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Jamie Kwasnieski
Jamie Kwasnieski
Dyno Therapeutics
Verified email at dynotx.com
Title
Cited by
Cited by
Year
Complex effects of nucleotide variants in a mammalian cis-regulatory element
JC Kwasnieski, I Mogno, CA Myers, JC Corbo, BA Cohen
Proceedings of the National Academy of Sciences 109 (47), 19498-19503, 2012
2792012
High-throughput functional testing of ENCODE segmentation predictions
JC Kwasnieski, C Fiore, HG Chaudhari, BA Cohen
Genome research 24 (10), 1595-1602, 2014
2692014
mRNA poly (A)-tail changes specified by deadenylation broadly reshape translation in Drosophila oocytes and early embryos
SW Eichhorn, AO Subtelny, I Kronja, JC Kwasnieski, TL Orr-Weaver, ...
Elife 5, e16955, 2016
1572016
Massively parallel synthetic promoter assays reveal the in vivo effects of binding site variants
I Mogno, JC Kwasnieski, BA Cohen
Genome research 23 (11), 1908-1915, 2013
1112013
A simple grammar defines activating and repressing cis-regulatory elements in photoreceptors
MA White, JC Kwasnieski, CA Myers, SQ Shen, JC Corbo, BA Cohen
Cell Reports 17 (5), 1247-1254, 2016
762016
Early genome activation in Drosophila is extensive with an initial tendency for aborted transcripts and retained introns
JC Kwasnieski, TL Orr-Weaver, DP Bartel
Genome research 29 (7), 1188-1197, 2019
602019
Overcoming immunological challenges limiting capsid-mediated gene therapy with machine learning
AZ Wec, KS Lin, JC Kwasnieski, S Sinai, J Gerold, ED Kelsic
Frontiers in Immunology 12, 674021, 2021
152021
Efficient design of optimized AAV capsids using multi-property machine learning models trained across cells, organs and species
S Abestesh, I Akartuna, A Brown, M Cramer, F Damani, J Gerold, J Gorns, ...
MOLECULAR THERAPY 29 (4), 12-12, 2021
12021
Determining Cell-Type Specific Distribution of AAV Variants in NHP Retina Using Single-Nuclei RNA Sequencing
A Ghosh, I Brenckle, S Wolock, C Sengel, S Lapan, JC Kwasnieski, ...
MOLECULAR THERAPY 30 (4), 440-440, 2022
2022
Machine-Guided Design Reveals AAV Variants Efficient in Transducing NHP Retina After Intravitreal Delivery
HT Turunen, M Cramer, J Gerold, H Kuchwara, JC Kwasnieski, S Lapan, ...
MOLECULAR THERAPY 30 (4), 555-555, 2022
2022
AAV Capsid Property Estimation Is Improved by Combining Single-Molecule ID Tags and Hierarchical Bayesian Modeling of Experimental Processes
K Lin, J Otwinowski, B Tobin, S Wolock, J Kwasnieski, C Sengel, R Ogurlu, ...
MOLECULAR THERAPY 29 (4), 98-98, 2021
2021
cis-Regulation in the Mammalian Rod Photoreceptor
JC Kwasnieski
Washington University in St. Louis, 2014
2014
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