AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner AP Seabright, NHF Fine, JP Barlow, SO Lord, I Musa, A Gray, JA Bryant, ... The FASEB Journal 34 (5), 6284, 2020 | 122 | 2020 |
Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells J Barlow, C Affourtit Biochemical Journal 456 (3), 417-426, 2013 | 67 | 2013 |
The benefits of physical exercise for the health of the pancreatic β‐cell: A review of the evidence M Curran, MT Drayson, RC Andrews, C Zoppi, JP Barlow, TPJ Solomon, ... Experimental Physiology 105 (4), 579-589, 2020 | 55 | 2020 |
Palmitate-induced impairment of glucose-stimulated insulin secretion precedes mitochondrial dysfunction in mouse pancreatic islets J Barlow, VH Jensen, M Jastroch, C Affourtit Biochemical Journal 473 (4), 487-496, 2016 | 54 | 2016 |
Do skeletal muscle-secreted factors influence the function of pancreatic β-cells? JP Barlow, TP Solomon American Journal of Physiology-Endocrinology and Metabolism 314 (4), E297-E307, 2018 | 52 | 2018 |
Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity–Novel … J Barlow, TPJ Solomon, C Affourtit PLoS One 13 (6), e0199505, 2018 | 38 | 2018 |
Control of pancreatic β-cell bioenergetics C Affourtit, B Alberts, J Barlow, JE Carré, AG Wynne Biochemical Society Transactions 46 (3), 555-564, 2018 | 27 | 2018 |
Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells J Barlow, VH Jensen, C Affourtit Redox biology 4, 14-22, 2015 | 24 | 2015 |
Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism JP Barlow, K Karstoft, A Vigelsø, M Gram, JW Helge, F Dela, K Pappan, ... Metabolism open 7, 100053, 2020 | 23 | 2020 |
Engineering amino acid uptake or catabolism promotes CAR T-cell adaption to the tumor environment S Panetti, N McJannett, L Fultang, S Booth, L Gneo, U Scarpa, C Smith, ... Blood Advances 7 (9), 1754-1761, 2023 | 19 | 2023 |
Conditioned media from contracting skeletal muscle potentiates insulin secretion and enhances mitochondrial energy metabolism of pancreatic beta-cells J Barlow, TPJ Solomon Metabolism 91, 1-9, 2019 | 18 | 2019 |
Probing the effect of physiological concentrations of IL-6 on insulin secretion by INS-1 832/3 insulinoma cells under diabetic-like conditions J Barlow, S Carter, TPJ Solomon International Journal of Molecular Sciences 19 (7), 1924, 2018 | 9 | 2018 |
(–)‐Epicatechin Alters Reactive Oxygen and Nitrogen Species Production Independent of Mitochondrial Respiration in Human Vascular Endothelial Cells DG Sadler, J Barlow, R Draijer, H Jones, DHJ Thijssen, CE Stewart Oxidative medicine and cellular longevity 2022 (1), 4413191, 2022 | 8 | 2022 |
Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice D Nasteska, F Cuozzo, K Viloria, EM Johnson, A Thakker, RB Bakar, ... JCI insight 6 (16), 2021 | 7 | 2021 |
Real-time assessment of neutrophil metabolism and oxidative burst using extracellular flux analysis FS Grudzinska, A Jasper, E Sapey, DR Thickett, C Mauro, A Scott, ... Frontiers in immunology 14, 1083072, 2023 | 6 | 2023 |
Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment V Stavrou, L Fultang, S Booth, D De Simone, A Bartnik, U Scarpa, L Gneo, ... Cancer Immunology, Immunotherapy 72 (3), 543-560, 2023 | 5 | 2023 |
On the role of mitochondria in pancreatic beta cells J Barlow, V Hirschberg, C Affourtit Research on Diabetes 1, 2013 | 5 | 2013 |
Measuring mitochondrial uncoupling protein-2 level and activity in insulinoma cells J Barlow, V Hirschberg, MD Brand, C Affourtit Methods in Enzymology 528, 257-267, 2013 | 4 | 2013 |
Exploring mitochondrial energy metabolism of single 3D microtissue spheroids using extracellular flux analysis NJ Coltman, G Rochford, NJ Hodges, H Ali-Boucetta, JP Barlow JoVE (Journal of Visualized Experiments), e63346, 2022 | 3 | 2022 |
PITX2 deficiency leads to atrial mitochondrial dysfunction JS Reyat, LC Sommerfeld, M O’Reilly, V Roth Cardoso, E Thiemann, ... Cardiovascular Research, cvae169, 2024 | 1 | 2024 |