| A novel retinoblastoma therapy from genomic and epigenetic analyses J Zhang, CA Benavente, J McEvoy, J Flores-Otero, L Ding, X Chen, ... Nature 481 (7381), 329-334, 2012 | 556 | 2012 |
| Genome stability is ensured by temporal control of kinetochore–microtubule dynamics SF Bakhoum, SL Thompson, AL Manning, DA Compton Nature cell biology 11 (1), 27-35, 2009 | 508 | 2009 |
| A conserved mechanism for Bni1-and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin JB Moseley, I Sagot, AL Manning, Y Xu, MJ Eck, D Pellman, BL Goode Molecular biology of the cell 15 (2), 896-907, 2004 | 337 | 2004 |
| Loss of pRB causes centromere dysfunction and chromosomal instability AL Manning, MS Longworth, NJ Dyson Genes & development 24 (13), 1364-1376, 2010 | 276 | 2010 |
| The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells AL Manning, NJ Ganem, SF Bakhoum, M Wagenbach, L Wordeman, ... Molecular biology of the cell 18 (8), 2970-2979, 2007 | 258 | 2007 |
| KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors JC Black, AL Manning, C Van Rechem, J Kim, B Ladd, J Cho, CM Pineda, ... Cell 154 (3), 541-555, 2013 | 237 | 2013 |
| CRL4Cdt2-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase RC Centore, CG Havens, AL Manning, JM Li, RL Flynn, A Tse, J Jin, ... Molecular cell 40 (1), 22-33, 2010 | 233 | 2010 |
| Negative regulation of yeast WASp by two SH3 domain-containing proteins AA Rodal, AL Manning, BL Goode, DG Drubin Current biology 13 (12), 1000-1008, 2003 | 184 | 2003 |
| Whole-genome doubling confers unique genetic vulnerabilities on tumour cells RJ Quinton, A DiDomizio, MA Vittoria, K Kotýnková, CJ Ticas, S Patel, ... Nature 590 (7846), 492-497, 2021 | 170 | 2021 |
| RB: mitotic implications of a tumour suppressor AL Manning, NJ Dyson Nature Reviews Cancer 12 (3), 220-226, 2012 | 163 | 2012 |
| H4K20 methylation regulates quiescence and chromatin compaction AG Evertts, AL Manning, X Wang, NJ Dyson, BA Garcia, HA Coller Molecular biology of the cell 24 (19), 3025-3037, 2013 | 155 | 2013 |
| CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore‐microtubule dynamics to promote mitotic progression and fidelity AL Manning, SF Bakhoum, S Maffini, C Correia‐Melo, H Maiato, ... The EMBO journal 29 (20), 3531-3543, 2010 | 140 | 2010 |
| Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux S Maffini, ARR Maia, AL Manning, Z Maliga, AL Pereira, M Junqueira, ... Current Biology 19 (18), 1566-1572, 2009 | 135 | 2009 |
| pRB, a tumor suppressor with a stabilizing presence AL Manning, NJ Dyson Trends in cell biology 21 (8), 433-441, 2011 | 107 | 2011 |
| Suppression of genome instability in pRB-deficient cells by enhancement of chromosome cohesion AL Manning, SA Yazinski, B Nicolay, A Bryll, L Zou, NJ Dyson Molecular cell 53 (6), 993-1004, 2014 | 93 | 2014 |
| Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation BN Nicolay, PS Danielian, F Kottakis, JD Lapek, I Sanidas, WO Miles, ... Genes & development 29 (17), 1875-1889, 2015 | 90 | 2015 |
| Structural and regulatory roles of nonmotor spindle proteins AL Manning, DA Compton Current opinion in cell biology 20 (1), 101-106, 2008 | 70 | 2008 |
| Identification of the kinase STK25 as an upstream activator of LATS signaling S Lim, N Hermance, T Mudianto, HM Mustaly, IPM Mauricio, MA Vittoria, ... Nature communications 10 (1), 1547, 2019 | 62 | 2019 |
| Mechanisms of spindle-pole organization are influenced by kinetochore activity in mammalian cells AL Manning, DA Compton Current biology 17 (3), 260-265, 2007 | 57 | 2007 |
| Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation AL Manning, C Benes, NJ Dyson Oncogene 33 (19), 2487-2494, 2014 | 50 | 2014 |
