of tropical medicine and hygiene 104 (1), 283, 2021 | 51 | 2021 |
Experience and challenges from clinical trials with malaria vaccines in Africa G Mwangoka, B Ogutu, B Msambichaka, T Mzee, N Salim, S Kafuruki, ... Malaria journal 12, 1-9, 2013 | 46 | 2013 |
Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania P Amelio, D Portevin, K Reither, F Mhimbira, M Mpina, A Tumbo, B Nickel, ... PLoS neglected tropical diseases 11 (7), e0005817, 2017 | 44 | 2017 |
Molecular monitoring of the diversity of human pathogenic malaria species in blood donations on Bioko Island, Equatorial Guinea T Schindler, T Robaina, J Sax, JR Bieri, M Mpina, L Gondwe, L Acuche, ... Malaria journal 18, 1-11, 2019 | 43 | 2019 |
Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection JM Obiero, S Shekalaghe, CC Hermsen, M Mpina, EM Bijker, ... Infection and immunity 83 (5), 2185-2196, 2015 | 41 | 2015 |
CD36 deficiency protects against malarial anaemia in children by reducing Plasmodium falciparum‐infected red blood cell adherence to vascular endothelium J Chilongola, S Balthazary, M Mpina, M Mhando, E Mbugi Tropical Medicine & International Health 14 (7), 810-816, 2009 | 41 | 2009 |