Gertraud Orend
Gertraud Orend
Research director INSERM, University Strassbourg, France
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Zitiert von
Zitiert von
Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease
K Midwood, S Sacre, AM Piccinini, J Inglis, A Trebaul, E Chan, S Drexler, ...
Nature medicine 15 (7), 774, 2009
Dependence of cyclin E-CDK2 kinase activity on cell anchorage
F Fang, G Orend, N Watanabe, T Hunter, E Ruoslahti
Science 271 (5248), 499-502, 1996
The role of tenascin-C in tissue injury and tumorigenesis
KS Midwood, G Orend
Journal of cell communication and signaling 3 (3-4), 287-310, 2009
Tenascin-C induced signaling in cancer
G Orend, R Chiquet-Ehrismann
Cancer letters 244 (2), 143-163, 2006
CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis
P Baumann, N Cremers, F Kroese, G Orend, R Chiquet-Ehrismann, ...
Cancer research 65 (23), 10783-10793, 2005
Advances in tenascin-C biology
KS Midwood, T Hussenet, B Langlois, G Orend
Cellular and molecular life sciences 68 (19), 3175, 2011
Tenascin-C at a glance
KS Midwood, M Chiquet, RP Tucker, G Orend
J Cell Sci 129 (23), 4321-4327, 2016
Interference of tenascin-C with syndecan-4 binding to fibronectin blocks cell adhesion and stimulates tumor cell proliferation
W Huang, R Chiquet-Ehrismann, JV Moyano, A Garcia-Pardo, G Orend
Cancer research 61 (23), 8586-8594, 2001
Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression
S Bourdoulous, G Orend, DA MacKenna, R Pasqualini, E Ruoslahti
The Journal of cell biology 143 (1), 267-276, 1998
Tenascins in stem cell niches
R Chiquet-Ehrismann, G Orend, M Chiquet, RP Tucker, KS Midwood
Matrix Biology 37, 112-123, 2014
Fibronectin and tenascin-C: accomplices in vascular morphogenesis during development and tumor growth
E Van Obberghen-Schilling, RP Tucker, F Saupe, I Gasser, B Cseh, ...
International Journal of Developmental Biology 55 (4-5), 511-525, 2011
Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21Cip1 and p27Kip1 in anchorage-independent cells
G Orend, T Hunter, E Ruoslahti
Oncogene 16 (20), 2575, 1998
Potential oncogenic action of tenascin-C in tumorigenesis
G Orend
The international journal of biochemistry & cell biology 37 (5), 1066-1083, 2005
Differential gene expression analysis reveals activation of growth promoting signaling pathways by tenascin-C
C Ruiz, W Huang, ME Hegi, K Lange, MF Hamou, E Fluri, EJ Oakeley, ...
Cancer research 64 (20), 7377-7385, 2004
Tenascin-C downregulates wnt inhibitor dickkopf-1, promoting tumorigenesis in a neuroendocrine tumor model
F Saupe, A Schwenzer, Y Jia, I Gasser, C Spenlé, B Langlois, ...
Cell reports 5 (2), 482-492, 2013
RGD-independent cell adhesion via a tissue transglutaminase-fibronectin matrix promotes fibronectin fibril deposition and requires syndecan-4/2 and α5β1 integrin co-signaling
Z Wang, RJ Collighan, SR Gross, EHJ Danen, G Orend, D Telci, M Griffin
Journal of Biological Chemistry 285 (51), 40212-40229, 2010
Role of laminins in physiological and pathological angiogenesis
P Simon-Assmann, G Orend, E Mammadova-Bach, C Spenlé, O Lefebvre
International journal of developmental biology 55 (4-5), 455-465, 2011
Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation
MM Edwards, E Mammadova-Bach, F Alpy, A Klein, WL Hicks, M Roux, ...
Journal of Biological Chemistry 285 (10), 7697-7711, 2010
Adhesion modulation by antiadhesive molecules of the extracellular matrix
G Orend, R Chiquet-Ehrismann
Experimental cell research 261 (1), 104-110, 2000
Tenascin-C blocks cell-cycle progression of anchorage-dependent fibroblasts on fibronectin through inhibition of syndecan-4
G Orend, W Huang, MA Olayioye, NE Hynes, R Chiquet-Ehrismann
Oncogene 22 (25), 3917, 2003
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