WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy D Bakula, AJ Müller, T Zuleger, Z Takacs, M Franz-Wachtel, AK Thost, ... Nature communications 8 (1), 15637, 2017 | 186 | 2017 |
The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells P Gao, C Bauvy, S Souquere, G Tonelli, L Liu, Y Zhu, Z Qiao, D Bakula, ... Journal of Biological Chemistry 285 (33), 25570-25581, 2010 | 138 | 2010 |
MitophAging: mitophagy in aging and disease D Bakula, M Scheibye-Knudsen Frontiers in cell and developmental biology 8, 239, 2020 | 103 | 2020 |
Modulation of intracellular calcium homeostasis blocks autophagosome formation N Engedal, ML Torgersen, IJ Guldvik, SJ Barfeld, D Bakula, F Saetre, ... Autophagy 9 (10), 1475-1490, 2013 | 103 | 2013 |
Atg18 function in autophagy is regulated by specific sites within its β-propeller E Rieter, F Vinke, D Bakula, E Cebollero, C Ungermann, ... Journal of cell science 126 (2), 593-604, 2013 | 100 | 2013 |
Lipid droplet and early autophagosomal membrane targeting of Atg2A and Atg14L in human tumor cells [S] SG Pfisterer, D Bakula, T Frickey, A Cezanne, D Brigger, MP Tschan, ... Journal of lipid research 55 (7), 1267-1278, 2014 | 65 | 2014 |
Monogenic diseases of DNA repair G Keijzers, D Bakula, M Scheibye-Knudsen New England Journal of Medicine 377 (19), 1868-1876, 2017 | 62 | 2017 |
Nuclear morphology is a deep learning biomarker of cellular senescence I Heckenbach, GV Mkrtchyan, MB Ezra, D Bakula, JS Madsen, ... Nature Aging 2 (8), 742-755, 2022 | 57 | 2022 |
ARDD 2020: from aging mechanisms to interventions GV Mkrtchyan, K Abdelmohsen, P Andreux, I Bagdonaite, N Barzilai, ... Aging (Albany NY) 12 (24), 24484, 2020 | 54 | 2020 |
Human exonuclease 1 (EXO1) regulatory functions in DNA replication with putative roles in cancer G Keijzers, D Bakula, MA Petr, NGK Madsen, A Teklu, G Mkrtchyan, ... International journal of molecular sciences 20 (1), 74, 2018 | 50 | 2018 |
Defining regulatory and phosphoinositide-binding sites in the human WIPI-1 β-propeller responsible for autophagosomal membrane localization downstream of mTORC1 inhibition A Gaugel, D Bakula, A Hoffmann, T Proikas-Cezanne Journal of Molecular Signaling 7 (1), 1-17, 2012 | 28 | 2012 |
Clinical trials targeting aging JL Nielsen, D Bakula, M Scheibye-Knudsen Frontiers in aging 3, 820215, 2022 | 27 | 2022 |
Aging and drug discovery D Bakula, AM Aliper, P Mamoshina, MA Petr, A Teklu, JA Baur, J Campisi, ... Aging (Albany NY) 10 (11), 3079, 2018 | 25 | 2018 |
WIPI β-propellers function as scaffolds for STK11/LKB1-AMPK and AMPK-related kinase signaling in autophagy D Bakula, AJ Mueller, T Proikas-Cezanne Autophagy 14 (6), 1082-1083, 2018 | 24 | 2018 |
Latest advances in aging research and drug discovery D Bakula, A Ablasser, A Aguzzi, A Antebi, N Barzilai, MI Bittner, ... Aging (albany NY) 11 (22), 9971, 2019 | 18 | 2019 |
WIPI β-propellers in autophagy-related diseases and longevity D Bakula, Z Takacs, T Proikas-Cezanne Biochemical Society Transactions 41 (4), 962-967, 2013 | 16 | 2013 |
New methodologies in ageing research B Osborne, D Bakula, MB Ezra, C Dresen, E Hartmann, SM Kristensen, ... Ageing Research Reviews 62, 101094, 2020 | 11 | 2020 |
WIPI β-propellers at the crossroads of autophagosome and lipid droplet dynamics SG Pfisterer, D Bakula, A Cezanne, H Robenek, T Proikas-Cezanne Biochemical Society Transactions 42 (5), 1414-1417, 2014 | 10 | 2014 |
Vulnerability of frontal brain neurons for the toxicity of expanded ataxin-3 J Schmidt, AK Mayer, D Bakula, J Freude, JJ Weber, A Weiss, O Riess, ... Human Molecular Genetics 28 (9), 1463-1473, 2019 | 9 | 2019 |
Meeting report: Aging research and drug discovery E Meron, M Thaysen, S Angeli, A Antebi, N Barzilai, JA Baur, ... Aging (Albany NY) 14 (2), 530, 2022 | 5 | 2022 |