| CRISPR/Cas9‐mediated genome engineering: an adeno‐associated viral (AAV) vector toolbox E Senís, C Fatouros, S Große, E Wiedtke, D Niopek, AK Mueller, K Börner, ... Biotechnology journal 9 (11), 1402-1412, 2014 | 349 | 2014 |
| Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells D Niopek, D Benzinger, J Roensch, T Draebing, P Wehler, R Eils, ... Nature communications 5 (1), 4404, 2014 | 265 | 2014 |
| Optogenetic control of nuclear protein export D Niopek, P Wehler, J Roensch, R Eils, B Di Ventura Nature communications 7 (1), 10624, 2016 | 240 | 2016 |
| Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9 F Bubeck, MD Hoffmann, Z Harteveld, S Aschenbrenner, A Bietz, ... Nature methods 15 (11), 924-927, 2018 | 205 | 2018 |
| Cell-specific CRISPR–Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins MD Hoffmann, S Aschenbrenner, S Grosse, K Rapti, C Domenger, ... Nucleic acids research 47 (13), e75-e75, 2019 | 97 | 2019 |
| Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines K Börner, D Niopek, G Cotugno, M Kaldenbach, T Pankert, J Willemsen, ... Nucleic acids research 41 (21), e199-e199, 2013 | 73 | 2013 |
| Coupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9 target specificity S Aschenbrenner, SM Kallenberger, MD Hoffmann, A Huck, R Eils, ... Science advances 6 (6), eaay0187, 2020 | 57 | 2020 |
| AAV vector-mediated in vivo reprogramming into pluripotency E Senís, L Mosteiro, S Wilkening, E Wiedtke, A Nowrouzi, S Afzal, ... Nature Communications 9 (1), 2651, 2018 | 54 | 2018 |
| Creating functional engineered variants of the single-module non-ribosomal peptide synthetase IndC by T domain exchange R Beer, K Herbst, N Ignatiadis, I Kats, L Adlung, H Meyer, D Niopek, ... Molecular BioSystems 10 (7), 1709-1718, 2014 | 48 | 2014 |
| Engineering and evolution of synthetic adeno-associated virus (AAV) gene therapy vectors via DNA family shuffling E Kienle, E Senís, K Börner, D Niopek, E Wiedtke, S Grosse, D Grimm JoVE (Journal of Visualized Experiments), e3819, 2012 | 48 | 2012 |
| A robust and all-inclusive pipeline for shuffling of adeno-associated viruses AK Herrmann, C Bender, E Kienle, S Grosse, J El Andari, J Botta, ... ACS synthetic biology 8 (1), 194-206, 2018 | 39 | 2018 |
| Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein MD Hoffmann, J Mathony, J Upmeier zu Belzen, Z Harteveld, ... Nucleic acids research 49 (5), e29-e29, 2021 | 34 | 2021 |
| Controlling cells with light and LOV MD Hoffmann, F Bubeck, R Eils, D Niopek Advanced Biosystems 2 (9), 1800098, 2018 | 31 | 2018 |
| Enlightening allostery: designing switchable proteins by photoreceptor fusion J Mathony, D Niopek Advanced Biology 5 (5), 2000181, 2021 | 25 | 2021 |
| Computational design of anti-CRISPR proteins with improved inhibition potency J Mathony, Z Harteveld, C Schmelas, J Upmeier zu Belzen, ... Nature chemical biology 16 (7), 725-730, 2020 | 23 | 2020 |
| Leveraging implicit knowledge in neural networks for functional dissection and engineering of proteins J Upmeier zu Belzen, T Bürgel, S Holderbach, F Bubeck, L Adam, ... Nature Machine Intelligence 1 (5), 225-235, 2019 | 21 | 2019 |
| Optogenetic control of nuclear protein import in living cells using light‐inducible nuclear localization signals (LINuS) P Wehler, D Niopek, R Eils, B Di Ventura Current protocols in chemical biology 8 (2), 131-145, 2016 | 18 | 2016 |
| Are artists and engineers inventing the culture of tomorrow? U Damm, B Hopfengärtner, D Niopek, P Bayer Futures 48, 55-64, 2013 | 16 | 2013 |
| Optogenetics and CRISPR: a new relationship built to last J Mathony, MD Hoffmann, D Niopek Photoswitching Proteins: Methods and Protocols, 261-281, 2020 | 13 | 2020 |
| A hepatic GAbp-AMPK axis links inflammatory signaling to systemic vascular damage K Niopek, BE Üstünel, S Seitz, M Sakurai, A Zota, F Mattijssen, X Wang, ... Cell reports 20 (6), 1422-1434, 2017 | 13 | 2017 |
Roland EilsProfessor for Digital Health, Charité-Universitätsmedizin Berlin and Berlin Institute of HealthBestätigte E-Mail-Adresse bei charite.de
