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Lars Velten
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Human haematopoietic stem cell lineage commitment is a continuous process
L Velten, SF Haas, S Raffel, S Blaszkiewicz, S Islam, BP Hennig, C Hirche, ...
Nature cell biology 19 (4), 271-281, 2017
9382017
Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization
C Baccin, J Al-Sabah, L Velten, PM Helbling, F Grünschläger, ...
Nature cell biology 22 (1), 38-48, 2020
6102020
Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors
S Haas, J Hansson, D Klimmeck, D Loeffler, L Velten, H Uckelmann, ...
Cell stem cell 17 (4), 422-434, 2015
4332015
Deciphering the rules by which 5′-UTR sequences affect protein expression in yeast
S Dvir, L Velten, E Sharon, D Zeevi, LB Carey, A Weinberger, E Segal
Proceedings of the National Academy of Sciences 110 (30), E2792-E2801, 2013
2932013
Targeted Perturb-seq enables genome-scale genetic screens in single cells
D Schraivogel, AR Gschwind, JH Milbank, DR Leonce, P Jakob, L Mathur, ...
Nature methods 17 (6), 629-635, 2020
1562020
Large-scale low-cost NGS library preparation using a robust Tn5 purification and tagmentation protocol
BP Hennig, L Velten, I Racke, CS Tu, M Thoms, V Rybin, H Besir, ...
G3: Genes, Genomes, Genetics 8 (1), 79-89, 2018
1382018
Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states
S Triana, D Vonficht, L Jopp-Saile, S Raffel, R Lutz, D Leonce, M Antes, ...
Nature immunology 22 (12), 1577-1589, 2021
1012021
Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging
K Young, E Eudy, R Bell, MA Loberg, T Stearns, D Sharma, L Velten, ...
Cell stem cell 28 (8), 1473-1482. e7, 2021
1012021
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics
L Velten, BA Story, P Hernández-Malmierca, S Raffel, DR Leonce, ...
Nature communications 12 (1), 1366, 2021
912021
Single‐cell polyadenylation site mapping reveals 3′ isoform choice variability
L Velten, S Anders, A Pekowska, AI Järvelin, W Huber, V Pelechano, ...
Molecular systems biology 11 (6), 812, 2015
692015
Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia
S Beneyto-Calabuig, AK Merbach, JA Kniffka, M Antes, C Szu-Tu, ...
Cell Stem Cell, 2023
252023
Decoding gene regulation in the mouse embryo using single-cell multi-omics
R Argelaguet, T Lohoff, JG Li, A Nakhuda, D Drage, F Krueger, L Velten, ...
BioRxiv, 2022.06. 15.496239, 2022
252022
scTAM-seq enables targeted high-confidence analysis of DNA methylation in single cells
A Bianchi, M Scherer, R Zaurin, K Quililan, L Velten, R Beekman
Genome Biology 23 (1), 229, 2022
152022
Transcriptomic diversity in human medullary thymic epithelial cells
JA Carter, L Strömich, M Peacey, SR Chapin, L Velten, LM Steinmetz, ...
Nature Communications 13 (1), 4296, 2022
152022
Single‐cell RNA sequencing of motoneurons identifies regulators of synaptic wiring in Drosophila embryos
J Velten, X Gao, P Van Nierop y Sanchez, K Domsch, R Agarwal, ...
Molecular Systems Biology 18 (3), e10255, 2022
8*2022
Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis
AV Kurtova, M Heinlein, S Haas, L Velten, GJP Dijkgraaf, EE Storm, ...
Blood Advances 7 (4), 491-507, 2023
42023
Integrative single‐cell expression and functional studies unravels a sensitization to cytarabine‐based chemotherapy through HIF pathway inhibition in AML leukemia stem cells
T Velasco‐Hernandez, JL Trincado, M Vinyoles, A Closa, ...
HemaSphere 8 (2), e45, 2024
12024
Single-cell division tracing and transcriptomics reveal cell types and differentiation paths in the regenerating lung
LR Martins, L Sieverling, M Michelhans, C Schiller, C Erkut, ...
Nature Communications 15 (1), 2246, 2024
2024
Biological basis of extensive pleiotropy between blood traits and cancer risk
MA Pardo-Cea, X Farré, A Esteve, J Palade, R Espín, F Mateo, E Alsop, ...
Genome Medicine 16 (1), 21, 2024
2024
Identifying cancer cells from calling single-nucleotide variants in scRNA-seq data
V Marot-Lassauzaie, S Beneyto-Calabuig, B Obermayer, L Velten, ...
bioRxiv, 2024.02. 21.581377, 2024
2024
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