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Timothy E Van Meter
Timothy E Van Meter
Chief Scientific Officer, BRAINBox Solutions, Inc.; Affiliate Faculty, Pediatrics, VCU School of Medicine
Bestätigte E-Mail-Adresse bei brainboxinc.com
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Zitiert von
Zitiert von
Jahr
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ...
Cancer cell 22 (4), 425-437, 2012
19462012
Intertumoral heterogeneity within medulloblastoma subgroups
FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ...
Cancer cell 31 (6), 737-754. e6, 2017
10432017
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ...
Nature 488 (7409), 49-56, 2012
9612012
New brain tumor entities emerge from molecular classification of CNS-PNETs
D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ...
Cell 164 (5), 1060-1072, 2016
8252016
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
PA Northcott, Y Nakahara, X Wu, L Feuk, DW Ellison, S Croul, S Mack, ...
Nature genetics 41 (4), 465-472, 2009
4952009
Clonal selection drives genetic divergence of metastatic medulloblastoma
X Wu, PA Northcott, A Dubuc, AJ Dupuy, DJH Shih, H Witt, S Croul, ...
Nature 482 (7386), 529-533, 2012
4822012
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion
SE Golding, E Rosenberg, N Valerie, I Hussaini, M Frigerio, XF Cockcroft, ...
Molecular cancer therapeutics 8 (10), 2894-2902, 2009
3882009
The miR-17/92 polycistron is up-regulated in Sonic Hedgehog–driven medulloblastomas and induced by N-myc in Sonic Hedgehog–treated cerebellar neural precursors
PA Northcott, A Fernandez-L, JP Hagan, DW Ellison, W Grajkowska, ...
Cancer research 69 (8), 3249-3255, 2009
3372009
Integrated (epi)-genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors
J Torchia, B Golbourn, S Feng, KC Ho, P Sin-Chan, A Vasiljevic, ...
Cancer cell 30 (6), 891-908, 2016
2242016
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ...
Acta neuropathologica 126, 917-929, 2013
1992013
Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis
J Torchia, D Picard, L Lafay-Cousin, CE Hawkins, SK Kim, L Letourneau, ...
The lancet oncology 16 (5), 569-582, 2015
1812015
Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis
D Picard, S Miller, CE Hawkins, E Bouffet, HA Rogers, TSY Chan, SK Kim, ...
The lancet oncology 13 (8), 838-848, 2012
1772012
CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity
T Spence, P Sin-Chan, D Picard, M Barszczyk, K Hoss, M Lu, SK Kim, ...
Acta neuropathologica 128, 291-303, 2014
1652014
Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways
F Yang, V Jove, H Xin, M Hedvat, TE Van Meter, H Yu
Molecular Cancer Research 8 (1), 35-45, 2010
1212010
Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas
F Yang, TE Van Meter, R Buettner, M Hedvat, W Liang, CM Kowolik, ...
Molecular cancer therapeutics 7 (11), 3519-3526, 2008
1042008
Medulloblastoma subgroups remain stable across primary and metastatic compartments
X Wang, AM Dubuc, V Ramaswamy, S Mack, DMA Gendoo, M Remke, ...
Acta neuropathologica 129, 449-457, 2015
1002015
Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma
Y Nakahara, PA Northcott, M Li, PN Kongkham, C Smith, H Yan, S Croul, ...
Neoplasia 12 (1), 20-27, 2010
972010
Microarray analysis of MRI-defined tissue samples in glioblastoma reveals differences in regional expression of therapeutic targets
T Van Meter, C Dumur, N Hafez, C Garrett, H Fillmore, WC Broaddus
Diagnostic molecular pathology 15 (4), 195-205, 2006
902006
A C19MC-LIN28A-MYCN oncogenic circuit driven by hijacked super-enhancers is a distinct therapeutic vulnerability in ETMRs: a lethal brain tumor
P Sin-Chan, I Mumal, T Suwal, B Ho, X Fan, I Singh, Y Du, M Lu, N Patel, ...
Cancer cell 36 (1), 51-67. e7, 2019
822019
Epidermal growth factor induces matrix metalloproteinase-1 (MMP-1) expression and invasion in glioma cell lines via the MAPK pathway
M Anand, TE Van Meter, HL Fillmore
Journal of neuro-oncology 104, 679-687, 2011
712011
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