Drug discovery in pharmaceutical industry: productivity challenges and trends I Khanna Drug discovery today 17 (19-20), 1088-1102, 2012 | 572 | 2012 |
Substituted pyrazolyl benzenesulfonamides JJ Talley, TD Penning, PW Collins, DJ Rogier Jr, JW Malecha, ... US Patent 5,466,823, 1995 | 313 | 1995 |
1, 2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents IK Khanna, RM Weier, Y Yu, XD Xu, FJ Koszyk, PW Collins, CM Koboldt, ... Journal of medicinal chemistry 40 (11), 1634-1647, 1997 | 265 | 1997 |
1, 2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2 IK Khanna, RM Weier, Y Yu, PW Collins, JM Miyashiro, CM Koboldt, ... Journal of medicinal chemistry 40 (11), 1619-1633, 1997 | 258 | 1997 |
1, 2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation IK Khanna, RM Weier, PW Collins, Y Yu, X Xu, RA Partis, FJ Koszyk US Patent 5,616,601, 1997 | 256 | 1997 |
Prodrugs of benzenesulfonamide-containing COX-2 inhibitors JJ Talley, JW Malecha, S Bertenshaw, MJ Graneto, J Carter, J Li, ... US Patent 5,932,598, 1999 | 217 | 1999 |
Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation JJ Talley, TD Penning, PW Collins, DJ Rogier Jr, JW Malecha, ... US Patent 5,760,068, 1998 | 205 | 1998 |
Buprenorphine–an attractive opioid with underutilized potential in treatment of chronic pain IK Khanna, S Pillarisetti Journal of pain research, 859-870, 2015 | 188 | 2015 |
Selective cyclooxygenase-2 inhibitors: heteroaryl modified 1, 2-diarylimidazoles are potent, orally active antiinflammatory agents IK Khanna, Y Yu, RM Huff, RM Weier, X Xu, FJ Koszyk, PW Collins, ... Journal of Medicinal Chemistry 43 (16), 3168-3185, 2000 | 146 | 2000 |
Pyrimidine compounds, process for their preparation and compositions containing them M Pal, S Kalleda, S Padakanti, NK Swamy, KR Yeleswarapu, ... US Patent 7,820,654, 2010 | 94 | 2010 |
Antimicrobial agents from higher plants: prenylated flavonoids and other phenols from Glycyrrhiza lepidota LA Mitscher, GSR Rao, I Khanna, T Veysoglu, S Drake Phytochemistry 22 (2), 573-576, 1983 | 85 | 1983 |
Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists S Sasmal, G Balaji, HRK Reddy, D Balasubrahmanyam, G Srinivas, ... Bioorganic & medicinal chemistry letters 22 (9), 3157-3162, 2012 | 77 | 2012 |
Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation JJ Talley, TD Penning, PW Collins, DJ Rogier Jr, JW Malecha, ... US Patent 5,563,165, 1996 | 77 | 1996 |
Facile, regioselective syntheses of N-alkylated 2, 3-diaminopyridines and imidazo [4, 5-b] pyridines IK Khanna, RM Weier, KT Lentz, L Swenton, DC Lankin The Journal of Organic Chemistry 60 (4), 960-965, 1995 | 73 | 1995 |
Convergent, parallel synthesis of a series of β-substituted 1, 2, 4-oxadiazole butanoic acids as potent and selective αvβ3 receptor antagonists ML Boys, LA Schretzman, NS Chandrakumar, MB Tollefson, SB Mohler, ... Bioorganic & medicinal chemistry letters 16 (4), 839-844, 2006 | 64 | 2006 |
Novel heterocyclic compounds as gata modulators CW Alexander, D De, IK Khanna, S Pillarisetti US Patent App. 12/553,623, 2010 | 60 | 2010 |
Pyridine compounds, process for their preparation and compositions containing them M Pal, CW Alexander, I Khanna, J Iqbal, R Pillarisetti, S Maitra, ... US Patent 7,622,486, 2009 | 59 | 2009 |
Substituted pyrazoles as p38 kinase inhibitors A Anantanarayan, M Clare, PW Collins, JZ Crich, R Devraj, DL Flynn, ... US Patent 6,423,713, 2002 | 59 | 2002 |
Methods for the treatment of diabetes-associated dyslipdemia U Saxena, S Pillarisetti, I Khanna US Patent 8,008,328, 2011 | 55 | 2011 |
Substituted pyrazoles as p38 kinase inhibitors A Anantanarayan, M Clare, PW Collins, JZ Crich, R Devraj, DL Flynn, ... US Patent 6,514,977, 2003 | 50 | 2003 |