Peter Bruno
Peter Bruno
Assistant Professor at UC-San Francisco
Verified email at - Homepage
Cited by
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A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress
PM Bruno, Y Liu, GY Park, J Murai, CE Koch, TJ Eisen, JR Pritchard, ...
Nature medicine 23 (4), 461-471, 2017
Defining principles of combination drug mechanisms of action
JR Pritchard, PM Bruno, LA Gilbert, KL Capron, DA Lauffenburger, ...
Proceedings of the National Academy of Sciences, 2012
A Pt (IV) pro-drug preferentially targets indoleamine-2, 3-dioxygenase, providing enhanced ovarian cancer immuno-chemotherapy
SG Awuah, YR Zheng, PM Bruno, MT Hemann, SJ Lippard
Journal of the American Chemical Society 137 (47), 14854-14857, 2015
Breast Cancer Stem Cell Potent Copper (II)–Non‐Steroidal Anti‐Inflammatory Drug Complexes
JN Boodram, IJ Mcgregor, PM Bruno, PB Cressey, MT Hemann, ...
Angewandte Chemie 128 (8), 2895-2900, 2016
The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning
PM Bruno, M Lu, KA Dennis, H Inam, CJ Moore, J Sheehe, SJ Elledge, ...
Proceedings of the National Academy of Sciences 117 (8), 4053-4060, 2020
Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation
CJ Braun, PM Bruno, MA Horlbeck, LA Gilbert, JS Weissman, MT Hemann
Proceedings of the National Academy of Sciences 113 (27), E3892-E3900, 2016
Bidentate ligands on osmium (VI) nitrido complexes control intracellular targeting and cell death pathways
K Suntharalingam, TC Johnstone, PM Bruno, W Lin, MT Hemann, ...
Journal of the American Chemical Society 135 (38), 14060-14063, 2013
A breast cancer stem cell-selective, mammospheres-potent osmium (VI) nitrido complex
K Suntharalingam, W Lin, TC Johnstone, PM Bruno, YR Zheng, ...
Journal of the American Chemical Society 136 (41), 14413-14416, 2014
Necroptosis-inducing rhenium (V) oxo complexes
K Suntharalingam, SG Awuah, PM Bruno, TC Johnstone, F Wang, W Lin, ...
Journal of the American Chemical Society 137 (8), 2967-2974, 2015
Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer
R Qi, Y Wang, PM Bruno, H Xiao, Y Yu, T Li, S Lauffer, W Wei, Q Chen, ...
Nature communications 8 (1), 2166, 2017
Using an RNAi signature assay to guide the design of three-drug-conjugated nanoparticles with validated mechanisms, in vivo efficacy, and low toxicity
JC Barnes, PM Bruno, HVT Nguyen, L Liao, J Liu, MT Hemann, ...
Journal of the American Chemical Society 138 (38), 12494-12501, 2016
Aneuploid cell survival relies upon sphingolipid homeostasis
YC Tang, H Yuwen, K Wang, PM Bruno, K Bullock, A Deik, S Santaguida, ...
Cancer research 77 (19), 5272-5286, 2017
The breast cancer stem cell potency of copper (II) complexes bearing nonsteroidal anti-inflammatory drugs and their encapsulation using polymeric nanoparticles
A Eskandari, JN Boodram, PB Cressey, C Lu, PM Bruno, MT Hemann, ...
Dalton Transactions 45 (44), 17867-17873, 2016
Induction of Necroptosis in Cancer Stem Cells using a Nickel (II)‐Dithiocarbamate Phenanthroline Complex
M Flamme, PB Cressey, C Lu, PM Bruno, A Eskandari, MT Hemann, ...
Chemistry–A European Journal 23 (40), 9674-9682, 2017
Predicting cancer drug mechanisms of action using molecular network signatures
JR Pritchard, PM Bruno, MT Hemann, DA Lauffenburger
Molecular bioSystems 9 (7), 1604-1619, 2013
The Potent Inhibitory Effect of a Naproxen‐Appended Cobalt (III)‐Cyclam Complex on Cancer Stem Cells
PB Cressey, A Eskandari, PM Bruno, C Lu, MT Hemann, ...
ChemBioChem 17 (18), 1713-1718, 2016
Mechanistic studies of the anticancer activity of an octahedral hexanuclear Pt (II) cage
YR Zheng, K Suntharalingam, PM Bruno, W Lin, W Wang, MT Hemann, ...
Inorganica chimica acta 452, 125-129, 2016
High-throughput, targeted MHC class I immunopeptidomics using a functional genetics screening platform
PM Bruno, RT Timms, NS Abdelfattah, Y Leng, FJN Lelis, DR Wesemann, ...
Nature Biotechnology, 1-13, 2023
The genomics revolution comes to the immunopeptidome
PM Bruno
Genes & Immunity, 1-3, 2023
Compositions and methods for epitope scanning
PM Bruno, SJ Elledge
US Patent App. 17/780,407, 2023
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