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Katja Witschas
Katja Witschas
Postdoctoral researcher, Gent University
Verified email at ugent.be
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Cited by
Cited by
Year
Cx43 hemichannel microdomain signaling at the intercalated disc enhances cardiac excitability.
MA De Smet, A Lissoni, T Nezlobinsky, N Wang, E Dries, ...
J Clin Invest. 2021 Feb 23:137752, 2021
612021
Comparing ion conductance recordings of synthetic lipid bilayers with cell membranes containing TRP channels
KR Laub, K Witschas, A Blicher, SB Madsen, A Lückhoff, T Heimburg
Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (5), 1123-1134, 2012
502012
RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes
A Lissoni, P Hulpiau, T Martins-Marques, N Wang, G Bultynck, R Schulz, ...
Cardiovascular Research 117 (1), 123-136, 2021
352021
A critical GxxxA motif in the γ6 calcium channel subunit mediates its inhibitory effect on Cav3.1 calcium current
Z Lin, K Witschas, T Garcia, RS Chen, JP Hansen, ZM Sellers, ...
The Journal of Physiology 586 (22), 5349-5366, 2008
312008
Structural modeling and patch-clamp analysis of pain-related mutation TRPA1-N855S reveal inter-subunit salt bridges stabilizing the channel open state
V Zíma, K Witschas, A Hynkova, L Zímová, I Barvík, V Vlachova
Neuropharmacology 93, 294-307, 2015
292015
Dampened activity of ryanodine receptor channels in mutant skeletal muscle lacking TRIC‐A
S El‐Ajouz, E Venturi, K Witschas, M Beech, AD Wilson, C Lindsay, ...
The Journal of Physiology 595 (14), 4769-4784, 2017
202017
Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform
E Venturi, C Lindsay, S Lotteau, Z Yang, E Steer, K Witschas, AD Wilson, ...
British Journal of Pharmacology 175 (6), 938-952, 2018
182018
Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8
FJP Kühn, K Witschas, C Kühn, A Lückhoff
Journal of biological chemistry 285 (35), 26806-26814, 2010
182010
Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments
L Leybaert, MAJ De Smet, A Lissoni, R Allewaert, HL Roderick, ...
The Journal of clinical investigation 133 (6), 2023
132023
Targeting gliovascular connexins prevents inflammatory blood-brain barrier leakage and astrogliosis
M De Bock, M De Smet, S Verwaerde, H Tahiri, S Schumacher, ...
Jci Insight 7 (16), 2022
132022
Enhanced activity of multiple TRIC‐B channels: an endoplasmic reticulum/sarcoplasmic reticulum mechanism to boost counterion currents
F O'Brien, D Eberhardt, K Witschas, S El‐Ajouz, T Iida, M Nishi, ...
The Journal of Physiology 597 (10), 2691-2705, 2019
112019
Interaction of a peptide derived from C-terminus of human TRPA1 channel with model membranes mimicking the inner leaflet of the plasma membrane
K Witschas, ML Jobin, DN Korkut, MM Vladan, G Salgado, S Lecomte, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (5), 1147-1156, 2015
112015
Gap19, a Cx43 Hemichannel Inhibitor, Acts as a Gating Modifier That Decreases Main State Opening While Increasing Substate Gating
A Lissoni, N Wang, T Nezlobinskii, M De Smet, AV Panfilov, ...
Int J Mol Sci. 21 (19), E7340, 2020
82020
Inhibiting astrocyte connexin‐43 hemichannels blocks radiation‐induced vesicular VEGF‐A release and blood–brain barrier dysfunction
S Schumacher, H Tahiri, P Ezan, N Rouach, K Witschas, L Leybaert
Glia, 2023
22023
Cx43 can form functional channels at the nuclear envelope and modulate gene expression in cardiac cells
T Martins-Marques, K Witschas, I Ribeiro, M Zuzarte, S Catarino, ...
Open Biology 13 (11), 230258, 2023
12023
Dampened Activity of Single Ryanodine Receptor Channels in Mice Devoid of TRIC-A
K Witschas, F O'Brien, E Venturi, S El-Ajouz, M Beech, D Eberhardt, T Iida, ...
Biophysical Journal 110 (3), 266a, 2016
12016
A TR (i) P Into Channel Gating-from Proteins to Lipids
K Witschas, A Lückhoff
Hochschulbibliothek der Rheinisch-Westfälischen Technischen Hochschule Aachen, 2012
12012
IP3RPEP6, a novel peptide inhibitor of IP3 receptor channels that does not affect connexin‐43 hemichannels
S Tao, P Hulpiau, LE Wagner, K Witschas, DI Yule, G Bultynck, L Leybaert
Acta Physiologica, e14086, 2024
2024
Cx43 Hemichannel and Panx1 Channel Modulation by Gap19 and 10Panx1 Peptides
A Lissoni, S Tao, R Allewaert, K Witschas, L Leybaert
International Journal of Molecular Sciences 24 (14), 11612, 2023
2023
Cooperative Gating Among Ion-Channel Species in Junctional Sarcoplasmic Reticulum
E Venturi, F O'Brien, D Eberhardt, K Witschas, S El-Ajouz, T Iida, ...
Biophysical Journal 116 (3), 521a, 2019
2019
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