| A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress PM Bruno, Y Liu, GY Park, J Murai, CE Koch, TJ Eisen, JR Pritchard, ... Nature medicine 23 (4), 461-471, 2017 | 453 | 2017 |
| Defining principles of combination drug mechanisms of action JR Pritchard, PM Bruno, LA Gilbert, KL Capron, DA Lauffenburger, ... Proceedings of the National Academy of Sciences, 2012 | 178 | 2012 |
| A Pt (IV) pro-drug preferentially targets indoleamine-2, 3-dioxygenase, providing enhanced ovarian cancer immuno-chemotherapy SG Awuah, YR Zheng, PM Bruno, MT Hemann, SJ Lippard Journal of the American Chemical Society 137 (47), 14854-14857, 2015 | 156 | 2015 |
| Breast Cancer Stem Cell Potent Copper (II)–Non‐Steroidal Anti‐Inflammatory Drug Complexes JN Boodram, IJ Mcgregor, PM Bruno, PB Cressey, MT Hemann, ... Angewandte Chemie 128 (8), 2895-2900, 2016 | 138 | 2016 |
| The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning PM Bruno, M Lu, KA Dennis, H Inam, CJ Moore, J Sheehe, SJ Elledge, ... Proceedings of the National Academy of Sciences 117 (8), 4053-4060, 2020 | 127 | 2020 |
| Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation CJ Braun, PM Bruno, MA Horlbeck, LA Gilbert, JS Weissman, MT Hemann Proceedings of the National Academy of Sciences 113 (27), E3892-E3900, 2016 | 112 | 2016 |
| Bidentate ligands on osmium (VI) nitrido complexes control intracellular targeting and cell death pathways K Suntharalingam, TC Johnstone, PM Bruno, W Lin, MT Hemann, ... Journal of the American Chemical Society 135 (38), 14060-14063, 2013 | 104 | 2013 |
| A breast cancer stem cell-selective, mammospheres-potent osmium (VI) nitrido complex K Suntharalingam, W Lin, TC Johnstone, PM Bruno, YR Zheng, ... Journal of the American Chemical Society 136 (41), 14413-14416, 2014 | 94 | 2014 |
| Necroptosis-inducing rhenium (V) oxo complexes K Suntharalingam, SG Awuah, PM Bruno, TC Johnstone, F Wang, W Lin, ... Journal of the American Chemical Society 137 (8), 2967-2974, 2015 | 91 | 2015 |
| Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer R Qi, Y Wang, PM Bruno, H Xiao, Y Yu, T Li, S Lauffer, W Wei, Q Chen, ... Nature communications 8 (1), 2166, 2017 | 76 | 2017 |
| Using an RNAi signature assay to guide the design of three-drug-conjugated nanoparticles with validated mechanisms, in vivo efficacy, and low toxicity JC Barnes, PM Bruno, HVT Nguyen, L Liao, J Liu, MT Hemann, ... Journal of the American Chemical Society 138 (38), 12494-12501, 2016 | 56 | 2016 |
| Aneuploid cell survival relies upon sphingolipid homeostasis YC Tang, H Yuwen, K Wang, PM Bruno, K Bullock, A Deik, S Santaguida, ... Cancer research 77 (19), 5272-5286, 2017 | 51 | 2017 |
| The breast cancer stem cell potency of copper (II) complexes bearing nonsteroidal anti-inflammatory drugs and their encapsulation using polymeric nanoparticles A Eskandari, JN Boodram, PB Cressey, C Lu, PM Bruno, MT Hemann, ... Dalton Transactions 45 (44), 17867-17873, 2016 | 44 | 2016 |
| Induction of Necroptosis in Cancer Stem Cells using a Nickel (II)‐Dithiocarbamate Phenanthroline Complex M Flamme, PB Cressey, C Lu, PM Bruno, A Eskandari, MT Hemann, ... Chemistry–A European Journal 23 (40), 9674-9682, 2017 | 43 | 2017 |
| Predicting cancer drug mechanisms of action using molecular network signatures JR Pritchard, PM Bruno, MT Hemann, DA Lauffenburger Molecular bioSystems 9 (7), 1604-1619, 2013 | 34 | 2013 |
| The Potent Inhibitory Effect of a Naproxen‐Appended Cobalt (III)‐Cyclam Complex on Cancer Stem Cells PB Cressey, A Eskandari, PM Bruno, C Lu, MT Hemann, ... ChemBioChem 17 (18), 1713-1718, 2016 | 33 | 2016 |
| Mechanistic studies of the anticancer activity of an octahedral hexanuclear Pt (II) cage YR Zheng, K Suntharalingam, PM Bruno, W Lin, W Wang, MT Hemann, ... Inorganica chimica acta 452, 125-129, 2016 | 26 | 2016 |
| High-throughput, targeted MHC class I immunopeptidomics using a functional genetics screening platform PM Bruno, RT Timms, NS Abdelfattah, Y Leng, FJN Lelis, DR Wesemann, ... Nature biotechnology 41 (7), 980-992, 2023 | 11 | 2023 |
| The genomics revolution comes to the immunopeptidome PM Bruno Genes & Immunity, 1-3, 2023 | | 2023 |
| Compositions and methods for epitope scanning PM Bruno, SJ Elledge US Patent App. 17/780,407, 2023 | | 2023 |
