Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease K Midwood, S Sacre, AM Piccinini, J Inglis, A Trebaul, E Chan, S Drexler, ... Nature medicine 15 (7), 774, 2009 | 758 | 2009 |
Dependence of cyclin E-CDK2 kinase activity on cell anchorage F Fang, G Orend, N Watanabe, T Hunter, E Ruoslahti Science 271 (5248), 499-502, 1996 | 510 | 1996 |
The role of tenascin-C in tissue injury and tumorigenesis KS Midwood, G Orend Journal of cell communication and signaling 3 (3-4), 287-310, 2009 | 471 | 2009 |
Tenascin-C induced signaling in cancer G Orend, R Chiquet-Ehrismann Cancer letters 244 (2), 143-163, 2006 | 424 | 2006 |
CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis P Baumann, N Cremers, F Kroese, G Orend, R Chiquet-Ehrismann, ... Cancer research 65 (23), 10783-10793, 2005 | 423 | 2005 |
Advances in tenascin-C biology KS Midwood, T Hussenet, B Langlois, G Orend Cellular and molecular life sciences 68 (19), 3175, 2011 | 356 | 2011 |
Tenascin-C at a glance KS Midwood, M Chiquet, RP Tucker, G Orend J Cell Sci 129 (23), 4321-4327, 2016 | 327 | 2016 |
Interference of tenascin-C with syndecan-4 binding to fibronectin blocks cell adhesion and stimulates tumor cell proliferation W Huang, R Chiquet-Ehrismann, JV Moyano, A Garcia-Pardo, G Orend Cancer research 61 (23), 8586-8594, 2001 | 318 | 2001 |
Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression S Bourdoulous, G Orend, DA MacKenna, R Pasqualini, E Ruoslahti The Journal of cell biology 143 (1), 267-276, 1998 | 296 | 1998 |
Tenascins in stem cell niches R Chiquet-Ehrismann, G Orend, M Chiquet, RP Tucker, KS Midwood Matrix Biology 37, 112-123, 2014 | 182 | 2014 |
Fibronectin and tenascin-C: accomplices in vascular morphogenesis during development and tumor growth E Van Obberghen-Schilling, RP Tucker, F Saupe, I Gasser, B Cseh, ... International Journal of Developmental Biology 55 (4-5), 511-525, 2011 | 159 | 2011 |
Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21Cip1 and p27Kip1 in anchorage-independent cells G Orend, T Hunter, E Ruoslahti Oncogene 16 (20), 2575, 1998 | 158 | 1998 |
Potential oncogenic action of tenascin-C in tumorigenesis G Orend The international journal of biochemistry & cell biology 37 (5), 1066-1083, 2005 | 149 | 2005 |
Differential gene expression analysis reveals activation of growth promoting signaling pathways by tenascin-C C Ruiz, W Huang, ME Hegi, K Lange, MF Hamou, E Fluri, EJ Oakeley, ... Cancer research 64 (20), 7377-7385, 2004 | 146 | 2004 |
Tenascin-C downregulates wnt inhibitor dickkopf-1, promoting tumorigenesis in a neuroendocrine tumor model F Saupe, A Schwenzer, Y Jia, I Gasser, C Spenlé, B Langlois, ... Cell reports 5 (2), 482-492, 2013 | 114 | 2013 |
RGD-independent cell adhesion via a tissue transglutaminase-fibronectin matrix promotes fibronectin fibril deposition and requires syndecan-4/2 and α5β1 integrin co-signaling Z Wang, RJ Collighan, SR Gross, EHJ Danen, G Orend, D Telci, M Griffin Journal of Biological Chemistry 285 (51), 40212-40229, 2010 | 107 | 2010 |
Role of laminins in physiological and pathological angiogenesis P Simon-Assmann, G Orend, E Mammadova-Bach, C Spenlé, O Lefebvre International journal of developmental biology 55 (4-5), 455-465, 2011 | 106 | 2011 |
Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation MM Edwards, E Mammadova-Bach, F Alpy, A Klein, WL Hicks, M Roux, ... Journal of Biological Chemistry 285 (10), 7697-7711, 2010 | 102 | 2010 |
Adhesion modulation by antiadhesive molecules of the extracellular matrix G Orend, R Chiquet-Ehrismann Experimental cell research 261 (1), 104-110, 2000 | 101 | 2000 |
Tenascin-C blocks cell-cycle progression of anchorage-dependent fibroblasts on fibronectin through inhibition of syndecan-4 G Orend, W Huang, MA Olayioye, NE Hynes, R Chiquet-Ehrismann Oncogene 22 (25), 3917, 2003 | 100 | 2003 |