Altered protein prenylation in Sertoli cells is associated with adult infertility resulting from childhood mumps infection XX Wang, P Ying, F Diao, Q Wang, D Ye, C Jiang, N Shen, N Xu, ... Journal of Experimental Medicine 210 (8), 1559-1574, 2013 | 76 | 2013 |
Protein prenylation and human diseases: a balance of protein farnesylation and geranylgeranylation N Xu, N Shen, XX Wang, S Jiang, B Xue, CJ Li Science China Life Sciences 58, 328-335, 2015 | 74 | 2015 |
The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb–mTORC1 signalling and leads to chronic heart failure N Xu, S Guan, Z Chen, Y Yu, J Xie, FY Pan, NW Zhao, L Liu, ZZ Yang, ... The Journal of pathology 235 (5), 672-685, 2015 | 48 | 2015 |
Deficiency of circulating monocytes ameliorates the progression of myxomatous valve degeneration in Marfan syndrome AJ Kim, N Xu, K Umeyama, A Hulin, SR Ponny, RJ Vagnozzi, EA Green, ... Circulation 141 (2), 132-146, 2020 | 40 | 2020 |
Macrophage lineages in heart valve development and disease AJ Kim, N Xu, KE Yutzey Cardiovascular Research 117 (3), 663-673, 2021 | 38 | 2021 |
Lipid-induced muscle insulin resistance is mediated by GGPPS via modulation of the RhoA/Rho kinase signaling pathway W Tao, J Wu, BX Xie, YY Zhao, N Shen, S Jiang, XX Wang, N Xu, C Jiang, ... Journal of Biological Chemistry 290 (33), 20086-20097, 2015 | 37 | 2015 |
GGPP-mediated protein geranylgeranylation in oocyte is essential for the establishment of oocyte-granulosa cell communication and primary-secondary follicle transition in mouse … C Jiang, F Diao, YJ Sang, N Xu, RL Zhu, XX Wang, Z Chen, WW Tao, ... PLoS genetics 13 (1), e1006535, 2017 | 34 | 2017 |
Hypoxia stabilizes microtubule networks and decreases tumor cell chemosensitivity to anticancer drugs through Egr‐1 WX Peng, FY Pan, XJ Liu, S Ning, N Xu, FL Meng, YQ Wang, CJ Li The Anatomical Record: Advances in Integrative Anatomy and Evolutionary …, 2010 | 29 | 2010 |
β-catenin signaling involves HGF-enhanced HepG2 scattering through activating MMP-7 transcription FY Pan, SZ Zhang, N Xu, FL Meng, HX Zhang, B Xue, X Han, CJ Li Histochemistry and cell biology 134, 285-295, 2010 | 28 | 2010 |
The constitutive activation of Egr-1/C/EBPa mediates the development of type 2 diabetes mellitus by enhancing hepatic gluconeogenesis N Shen, S Jiang, JM Lu, X Yu, SS Lai, JZ Zhang, JL Zhang, WW Tao, ... The American journal of pathology 185 (2), 513-523, 2015 | 26 | 2015 |
Ube2v1 positively regulates protein aggregation by modulating ubiquitin proteasome system performance partially through K63 ubiquitination N Xu, J Gulick, H Osinska, Y Yu, PM McLendon, K Shay-Winkler, ... Circulation research 126 (7), 907-922, 2020 | 24 | 2020 |
Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming D Chong, Y Gu, T Zhang, Y Xu, D Bu, Z Chen, N Xu, L Li, X Zhu, H Wang, ... Cell Discovery 8 (1), 106, 2022 | 19 | 2022 |
An unbiased high-throughput screen to identify novel effectors that impact on cardiomyocyte aggregate levels PM McLendon, G Davis, J Gulick, SR Singh, N Xu, N Salomonis, ... Circulation research 121 (6), 604-616, 2017 | 16 | 2017 |
Inhibition of Mutant αB Crystallin‐Induced Protein Aggregation by a Molecular Tweezer N Xu, G Bitan, T Schrader, FG Klärner, H Osinska, J Robbins Journal of the American Heart Association 6 (8), e006182, 2017 | 16 | 2017 |
Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart Z Chen, N Xu, D Chong, S Guan, C Jiang, Z Yang, C Li Cardiovascular research 114 (7), 965-978, 2018 | 15 | 2018 |
MMI‐0100 inhibits cardiac fibrosis in a mouse model overexpressing cardiac myosin binding protein C Q Meng, B Bhandary, H Osinska, J James, N Xu, K Shay‐Winkler, J Gulick, ... Journal of the American Heart Association 6 (9), e006590, 2017 | 15 | 2017 |
MILI, a PIWI family protein, inhibits melanoma cell migration through methylation of LINE1 X Wang, C Jiang, B Fu, R Zhu, F Diao, N Xu, Z Chen, W Tao, CJ Li Biochemical and biophysical research communications 457 (4), 514-519, 2015 | 15 | 2015 |
Therapeutic CCR2 blockade prevents inflammation and alleviates myxomatous valve disease in Marfan syndrome N Xu, KE Yutzey Basic to Translational Science 7 (11), 1143-1157, 2022 | 10 | 2022 |
Geranylgeranyl pyrophosphate-mediated protein geranylgeranylation regulates endothelial cell proliferation and apoptosis during vasculogenesis in mouse embryo D Chong, Z Chen, S Guan, T Zhang, N Xu, Y Zhao, C Li Journal of Genetics and Genomics 48 (4), 300-311, 2021 | 5 | 2021 |
Wnt Signaling Inhibition Prevents Postnatal Inflammation and Disease Progression in Mouse Congenital Myxomatous Valve Disease N Xu, CM Alfieri, Y Yu, M Guo, KE Yutzey Arteriosclerosis, Thrombosis, and Vascular Biology, 2024 | | 2024 |