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John R Lukens
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Cognate memory CD4+ T cells generated with dendritic cell priming influence the expansion, trafficking, and differentiation of secondary CD8+ T cells and enhance tumor control
ML Hwang, JR Lukens, TNJ Bullock
The Journal of Immunology 179 (9), 5829-5838, 2007
7292007
CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature
A Louveau, J Herz, MN Alme, AF Salvador, MQ Dong, KE Viar, SG Herod, ...
Nature neuroscience 21 (10), 1380-1391, 2018
6902018
NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens
PK Anand, RKS Malireddi, JR Lukens, P Vogel, J Bertin, M Lamkanfi, ...
Nature 488 (7411), 389-393, 2012
4302012
Mitochondria: diversity in the regulation of the NLRP3 inflammasome
P Gurung, JR Lukens, TD Kanneganti
Trends in molecular medicine 21 (3), 193-201, 2015
3752015
Dealing with danger in the CNS: the response of the immune system to injury
SP Gadani, JT Walsh, JR Lukens, J Kipnis
Neuron 87 (1), 47-62, 2015
3102015
Dietary modulation of the microbiome affects autoinflammatory disease
JR Lukens, P Gurung, P Vogel, GR Johnson, RA Carter, DJ McGoldrick, ...
Nature 516 (7530), 246-249, 2014
2972014
Emerging roles for the immune system in traumatic brain injury
CA McKee, JR Lukens
Frontiers in immunology 7, 231380, 2016
2472016
MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4
JT Walsh, S Hendrix, F Boato, I Smirnov, J Zheng, JR Lukens, S Gadani, ...
The Journal of clinical investigation 125 (2), 699-714, 2015
2142015
IL-1 family cytokines trigger sterile inflammatory disease
JR Lukens, JM Gross, TD Kanneganti
Frontiers in immunology 3, 33180, 2012
2102012
Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis
AC Bolte, AB Dutta, ME Hurt, I Smirnov, MA Kovacs, CA McKee, ...
Nature communications 11 (1), 4524, 2020
2092020
RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3
JR Lukens, P Vogel, GR Johnson, MA Kelliher, Y Iwakura, M Lamkanfi, ...
Nature 498 (7453), 224-227, 2013
1732013
Protective roles for caspase-8 and cFLIP in adult homeostasis
R Weinlich, A Oberst, CP Dillon, LJ Janke, S Milasta, JR Lukens, ...
Cell reports 5 (2), 340-348, 2013
1652013
Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis
PJ Shaw, JR Lukens, S Burns, H Chi, MA McGargill, TD Kanneganti
The Journal of Immunology 184 (9), 4610-4614, 2010
1632010
AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment
CR Lammert, EL Frost, CE Bellinger, AC Bolte, CA McKee, ME Hurt, ...
Nature 580 (7805), 647-652, 2020
1482020
Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity
PJ Shaw, MJ Barr, JR Lukens, MA McGargill, H Chi, TW Mak, ...
Immunity 34 (1), 75-84, 2011
1432011
Innate immunity at the crossroads of healthy brain maturation and neurodevelopmental disorders
KE Zengeler, JR Lukens
Nature Reviews Immunology 21 (7), 454-468, 2021
1422021
Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4+ T cells and γδ T cells
JR Lukens, MJ Barr, DD Chaplin, H Chi, TD Kanneganti
The Journal of Immunology 188 (7), 3107-3115, 2012
1362012
Intrahepatic IL-10 maintains NKG2A+ Ly49− liver NK cells in a functionally hyporesponsive state
MG Lassen, JR Lukens, JS Dolina, MG Brown, YS Hahn
The Journal of Immunology 184 (5), 2693-2701, 2010
1332010
Critical role for inflammasome-independent IL-1β production in osteomyelitis
JR Lukens, JM Gross, C Calabrese, Y Iwakura, M Lamkanfi, P Vogel, ...
Proceedings of the National Academy of Sciences 111 (3), 1066-1071, 2014
1292014
The NLRP12 sensor negatively regulates autoinflammatory disease by modulating interleukin-4 production in T cells
JR Lukens, P Gurung, PJ Shaw, MJ Barr, MH Zaki, SA Brown, P Vogel, ...
Immunity 42 (4), 654-664, 2015
1152015
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Articles 1–20