Jonathan Barlow
Jonathan Barlow
Research Fellow, University of Birmingham
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AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner
AP Seabright, NHF Fine, JP Barlow, SO Lord, I Musa, A Gray, JA Bryant, ...
The FASEB Journal 34 (5), 6284, 2020
Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells
J Barlow, C Affourtit
Biochemical Journal 456 (3), 417-426, 2013
Do skeletal muscle-secreted factors influence the function of pancreatic β-cells?
JP Barlow, TP Solomon
American Journal of Physiology-Endocrinology and Metabolism 314 (4), E297-E307, 2018
Palmitate-induced impairment of glucose-stimulated insulin secretion precedes mitochondrial dysfunction in mouse pancreatic islets
J Barlow, VH Jensen, M Jastroch, C Affourtit
Biochemical Journal 473 (4), 487-496, 2016
The benefits of physical exercise for the health of the pancreatic β‐cell: a review of the evidence
M Curran, MT Drayson, RC Andrews, C Zoppi, JP Barlow, TPJ Solomon, ...
Experimental Physiology 105 (4), 579-589, 2020
Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity–Novel …
J Barlow, TPJ Solomon, C Affourtit
PLoS One 13 (6), e0199505, 2018
Control of pancreatic β-cell bioenergetics
C Affourtit, B Alberts, J Barlow, JE Carré, AG Wynne
Biochemical Society Transactions 46 (3), 555-564, 2018
Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells
J Barlow, VH Jensen, C Affourtit
Redox biology 4, 14-22, 2015
Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism
JP Barlow, K Karstoft, A Vigelsø, M Gram, JW Helge, F Dela, K Pappan, ...
Metabolism open 7, 100053, 2020
Conditioned media from contracting skeletal muscle potentiates insulin secretion and enhances mitochondrial energy metabolism of pancreatic beta-cells
J Barlow, TPJ Solomon
Metabolism 91, 1-9, 2019
Engineering amino acid uptake or catabolism promotes CAR T-cell adaption to the tumor environment
S Panetti, N McJannett, L Fultang, S Booth, L Gneo, U Scarpa, C Smith, ...
Blood Advances 7 (9), 1754-1761, 2023
Probing the effect of physiological concentrations of IL-6 on insulin secretion by INS-1 832/3 insulinoma cells under diabetic-like conditions
J Barlow, S Carter, TPJ Solomon
International Journal of Molecular Sciences 19 (7), 1924, 2018
(–)-Epicatechin alters reactive oxygen and nitrogen species production independent of mitochondrial respiration in human vascular endothelial cells
DG Sadler, J Barlow, R Draijer, H Jones, DHJ Thijssen, CE Stewart
Oxidative medicine and cellular longevity 2022, 2022
Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice
D Nasteska, F Cuozzo, K Viloria, EM Johnson, A Thakker, RB Bakar, ...
JCI insight 6 (16), 2021
On the role of mitochondria in pancreatic beta cells
J Barlow, V Hirschberg, C Affourtit
Research on Diabetes 1, 2013
Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment
V Stavrou, L Fultang, S Booth, D De Simone, A Bartnik, U Scarpa, L Gneo, ...
Cancer Immunology, Immunotherapy 72 (3), 543-560, 2023
Measuring mitochondrial uncoupling protein-2 level and activity in insulinoma cells
J Barlow, V Hirschberg, MD Brand, C Affourtit
Methods in Enzymology 528, 257-267, 2013
Real-time assessment of neutrophil metabolism and oxidative burst using extracellular flux analysis
FS Grudzinska, A Jasper, E Sapey, DR Thickett, C Mauro, A Scott, ...
Frontiers in immunology 14, 1083072, 2023
Exploring Mitochondrial Energy Metabolism of Single 3D Microtissue Spheroids using Extracellular Flux Analysis
NJ Coltman, G Rochford, NJ Hodges, H Ali-Boucetta, JP Barlow
JoVE (Journal of Visualized Experiments), e63346, 2022
Skeletal-muscle To Pancreatic Beta-cell Crosstalk: The Influence Of Interleukin-6: 1283 June 1 9: 00 AM-9: 15 AM
JP Barlow, TP Solomon
Medicine & Science in Sports & Exercise 49 (5S), 347, 2017
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