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Jerry F. Tien
Jerry F. Tien
Genome Sciences Centre, BC Cancer Agency
Verified email at bcgsc.ca
Title
Cited by
Cited by
Year
Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B
JF Tien, NT Umbreit, DR Gestaut, AD Franck, J Cooper, L Wordeman, ...
Journal of Cell Biology 189 (4), 713-723, 2010
2242010
The Ndc80 kinetochore complex directly modulates microtubule dynamics
NT Umbreit, DR Gestaut, JF Tien, BS Vollmar, T Gonen, CL Asbury, ...
Proceedings of the National Academy of Sciences 109 (40), 16113-16118, 2012
1292012
CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion
JF Tien, A Mazloomian, SWG Cheng, CS Hughes, CCT Chow, LT Canapi, ...
Nucleic acids research 45 (11), 6698-6716, 2017
1062017
Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II
SWG Cheng, MA Kuzyk, A Moradian, TA Ichu, VCD Chang, JF Tien, ...
Molecular and cellular biology 32 (22), 4691-4704, 2012
952012
Kinetochores’ gripping feat: conformational wave or biased diffusion?
CL Asbury, JF Tien, TN Davis
Trends in cell biology 21 (1), 38-46, 2011
662011
Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation
NT Umbreit, MP Miller, JF Tien, J Cattin OrtolŠ, L Gui, KK Lee, S Biggins, ...
Nature communications 5 (1), 1-11, 2014
562014
Kinetochore Biorientation in Saccharomyces cerevisiae Requires a Tightly Folded Conformation of the Ndc80 Complex
JF Tien, NT Umbreit, A Zelter, M Riffle, MR Hoopmann, RS Johnson, ...
Genetics 198 (4), 1483-1493, 2014
262014
Coupling Unbiased Mutagenesis to High-throughput DNA Sequencing Uncovers Functional Domains in the Ndc80 Kinetochore Protein of Saccharomyces cerevisiae
JF Tien, KK Fong, NT Umbreit, C Payen, A Zelter, CL Asbury, MJ Dunham, ...
Genetics 195 (1), 159-170, 2013
252013
VTT-006, an anti-mitotic compound, binds to the Ndc80 complex and suppresses cancer cell growth in vitro
LJ Laine, JHE Mški-Jouppila, E Kutvonen, P Tiikkainen, TKM Nyholm, ...
Oncoscience 8, 134, 2021
2021
Regulation of Ndc80-based microtubule attachments by the central kinetochore Mis12/MIND complex suggests a folding-based molecular mechanism
EA Scarborough, EM Kudalkar, N Umbreit, J Tien, CL Asbury, E Muller, ...
MOLECULAR BIOLOGY OF THE CELL 26, 2015
2015
Linker Scanning Mutagenesis of Yeast Microtubule Nucleating Components Spc97 and Spc98.
K Fong, J Tien, C Payen, A Zelter, B Graczyk, M Dunham, T Davis
MOLECULAR BIOLOGY OF THE CELL 25, 2014
2014
VTT-006, a novel anti-mitotic compound, binds to the Ndc80 complex and suppresses cancer cell growth in vitro
L Laine, J Maki-Jouppila, E Kutvonen, P Tiikkainen, T Nyholm, J Tien, ...
MOLECULAR BIOLOGY OF THE CELL 25, 2014
2014
Biophysical mechanisms of the kinetochore-microtubule interface and its regulation during mitosis
N Umbreit
2014
Linker scanning mutagenesis of yeast microtubule nucleating proteins Spc97 and Spc98 reveals essential functional and structural protein regions
K Fong, J Tien, C Payen, B Graczyk, A Zelter, M Dunham, T Davis
MOLECULAR BIOLOGY OF THE CELL 24, 2013
2013
Coupling unbiased mutagenesis to high-throughput sequencing uncovers functional domains in the yeast and human Ndc80 kinetochore proteins
J Tien, K Fong, N Umbreit, C Payen, A Zelter, C Asbury, M Dunham, ...
MOLECULAR BIOLOGY OF THE CELL 24, 2013
2013
Linker-scanning mutagenesis of the Ndc80 kinetochore protein
J Tien, K Fong, N Umbreit, C Payen, A Zelter, M Dunham, T Davis
MOLECULAR BIOLOGY OF THE CELL 23, 2012
2012
Linker scanning mutagenesis of yeast microtubule nucleating proteins Spc97 and Spc98
K Fong, J Tien, C Payen, B Graczyk, A Zelter, M Dunham, T Davis
MOLECULAR BIOLOGY OF THE CELL 23, 2012
2012
The human Ndc80 complex is a microtubule rescue factor regulated by Aurora B kinase.
D Gestaut, N Umbreit, J Tien, B Vollmar, T Gonen, C Asbury, T Davis
MOLECULAR BIOLOGY OF THE CELL 22, 2011
2011
The CrkRS/CDK12 kinase is activated by a novel isoform of Cyclin K and phosphorylates the C‐terminal domain of RNA Pol II
GB Morin, MA Kuzyk, JF Tien, E Schaeffer, SWG Cheng
The FASEB Journal 23, 492.3-492.3, 2009
2009
6 The role of chromatin structure in cell migration 12 Fungal evo–devo: organelles and multicellular complexity
M Capasso, TE DeCoursey, MJS Dyer, CT Pappas, KT Bliss, A Zieseniss, ...
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